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The map label for this gene is plsC [H]

Identifier: 115352807

GI number: 115352807

Start: 3036822

End: 3037586

Strand: Direct

Name: plsC [H]

Synonym: Bamb_2756

Alternate gene names: 115352807

Gene position: 3036822-3037586 (Clockwise)

Preceding gene: 115352806

Following gene: 115352808

Centisome position: 85.39

GC content: 64.71

Gene sequence:

>765_bases
ATGCGCTTCGTCCGCTCCCTGCTGCTGCTGATCTACTTCATCCTGTACACGGTGCCGTACGCCACCGCGTGCTTCATCGC
GTTCCCGTTCATGCGTCCCGACGCGCGCTACTGGATGGCGGCCGGCTGGTGCAAGTCGACGCTGTGGGTCGTGCGCTGGC
TGAACGGCATCCACTACCGGATCGAAGGGATGGAAAACCTGCCCGACGGCCCGGCCGTGCTGCTGTCGAAGCACCAGTCG
GCGTGGGAGACGCTCGCGTTTCCGGCGCTGATGCCGAAGCCGCTGTGCTACGTGTTCAAGCGCGAACTGCTCTACGTGCC
GTTCTTCGGCTGGGCGCTCGGGCTGCTGCACATGGTCAACATCGACCGCAAGGAAGGCAAGAACGCGTTCACGTCGGTGA
TCCGCCAGGGCAAGAAGCGCCTGTCGGAAGGCGCGTGGATGATCATGTTCCCGGAAGGCACGCGCACGCCGGTCGGCAAG
CAGGGCAAATACAAGACGGGCGGCGCGCGCTTCGCGATCGAAACCAATACGCCGGTCGTGCCGATCGCGCACAATGCAGG
TCGTGTGTGGCCGCGCAATTCGTTCACGAAATTCCCGGGCGTCGTCACCGTGTCGATCGGCAAGCCGATTCCCGTCGACG
GCAAGACGCCCGACGTATTGAACTCGCAGGTCGAAGCCTGGATCGAAGCGGAAATGCGCCGCATCGATCCCGATGCGTAT
CGCCAGCCGGGCAACGCCGGCACGCGCGATGCCGCGCGCGTCTGA

Upstream 100 bases:

>100_bases
GTCCACGACGACCTGCGCGCGTTCGCGCTCGACTTCCTTTCACACGAACACGAGTGATGCGGCCGCCGCGCGCATCCTCC
TTACCACCAGACCCACGCCG

Downstream 100 bases:

>100_bases
ATCACCCGGATTGCAGCCGTTGCGAACGACGAAACGAAGCGAACTGATGAAAAAGCGTCCGCGGCCACGGCCTGCCGTCG
TGGCCCTCGATCATCGCCAG

Product: phospholipid/glycerol acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MRFVRSLLLLIYFILYTVPYATACFIAFPFMRPDARYWMAAGWCKSTLWVVRWLNGIHYRIEGMENLPDGPAVLLSKHQS
AWETLAFPALMPKPLCYVFKRELLYVPFFGWALGLLHMVNIDRKEGKNAFTSVIRQGKKRLSEGAWMIMFPEGTRTPVGK
QGKYKTGGARFAIETNTPVVPIAHNAGRVWPRNSFTKFPGVVTVSIGKPIPVDGKTPDVLNSQVEAWIEAEMRRIDPDAY
RQPGNAGTRDAARV

Sequences:

>Translated_254_residues
MRFVRSLLLLIYFILYTVPYATACFIAFPFMRPDARYWMAAGWCKSTLWVVRWLNGIHYRIEGMENLPDGPAVLLSKHQS
AWETLAFPALMPKPLCYVFKRELLYVPFFGWALGLLHMVNIDRKEGKNAFTSVIRQGKKRLSEGAWMIMFPEGTRTPVGK
QGKYKTGGARFAIETNTPVVPIAHNAGRVWPRNSFTKFPGVVTVSIGKPIPVDGKTPDVLNSQVEAWIEAEMRRIDPDAY
RQPGNAGTRDAARV
>Mature_254_residues
MRFVRSLLLLIYFILYTVPYATACFIAFPFMRPDARYWMAAGWCKSTLWVVRWLNGIHYRIEGMENLPDGPAVLLSKHQS
AWETLAFPALMPKPLCYVFKRELLYVPFFGWALGLLHMVNIDRKEGKNAFTSVIRQGKKRLSEGAWMIMFPEGTRTPVGK
QGKYKTGGARFAIETNTPVVPIAHNAGRVWPRNSFTKFPGVVTVSIGKPIPVDGKTPDVLNSQVEAWIEAEMRRIDPDAY
RQPGNAGTRDAARV

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=208, Percent_Identity=27.8846153846154, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI15100175, Length=208, Percent_Identity=27.8846153846154, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI6041665, Length=174, Percent_Identity=27.5862068965517, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17564032, Length=271, Percent_Identity=26.5682656826568, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320151, Length=176, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281364648, Length=223, Percent_Identity=27.8026905829596, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24582856, Length=223, Percent_Identity=27.8026905829596, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24582854, Length=223, Percent_Identity=27.8026905829596, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24641614, Length=221, Percent_Identity=25.3393665158371, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641612, Length=221, Percent_Identity=25.3393665158371, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28780; Mature: 28780

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVRSLLLLIYFILYTVPYATACFIAFPFMRPDARYWMAAGWCKSTLWVVRWLNGIHYR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
IEGMENLPDGPAVLLSKHQSAWETLAFPALMPKPLCYVFKRELLYVPFFGWALGLLHMVN
EECCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHC
IDRKEGKNAFTSVIRQGKKRLSEGAWMIMFPEGTRTPVGKQGKYKTGGARFAIETNTPVV
CCHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCEE
PIAHNAGRVWPRNSFTKFPGVVTVSIGKPIPVDGKTPDVLNSQVEAWIEAEMRRIDPDAY
EEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHH
RQPGNAGTRDAARV
CCCCCCCCCHHCCC
>Mature Secondary Structure
MRFVRSLLLLIYFILYTVPYATACFIAFPFMRPDARYWMAAGWCKSTLWVVRWLNGIHYR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
IEGMENLPDGPAVLLSKHQSAWETLAFPALMPKPLCYVFKRELLYVPFFGWALGLLHMVN
EECCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHC
IDRKEGKNAFTSVIRQGKKRLSEGAWMIMFPEGTRTPVGKQGKYKTGGARFAIETNTPVV
CCHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCEE
PIAHNAGRVWPRNSFTKFPGVVTVSIGKPIPVDGKTPDVLNSQVEAWIEAEMRRIDPDAY
EEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHH
RQPGNAGTRDAARV
CCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685; 7812434 [H]