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The map label for this gene is iolG [H]

Identifier: 116248700

GI number: 116248700

Start: 22552

End: 23700

Strand: Reverse

Name: iolG [H]

Synonym: pRL120024

Alternate gene names: 116248700

Gene position: 23700-22552 (Counterclockwise)

Preceding gene: 116248702

Following gene: 116248699

Centisome position: 2.72

GC content: 63.79

Gene sequence:

>1149_bases
ATGGCACAGACCAATGGTATGAAACTCAGGATCGGCGTGGTGGGATGCGGCAACATTTCGCTCGCCTATATGCGCAACGC
GCCGCTGTTTTGCGGCGTCGAAATCACCGCCTGTGCAGATCTCAACGCCGATGCTGCCAAGCGTCGCGCGGCGGAGTTCA
ATTTGCGCGCAGCTGACGTCGATAGCCTCATTGACGACAGGAACATCGACCTCATCCTGAACCTGACGATCCCGGCTGCG
CATTTTGACGTTTCGATGCGGGCTCTGTCGACAGGCAAGCATGTCTTCACGGAGAAGCCGCTCGGCGTCACGGCCGCAGA
AGGACGCAGCCTGGTGGATGCCGCCGCGGCGAAGGGCCTCATGCTCGGCTCGGCGCCAGACACGTTCCTCGGCGCGGCTG
GACGCCATGCCCGGCGGCAGATGGAAGCCGGCGCCATCGGCAAGCCGGTGACCGGGACTGCCTTCATGATGGGGCGCGGC
ATGGAGCACTGGCATCCGGATCCCAGCTTTTATTACCAGGCCGGTGCAGGCCCGCTGATGGATATGGGGCCTTATTATCT
CACGATGATGGTCAATCTGATGGGGCCGATCCGCCGTGTGCAGGCCGTCGCCACAAGCGGGCAGGAAGAGCGGCTCATCA
CGGCGGAGGGACCGAAGCAGGGCACCACGTTCAAGGTCGGCACGCCGACCAGCGTGCAGTCGCTGCTGGAATTCGATTGC
GGTGCGACGGTCACCTTCGGCACCTCCTGGGACGTATTCCGCCATTCCAACCACCCCATCGAACTCCACGGAACCGAAGG
CTCGCTGCGCCTGCCCGACCCCGACAATTTCGGCGGCTCCGTCGCGCTCTCCGGCCGCGGCGCGCCCTGGCAGGAAACGG
ACACGTCAGGCGAACTCTTCGGTGCCGTCAATTGGCCGATCGCAGCGCCTGATCGTGCCAACTATCGCATGCTTGGTCTT
GCCGATCTCGCACGCGCAATCATCGAAGGCCGCAAGCCCCGCGCTTCGGGCGATCTGGCGCTGCACGTGCTCGAAGTCAT
GGAAGCGATCCTGCGTGCCGGCGAAACCGGTCTCGCGCAGACCATTTCGGGTACCGTCGCGCAGCCGAGGGAATTGCGGG
AAGACGAAGCGAGGAGTTTGCTGGCATGA

Upstream 100 bases:

>100_bases
GTCAAATGTTACCGTACGTCAACATATTTTATTCCTTGCGATTAAAATGTAACGCACCCCTCAACCCTTCGCACCCGCTA
CGGCAAAATCAGGTTCTTAG

Downstream 100 bases:

>100_bases
CACAACTGGATGAATCCGCCAAACGCGCGCTTGCATGGCCTGGCGATCCGCAAACGCCGGTCGAAAGCTGCACTCCGGCA
CTGGCGCGGCAGCAATATCT

Product: GFO/IDH/MocA family oxidoreductase

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase; MI 2-dehydrogenase/DCI 3-dehydrogenase [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MAQTNGMKLRIGVVGCGNISLAYMRNAPLFCGVEITACADLNADAAKRRAAEFNLRAADVDSLIDDRNIDLILNLTIPAA
HFDVSMRALSTGKHVFTEKPLGVTAAEGRSLVDAAAAKGLMLGSAPDTFLGAAGRHARRQMEAGAIGKPVTGTAFMMGRG
MEHWHPDPSFYYQAGAGPLMDMGPYYLTMMVNLMGPIRRVQAVATSGQEERLITAEGPKQGTTFKVGTPTSVQSLLEFDC
GATVTFGTSWDVFRHSNHPIELHGTEGSLRLPDPDNFGGSVALSGRGAPWQETDTSGELFGAVNWPIAAPDRANYRMLGL
ADLARAIIEGRKPRASGDLALHVLEVMEAILRAGETGLAQTISGTVAQPRELREDEARSLLA

Sequences:

>Translated_382_residues
MAQTNGMKLRIGVVGCGNISLAYMRNAPLFCGVEITACADLNADAAKRRAAEFNLRAADVDSLIDDRNIDLILNLTIPAA
HFDVSMRALSTGKHVFTEKPLGVTAAEGRSLVDAAAAKGLMLGSAPDTFLGAAGRHARRQMEAGAIGKPVTGTAFMMGRG
MEHWHPDPSFYYQAGAGPLMDMGPYYLTMMVNLMGPIRRVQAVATSGQEERLITAEGPKQGTTFKVGTPTSVQSLLEFDC
GATVTFGTSWDVFRHSNHPIELHGTEGSLRLPDPDNFGGSVALSGRGAPWQETDTSGELFGAVNWPIAAPDRANYRMLGL
ADLARAIIEGRKPRASGDLALHVLEVMEAILRAGETGLAQTISGTVAQPRELREDEARSLLA
>Mature_381_residues
AQTNGMKLRIGVVGCGNISLAYMRNAPLFCGVEITACADLNADAAKRRAAEFNLRAADVDSLIDDRNIDLILNLTIPAAH
FDVSMRALSTGKHVFTEKPLGVTAAEGRSLVDAAAAKGLMLGSAPDTFLGAAGRHARRQMEAGAIGKPVTGTAFMMGRGM
EHWHPDPSFYYQAGAGPLMDMGPYYLTMMVNLMGPIRRVQAVATSGQEERLITAEGPKQGTTFKVGTPTSVQSLLEFDCG
ATVTFGTSWDVFRHSNHPIELHGTEGSLRLPDPDNFGGSVALSGRGAPWQETDTSGELFGAVNWPIAAPDRANYRMLGLA
DLARAIIEGRKPRASGDLALHVLEVMEAILRAGETGLAQTISGTVAQPRELREDEARSLLA

Specific function: Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 40719; Mature: 40588

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQTNGMKLRIGVVGCGNISLAYMRNAPLFCGVEITACADLNADAAKRRAAEFNLRAADV
CCCCCCCEEEEEEEEECCEEEEEEECCCEEECEEEEEEECCCCHHHHHHHHHCCCCHHHH
DSLIDDRNIDLILNLTIPAAHFDVSMRALSTGKHVFTEKPLGVTAAEGRSLVDAAAAKGL
HHHHCCCCCEEEEEEEECCHHHCEEHHHHHCCCEEEECCCCCEECCCCCHHHHHHHHCCE
MLGSAPDTFLGAAGRHARRQMEAGAIGKPVTGTAFMMGRGMEHWHPDPSFYYQAGAGPLM
EECCCCCHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHCCCCHHCCCCCCEEEECCCCCCH
DMGPYYLTMMVNLMGPIRRVQAVATSGQEERLITAEGPKQGTTFKVGTPTSVQSLLEFDC
HCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCHHHHHHHHHCC
GATVTFGTSWDVFRHSNHPIELHGTEGSLRLPDPDNFGGSVALSGRGAPWQETDTSGELF
CCEEEECCCCHHHCCCCCCEEEECCCCCEECCCCCCCCCEEEECCCCCCCCCCCCCCCEE
GAVNWPIAAPDRANYRMLGLADLARAIIEGRKPRASGDLALHVLEVMEAILRAGETGLAQ
EEECCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHH
TISGTVAQPRELREDEARSLLA
HHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AQTNGMKLRIGVVGCGNISLAYMRNAPLFCGVEITACADLNADAAKRRAAEFNLRAADV
CCCCCCEEEEEEEEECCEEEEEEECCCEEECEEEEEEECCCCHHHHHHHHHCCCCHHHH
DSLIDDRNIDLILNLTIPAAHFDVSMRALSTGKHVFTEKPLGVTAAEGRSLVDAAAAKGL
HHHHCCCCCEEEEEEEECCHHHCEEHHHHHCCCEEEECCCCCEECCCCCHHHHHHHHCCE
MLGSAPDTFLGAAGRHARRQMEAGAIGKPVTGTAFMMGRGMEHWHPDPSFYYQAGAGPLM
EECCCCCHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHCCCCHHCCCCCCEEEECCCCCCH
DMGPYYLTMMVNLMGPIRRVQAVATSGQEERLITAEGPKQGTTFKVGTPTSVQSLLEFDC
HCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCHHHHHHHHHCC
GATVTFGTSWDVFRHSNHPIELHGTEGSLRLPDPDNFGGSVALSGRGAPWQETDTSGELF
CCEEEECCCCHHHCCCCCCEEEECCCCCEECCCCCCCCCEEEECCCCCCCCCCCCCCCEE
GAVNWPIAAPDRANYRMLGLADLARAIIEGRKPRASGDLALHVLEVMEAILRAGETGLAQ
EEECCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHH
TISGTVAQPRELREDEARSLLA
HHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA