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The map label for this gene is agaR [H]

Identifier: 116248702

GI number: 116248702

Start: 24897

End: 25658

Strand: Reverse

Name: agaR [H]

Synonym: pRL120026

Alternate gene names: 116248702

Gene position: 25658-24897 (Counterclockwise)

Preceding gene: 116248717

Following gene: 116248700

Centisome position: 2.95

GC content: 61.94

Gene sequence:

>762_bases
ATGCTTGCAGAACAGAGGCGGCAGCAGATCATGCTGGAACTTCAACGGGTCGGCCAGGCACGCACCCGCCAGCTCGCGGA
ATTCTTCGAAGTCTCGGAAGTGACGATCCGCTCCGATCTCGAAATCATGGACGCCAAGAAGCAGCTGATCAAAACGCATG
GCGGGGCAATCGCCCTGCCGTCCGACTCGCCGGCAGCGGCCTTCGAGGAACGCATGCAGCGCAATTTCGATGCGAAGCGA
CGCATCGCCCAGATGGCTGCGCGACAGATCATCGATAACCAGTCGATCGTCTTCGACAGCGGTTCGACCCTGCTGCAGGT
GGCCATGCAGATGCCACCGGTCAACAACGTCGTGGTTGCGACAACGGCGATGAACATCGCCCAGCATCTGATGTACCGGC
CAGGGCTCGACGTGCACATGATCGGCGGCCGCGTATTTCCCAGTACCGTGAGCACGATCGTACAGGACTCCGACAAGGCG
GTCGGCGGCCTCGTCGCCCACCAGGCTTTTGTCGGCGCCCACGCGATCGATCAGGCCTTCGATGTCGTCGATGTCTCCGA
GGACGTGGCGCGGACCAAGCGTAACCTGGTTCGCATGGCCCGGCGTGTCGTCCTCGTGGCGGATTCGAGCAAATTTGACA
TCGGCGCCTCCTCCAAAGCCTTCTCGCTGTCGCGCGTCGACCTGATCATCACGGACAGCAACATGCCGCACAGCATTCGC
CACCGGCTGGACAAGCTGGGCGTGGAGGTTCGCTACGCGTGA

Upstream 100 bases:

>100_bases
ATCGAACGGCTATTTCTGCAGCAAGAGCCGTGGAATAAGACGGTGAACTTTCGTTTTTCAAAAGTCGCATTGTTGCATAT
AACGGCAGTCGGGATCACAT

Downstream 100 bases:

>100_bases
CCTGCAGTCAACCTGTCCATTTCAGAAGAGAGCCGAGAGAGGCTTTGGTGCGGGCCGAAGGCCCCAGCCGATGCCGGGGA
AAGCGAGATAGGCTAAAATC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MLAEQRRQQIMLELQRVGQARTRQLAEFFEVSEVTIRSDLEIMDAKKQLIKTHGGAIALPSDSPAAAFEERMQRNFDAKR
RIAQMAARQIIDNQSIVFDSGSTLLQVAMQMPPVNNVVVATTAMNIAQHLMYRPGLDVHMIGGRVFPSTVSTIVQDSDKA
VGGLVAHQAFVGAHAIDQAFDVVDVSEDVARTKRNLVRMARRVVLVADSSKFDIGASSKAFSLSRVDLIITDSNMPHSIR
HRLDKLGVEVRYA

Sequences:

>Translated_253_residues
MLAEQRRQQIMLELQRVGQARTRQLAEFFEVSEVTIRSDLEIMDAKKQLIKTHGGAIALPSDSPAAAFEERMQRNFDAKR
RIAQMAARQIIDNQSIVFDSGSTLLQVAMQMPPVNNVVVATTAMNIAQHLMYRPGLDVHMIGGRVFPSTVSTIVQDSDKA
VGGLVAHQAFVGAHAIDQAFDVVDVSEDVARTKRNLVRMARRVVLVADSSKFDIGASSKAFSLSRVDLIITDSNMPHSIR
HRLDKLGVEVRYA
>Mature_253_residues
MLAEQRRQQIMLELQRVGQARTRQLAEFFEVSEVTIRSDLEIMDAKKQLIKTHGGAIALPSDSPAAAFEERMQRNFDAKR
RIAQMAARQIIDNQSIVFDSGSTLLQVAMQMPPVNNVVVATTAMNIAQHLMYRPGLDVHMIGGRVFPSTVSTIVQDSDKA
VGGLVAHQAFVGAHAIDQAFDVVDVSEDVARTKRNLVRMARRVVLVADSSKFDIGASSKAFSLSRVDLIITDSNMPHSIR
HRLDKLGVEVRYA

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=248, Percent_Identity=30.6451612903226, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1789059, Length=254, Percent_Identity=30.7086614173228, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1789829, Length=239, Percent_Identity=29.7071129707113, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1790753, Length=254, Percent_Identity=27.1653543307087, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI87082344, Length=252, Percent_Identity=25.7936507936508, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI226510968, Length=248, Percent_Identity=26.2096774193548, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787540, Length=241, Percent_Identity=28.2157676348548, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787063, Length=231, Percent_Identity=25.1082251082251, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788069, Length=235, Percent_Identity=25.531914893617, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790635, Length=254, Percent_Identity=25.1968503937008, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28009; Mature: 28009

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS51000 HTH_DEOR_2 ; PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAEQRRQQIMLELQRVGQARTRQLAEFFEVSEVTIRSDLEIMDAKKQLIKTHGGAIALP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEEEC
SDSPAAAFEERMQRNFDAKRRIAQMAARQIIDNQSIVFDSGSTLLQVAMQMPPVNNVVVA
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCCEEEH
TTAMNIAQHLMYRPGLDVHMIGGRVFPSTVSTIVQDSDKAVGGLVAHQAFVGAHAIDQAF
HHHHHHHHHHHHCCCCCEEEECCEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
DVVDVSEDVARTKRNLVRMARRVVLVADSSKFDIGASSKAFSLSRVDLIITDSNMPHSIR
HHHCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHH
HRLDKLGVEVRYA
HHHHHHCCEEECC
>Mature Secondary Structure
MLAEQRRQQIMLELQRVGQARTRQLAEFFEVSEVTIRSDLEIMDAKKQLIKTHGGAIALP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEEEC
SDSPAAAFEERMQRNFDAKRRIAQMAARQIIDNQSIVFDSGSTLLQVAMQMPPVNNVVVA
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCCEEEH
TTAMNIAQHLMYRPGLDVHMIGGRVFPSTVSTIVQDSDKAVGGLVAHQAFVGAHAIDQAF
HHHHHHHHHHHHCCCCCEEEECCEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
DVVDVSEDVARTKRNLVRMARRVVLVADSSKFDIGASSKAFSLSRVDLIITDSNMPHSIR
HHHCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHH
HRLDKLGVEVRYA
HHHHHHCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]