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The map label for this gene is dapA [H]

Identifier: 116248680

GI number: 116248680

Start: 3773

End: 4657

Strand: Direct

Name: dapA [H]

Synonym: pRL120004

Alternate gene names: 116248680

Gene position: 3773-4657 (Clockwise)

Preceding gene: 116248679

Following gene: 116248681

Centisome position: 0.43

GC content: 59.44

Gene sequence:

>885_bases
TTGACACAAAAATTCGGGCTCTCGGTCGCTCTCGCCACACCGTTCGACAGCAATGGCGATATCGCGATCGAGGCGATGAT
CGAGCAGGCACGGCGAAGCCTCGCTGCGGGGTGCTCGAGTGTGACCCTGTTCGGGACGACGGGTGAAGGTTCTTCCATCG
GCACCCGGGAACGTGAGCGTGTTCTCGCTTCCTTGCTCGATAGTGGGATAGCAGCAAAGCAGATCATCGTCGGTGTGCTG
GTCGACGCGGCCGAGGATGCGGCGATGCAGGCCGGCCATGCGCTTTCCAAAGGAGCCCGCAATATCCTCCTTGCTCCCCC
TTCCTATTTCAAGAACGTGAGTGACGATGGCGTCTTCCAGTGGTTTTCGGCTGTTTTCACCATCCTGGGCGACAAGGCGC
GAGACATTATCGTCTACAACATTCCCTCGGTCACCATGGTTCCGCTGAGCGTATCGCTCATCGGCCGGCTACGGACCGCC
TTTCCCGATATCGTCACGGGCGTCAAGGATTCCTCCGGCGACTGGCCTTTCACGGAAGCGCTGTTGAAGGCGCATGGCGA
TCTCGTCATCCTGGTGGGCGACGAGCGTCACTTGGCGAAGGGCGTGCGGCTTGGCGGCCAGGGTGCGATCTCCGGCATGG
CGAATTTCGTACCTCGCGAAGTCAAGCTGATGGCGGAGGAAGGCAAAGACGATTCTCGCATCGAGGATTTCGTGGACGAA
CTGCTGAAATTTCCGGTGACCGCTGCCGTGAAAGTGATGGTAGCTCACCTGACGTCGGATGAAATCTGGCTTGCGGTTCG
CCCACCACTCGTTTCGATATCCGGCGAAGGGCAGGCGCAACTCGCTCTTGTGTTCGACACCCTTTTCCGCTCGAAGGCGG
CATAG

Upstream 100 bases:

>100_bases
ACTGCGTCGACATGGGTGTAGCGAGGCAGTGTACAATCACCTCTTTACATCTAACATGTTAGTTTGCTACATCTGATCCA
TTCTTTGGGAGGAAGCATAT

Downstream 100 bases:

>100_bases
GTCGGAGATGTTTCTGGGAGAGGCGATGGACGGAACCGACGAGCAGCCGACACTGCGGGAAAAGGCGTATGAGAGCTTCA
CACGCCACCTTCTTGCGCGT

Product: putative dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MTQKFGLSVALATPFDSNGDIAIEAMIEQARRSLAAGCSSVTLFGTTGEGSSIGTRERERVLASLLDSGIAAKQIIVGVL
VDAAEDAAMQAGHALSKGARNILLAPPSYFKNVSDDGVFQWFSAVFTILGDKARDIIVYNIPSVTMVPLSVSLIGRLRTA
FPDIVTGVKDSSGDWPFTEALLKAHGDLVILVGDERHLAKGVRLGGQGAISGMANFVPREVKLMAEEGKDDSRIEDFVDE
LLKFPVTAAVKVMVAHLTSDEIWLAVRPPLVSISGEGQAQLALVFDTLFRSKAA

Sequences:

>Translated_294_residues
MTQKFGLSVALATPFDSNGDIAIEAMIEQARRSLAAGCSSVTLFGTTGEGSSIGTRERERVLASLLDSGIAAKQIIVGVL
VDAAEDAAMQAGHALSKGARNILLAPPSYFKNVSDDGVFQWFSAVFTILGDKARDIIVYNIPSVTMVPLSVSLIGRLRTA
FPDIVTGVKDSSGDWPFTEALLKAHGDLVILVGDERHLAKGVRLGGQGAISGMANFVPREVKLMAEEGKDDSRIEDFVDE
LLKFPVTAAVKVMVAHLTSDEIWLAVRPPLVSISGEGQAQLALVFDTLFRSKAA
>Mature_293_residues
TQKFGLSVALATPFDSNGDIAIEAMIEQARRSLAAGCSSVTLFGTTGEGSSIGTRERERVLASLLDSGIAAKQIIVGVLV
DAAEDAAMQAGHALSKGARNILLAPPSYFKNVSDDGVFQWFSAVFTILGDKARDIIVYNIPSVTMVPLSVSLIGRLRTAF
PDIVTGVKDSSGDWPFTEALLKAHGDLVILVGDERHLAKGVRLGGQGAISGMANFVPREVKLMAEEGKDDSRIEDFVDEL
LKFPVTAAVKVMVAHLTSDEIWLAVRPPLVSISGEGQAQLALVFDTLFRSKAA

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Escherichia coli, GI1788823, Length=224, Percent_Identity=27.6785714285714, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786463, Length=241, Percent_Identity=25.7261410788382, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082415, Length=224, Percent_Identity=25.8928571428571, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31242; Mature: 31111

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKFGLSVALATPFDSNGDIAIEAMIEQARRSLAAGCSSVTLFGTTGEGSSIGTRERER
CCCCCCCEEEEECCCCCCCCEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHH
VLASLLDSGIAAKQIIVGVLVDAAEDAAMQAGHALSKGARNILLAPPSYFKNVSDDGVFQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHCCCCCCHHHH
WFSAVFTILGDKARDIIVYNIPSVTMVPLSVSLIGRLRTAFPDIVTGVKDSSGDWPFTEA
HHHHHHHHHCCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
LLKAHGDLVILVGDERHLAKGVRLGGQGAISGMANFVPREVKLMAEEGKDDSRIEDFVDE
HHHCCCCEEEEECCCHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHH
LLKFPVTAAVKVMVAHLTSDEIWLAVRPPLVSISGEGQAQLALVFDTLFRSKAA
HHHCCHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCEEHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQKFGLSVALATPFDSNGDIAIEAMIEQARRSLAAGCSSVTLFGTTGEGSSIGTRERER
CCCCCCEEEEECCCCCCCCEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHH
VLASLLDSGIAAKQIIVGVLVDAAEDAAMQAGHALSKGARNILLAPPSYFKNVSDDGVFQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHCCCCCCHHHH
WFSAVFTILGDKARDIIVYNIPSVTMVPLSVSLIGRLRTAFPDIVTGVKDSSGDWPFTEA
HHHHHHHHHCCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
LLKAHGDLVILVGDERHLAKGVRLGGQGAISGMANFVPREVKLMAEEGKDDSRIEDFVDE
HHHCCCCEEEEECCCHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHH
LLKFPVTAAVKVMVAHLTSDEIWLAVRPPLVSISGEGQAQLALVFDTLFRSKAA
HHHCCHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA