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The map label for this gene is glnP [H]

Identifier: 116248748

GI number: 116248748

Start: 74131

End: 74820

Strand: Direct

Name: glnP [H]

Synonym: pRL120072

Alternate gene names: 116248748

Gene position: 74131-74820 (Clockwise)

Preceding gene: 116248747

Following gene: 116248749

Centisome position: 8.52

GC content: 59.71

Gene sequence:

>690_bases
ATGCTCTGGTCTGAAAGGGCGGCCCGTATGGGTTACACGTTGAATTTCGCTGCCGTCTGGCGCAACTTCGATTTTCTTTT
GAGCGGGCTCGCGCTCAGTCTCGGCCTTGCGGTGATCTCGATCCTGATCGGGGCCGCGATCGGTCTTGTGGTGGCCTTCG
CGCTGACGTCCAAAAACCGCTTTGCGGTCGTGCCGGCACGGATCTATGTCACTGTCATCCGCAACCTGCCGATTCTCGTC
CTGGTGCTTTTTGTCTTTTTCGCGCTGCCGCAAATGGGTTTGCGCCTCGACAAGATAAAAAGCTTCGTCCTGGTTCTGTC
GCTTTATTCCGGCGCCTATCTGGCCGAGGTGTTCCGCGCCGGTCTGCTGTCTATTCCAAGAGGGTTGACGGAAGCGGGGC
TTGCCATCGGCCTGACGGGGATGCAGATCCGCAGCTCCATCATCGCTCCGCTGATGCTGCGCAACGTGCTGCCATCACTG
TCCTCGACGATCATCTCGCTCTTCAAGGACACCTCGCTCGCCGCCGCCATCGCCGTGCCCGAACTGACCTTTGCTGCCCG
CAAGATCAATGTCGAGAGCTTCCGCGTCATAGAGACCTGGATGGTCACATCAGCGCTCTATGTCGCGACCTGTTTCCTCA
TCGCCGCCGTGATGCGCTTCGTCGAGCGCCGCCTGGCCCTGCCGAGATAG

Upstream 100 bases:

>100_bases
GTTCAAGTAACAGCCATGCGGAGCGGGACATGTTTCCCGCTCCGCATTTAAAGGGTGAGAGCATGATGCCGTCCGAAAAC
CGTTCATATTTTTCGGCCTC

Downstream 100 bases:

>100_bases
ACCCGATGTCCCACACCTTTCTCGAACAACTCTGGATCGCCCGCTACGTCATCATGAACGGCATCGGCGTGACCGTGTCG
ATCTCCCTGCTGGCCATCCT

Product: putative permease component of ABC transporter

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MLWSERAARMGYTLNFAAVWRNFDFLLSGLALSLGLAVISILIGAAIGLVVAFALTSKNRFAVVPARIYVTVIRNLPILV
LVLFVFFALPQMGLRLDKIKSFVLVLSLYSGAYLAEVFRAGLLSIPRGLTEAGLAIGLTGMQIRSSIIAPLMLRNVLPSL
SSTIISLFKDTSLAAAIAVPELTFAARKINVESFRVIETWMVTSALYVATCFLIAAVMRFVERRLALPR

Sequences:

>Translated_229_residues
MLWSERAARMGYTLNFAAVWRNFDFLLSGLALSLGLAVISILIGAAIGLVVAFALTSKNRFAVVPARIYVTVIRNLPILV
LVLFVFFALPQMGLRLDKIKSFVLVLSLYSGAYLAEVFRAGLLSIPRGLTEAGLAIGLTGMQIRSSIIAPLMLRNVLPSL
SSTIISLFKDTSLAAAIAVPELTFAARKINVESFRVIETWMVTSALYVATCFLIAAVMRFVERRLALPR
>Mature_229_residues
MLWSERAARMGYTLNFAAVWRNFDFLLSGLALSLGLAVISILIGAAIGLVVAFALTSKNRFAVVPARIYVTVIRNLPILV
LVLFVFFALPQMGLRLDKIKSFVLVLSLYSGAYLAEVFRAGLLSIPRGLTEAGLAIGLTGMQIRSSIIAPLMLRNVLPSL
SSTIISLFKDTSLAAAIAVPELTFAARKINVESFRVIETWMVTSALYVATCFLIAAVMRFVERRLALPR

Specific function: Part of the binding-protein-dependent transport system for glutamine; probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787030, Length=215, Percent_Identity=36.2790697674419, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1788226, Length=204, Percent_Identity=34.3137254901961, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788645, Length=218, Percent_Identity=27.9816513761468, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788646, Length=213, Percent_Identity=27.6995305164319, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787087, Length=223, Percent_Identity=27.3542600896861, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1786874, Length=236, Percent_Identity=28.3898305084746, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1786873, Length=225, Percent_Identity=28.4444444444444, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI48994930, Length=134, Percent_Identity=32.8358208955224, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI87082239, Length=208, Percent_Identity=27.4038461538462, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1787086, Length=218, Percent_Identity=27.0642201834862, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25013; Mature: 25013

Theoretical pI: Translated: 11.40; Mature: 11.40

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWSERAARMGYTLNFAAVWRNFDFLLSGLALSLGLAVISILIGAAIGLVVAFALTSKNR
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FAVVPARIYVTVIRNLPILVLVLFVFFALPQMGLRLDKIKSFVLVLSLYSGAYLAEVFRA
EEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHH
GLLSIPRGLTEAGLAIGLTGMQIRSSIIAPLMLRNVLPSLSSTIISLFKDTSLAAAIAVP
HHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELTFAARKINVESFRVIETWMVTSALYVATCFLIAAVMRFVERRLALPR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLWSERAARMGYTLNFAAVWRNFDFLLSGLALSLGLAVISILIGAAIGLVVAFALTSKNR
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FAVVPARIYVTVIRNLPILVLVLFVFFALPQMGLRLDKIKSFVLVLSLYSGAYLAEVFRA
EEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHH
GLLSIPRGLTEAGLAIGLTGMQIRSSIIAPLMLRNVLPSLSSTIISLFKDTSLAAAIAVP
HHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELTFAARKINVESFRVIETWMVTSALYVATCFLIAAVMRFVERRLALPR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]