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The map label for this gene is glpR [H]

Identifier: 116248692

GI number: 116248692

Start: 15287

End: 16072

Strand: Direct

Name: glpR [H]

Synonym: pRL120016

Alternate gene names: 116248692

Gene position: 15287-16072 (Clockwise)

Preceding gene: 116248691

Following gene: 116248693

Centisome position: 1.76

GC content: 59.41

Gene sequence:

>786_bases
ATGGGGCAGCGGATCATATCGAGCCGGCAACGTGAGATCCTCGCGCTGATCGAGACGGAAGGTGTTCAGTACATCGAGGA
ACTGGCACGTCGATACGATTTGACGACGCAGACGATCCGGCGCGATATCAATGCATTATGCGATCTCGGGCACGCGCGCC
GCTTTCACGGCGGCGTCGATCTGCCGGTCGAAGGCAGCAACATCTCGCTCAATGCTCGCGCCCAGCTCAATCGGCGCGCC
AAGCGGCTTATCGCCAAGCGTGTCGCTTCCGATATAGGTGCAGACGCGACAGTGTTTCTCGGGATCGGCAGTACGGTTCA
ATTCGTTGCCGAGGCGCTGCGTGATCATCAGGGGCTGACGGTGATCACCAACAACATCCACGTCGCCTTGAGCCTTTGCG
ACGCGCCGAGCGTCGAGGTTCATTTGACGGGCGGTCTTTTGCGTCACGATGACCGCGACGTGGTCGGCACGGATGTGATC
AGGTTCGTCGAAAAATTCTATGCGACTTACGCAATTGTCGGCGCAGGCGCTTTGAGCCCGCTGAACGGACTGATGGACTT
CAGCTACAGCGAAGCCCAGATCACCAATGCCCTCCTTGAGAATTCACAAACGCAGATCCTGGCCGCGGACGTCAGCAAGT
GGACGCGCAACGCGGCCGTGCGTGTTGCGCCATTCAGCAAACTCACCCGTTTCTACACCGATCGGCTGCCTGGCGACGCG
GCCGCCACCAATGCTCTCGCCGAGAGCGGCTTGGATGTGGTCACATGCAGCGAGGATATGACATGA

Upstream 100 bases:

>100_bases
GACTTGCAACGATCCCAGGCGGCTCGCATCGTTCTGGGATGTGGGTTTGACCGGTGTGATAACAGACGACCCCAGTGTCT
ACCTCACGTAAGGAGCGGCG

Downstream 100 bases:

>100_bases
GCTATGTAGACTTGGCGCCATCAGCTCGTGAATTACGGGATGTACGCTACCTGTTCACCGACATCGACGATACGCTGACC
ACCGAAGGCAAGTTACTGCC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MGQRIISSRQREILALIETEGVQYIEELARRYDLTTQTIRRDINALCDLGHARRFHGGVDLPVEGSNISLNARAQLNRRA
KRLIAKRVASDIGADATVFLGIGSTVQFVAEALRDHQGLTVITNNIHVALSLCDAPSVEVHLTGGLLRHDDRDVVGTDVI
RFVEKFYATYAIVGAGALSPLNGLMDFSYSEAQITNALLENSQTQILAADVSKWTRNAAVRVAPFSKLTRFYTDRLPGDA
AATNALAESGLDVVTCSEDMT

Sequences:

>Translated_261_residues
MGQRIISSRQREILALIETEGVQYIEELARRYDLTTQTIRRDINALCDLGHARRFHGGVDLPVEGSNISLNARAQLNRRA
KRLIAKRVASDIGADATVFLGIGSTVQFVAEALRDHQGLTVITNNIHVALSLCDAPSVEVHLTGGLLRHDDRDVVGTDVI
RFVEKFYATYAIVGAGALSPLNGLMDFSYSEAQITNALLENSQTQILAADVSKWTRNAAVRVAPFSKLTRFYTDRLPGDA
AATNALAESGLDVVTCSEDMT
>Mature_260_residues
GQRIISSRQREILALIETEGVQYIEELARRYDLTTQTIRRDINALCDLGHARRFHGGVDLPVEGSNISLNARAQLNRRAK
RLIAKRVASDIGADATVFLGIGSTVQFVAEALRDHQGLTVITNNIHVALSLCDAPSVEVHLTGGLLRHDDRDVVGTDVIR
FVEKFYATYAIVGAGALSPLNGLMDFSYSEAQITNALLENSQTQILAADVSKWTRNAAVRVAPFSKLTRFYTDRLPGDAA
ATNALAESGLDVVTCSEDMT

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082344, Length=253, Percent_Identity=34.3873517786561, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1789829, Length=231, Percent_Identity=33.7662337662338, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1789059, Length=254, Percent_Identity=29.1338582677165, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787540, Length=230, Percent_Identity=27.8260869565217, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789519, Length=256, Percent_Identity=25.390625, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1788069, Length=209, Percent_Identity=28.2296650717703, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI226510968, Length=248, Percent_Identity=26.2096774193548, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28455; Mature: 28323

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQRIISSRQREILALIETEGVQYIEELARRYDLTTQTIRRDINALCDLGHARRFHGGVD
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHCCCCC
LPVEGSNISLNARAQLNRRAKRLIAKRVASDIGADATVFLGIGSTVQFVAEALRDHQGLT
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCEE
VITNNIHVALSLCDAPSVEVHLTGGLLRHDDRDVVGTDVIRFVEKFYATYAIVGAGALSP
EEECCEEEEEEECCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
LNGLMDFSYSEAQITNALLENSQTQILAADVSKWTRNAAVRVAPFSKLTRFYTDRLPGDA
HHHHHCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHCCEEEECCHHHHHHHHHHCCCCHH
AATNALAESGLDVVTCSEDMT
HHHHHHHHCCCCEEECCCCCC
>Mature Secondary Structure 
GQRIISSRQREILALIETEGVQYIEELARRYDLTTQTIRRDINALCDLGHARRFHGGVD
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHCCCCC
LPVEGSNISLNARAQLNRRAKRLIAKRVASDIGADATVFLGIGSTVQFVAEALRDHQGLT
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCEE
VITNNIHVALSLCDAPSVEVHLTGGLLRHDDRDVVGTDVIRFVEKFYATYAIVGAGALSP
EEECCEEEEEEECCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
LNGLMDFSYSEAQITNALLENSQTQILAADVSKWTRNAAVRVAPFSKLTRFYTDRLPGDA
HHHHHCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHCCEEEECCHHHHHHHHHHCCCCHH
AATNALAESGLDVVTCSEDMT
HHHHHHHHCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]