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The map label for this gene is panC

Identifier: 115352540

GI number: 115352540

Start: 2749766

End: 2750605

Strand: Direct

Name: panC

Synonym: Bamb_2489

Alternate gene names: 115352540

Gene position: 2749766-2750605 (Clockwise)

Preceding gene: 115352539

Following gene: 115352541

Centisome position: 77.32

GC content: 68.33

Gene sequence:

>840_bases
ATGAAAGTCATCAGCTCGATCCAGGAACTGCGCGACCAGTTGCGCGGCCAGAACCGCACGGCGTTCGTGCCGACGATGGG
CAACCTGCACGAAGGTCACCTGTCGCTGATGCGCCTCGCGCGCCAGCACGGCGACCCGGTCGTGGCGAGCATCTTCGTCA
ACCGGCTGCAGTTCGGCCCGAACGAGGATTTCGACAAATATCCGCGCACGCTGCAGGACGACATCGAGAAGCTGCAGAAG
GAAAACGTCTACGTGCTGTTCGCGCCGACCGAGCGCGACATGTACCCGGAGCCGCAGGAGTACCGCGTGCTGCCGCCGGA
CGACCTCGGCGGGATCCTCGAGGGCGAGTTCCGCCCCGGCTTCTTCGCCGGCGTGTGCACGGTCGTCACGAAGCTGATGT
CCTGCGTGCAGCCGCGCGTCGCCGTGTTCGGCAAGAAGGACTACCAGCAGCTGATGATCGTGCGCCGGATGTGCCAGCAG
CTCGCGCTGCCGGTCGACATCATCGCGGCCGAGACCGTGCGCGACGAGGACGGCCTCGCGCTGTCGTCGCGCAACCGCTA
CCTGACGACCGACGAGCGCAAGGAAGCGCCCGAACTCGCGAAAACACTGCAGCGCGTGCGCGACGGCGTGCTCGGCGGCG
AACGCGACCTCGGCAAGCTCGAGCAGACCGCGCGCGCGCACCTGGCCGAGCGCGGCTGGGCGCCCGACTACATCTCGATC
CGCCGCCGCGCGAACCTGATCGCGCCGAGCGCCGCCGAGCTCGAAGCCGGCGAGCCGCTCGTCGTGCTCGCGGCCGCGAA
GCTCGGCGCGACGCGCCTGATCGACAACCTGGAAATCTGA

Upstream 100 bases:

>100_bases
CGCCCGATGCGCCGCCCGCGCGCCGGCGTTCTCCGCTTCGACCCCGACGCCGCTGTTGCGGCGCCAACGCGCGCATGCGC
GAGGAACCCGCTACCCGATC

Downstream 100 bases:

>100_bases
CGGGCCGCCCGCCCTCGCCTCTCACGCATCACGGAGATACCATGCAGCGCCACATGCTCAAATCGAAGATCCACCGCGCG
GCCGTCACGCACTGCGAGCT

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKVISSIQELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQDDIEKLQK
ENVYVLFAPTERDMYPEPQEYRVLPPDDLGGILEGEFRPGFFAGVCTVVTKLMSCVQPRVAVFGKKDYQQLMIVRRMCQQ
LALPVDIIAAETVRDEDGLALSSRNRYLTTDERKEAPELAKTLQRVRDGVLGGERDLGKLEQTARAHLAERGWAPDYISI
RRRANLIAPSAAELEAGEPLVVLAAAKLGATRLIDNLEI

Sequences:

>Translated_279_residues
MKVISSIQELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQDDIEKLQK
ENVYVLFAPTERDMYPEPQEYRVLPPDDLGGILEGEFRPGFFAGVCTVVTKLMSCVQPRVAVFGKKDYQQLMIVRRMCQQ
LALPVDIIAAETVRDEDGLALSSRNRYLTTDERKEAPELAKTLQRVRDGVLGGERDLGKLEQTARAHLAERGWAPDYISI
RRRANLIAPSAAELEAGEPLVVLAAAKLGATRLIDNLEI
>Mature_279_residues
MKVISSIQELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQDDIEKLQK
ENVYVLFAPTERDMYPEPQEYRVLPPDDLGGILEGEFRPGFFAGVCTVVTKLMSCVQPRVAVFGKKDYQQLMIVRRMCQQ
LALPVDIIAAETVRDEDGLALSSRNRYLTTDERKEAPELAKTLQRVRDGVLGGERDLGKLEQTARAHLAERGWAPDYISI
RRRANLIAPSAAELEAGEPLVVLAAAKLGATRLIDNLEI

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=283, Percent_Identity=45.2296819787986, Blast_Score=227, Evalue=5e-61,
Organism=Saccharomyces cerevisiae, GI6322046, Length=299, Percent_Identity=37.7926421404682, Blast_Score=164, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 31364; Mature: 31364

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVISSIQELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGP
CHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
NEDFDKYPRTLQDDIEKLQKENVYVLFAPTERDMYPEPQEYRVLPPDDLGGILEGEFRPG
CCCHHHCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCEECCCCCCCCCCCCCCCCC
FFAGVCTVVTKLMSCVQPRVAVFGKKDYQQLMIVRRMCQQLALPVDIIAAETVRDEDGLA
HHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCE
LSSRNRYLTTDERKEAPELAKTLQRVRDGVLGGERDLGKLEQTARAHLAERGWAPDYISI
ECCCCCCCCCCHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
RRRANLIAPSAAELEAGEPLVVLAAAKLGATRLIDNLEI
HHHHCCCCCCHHHCCCCCCEEEEEHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVISSIQELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGP
CHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
NEDFDKYPRTLQDDIEKLQKENVYVLFAPTERDMYPEPQEYRVLPPDDLGGILEGEFRPG
CCCHHHCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCEECCCCCCCCCCCCCCCCC
FFAGVCTVVTKLMSCVQPRVAVFGKKDYQQLMIVRRMCQQLALPVDIIAAETVRDEDGLA
HHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCE
LSSRNRYLTTDERKEAPELAKTLQRVRDGVLGGERDLGKLEQTARAHLAERGWAPDYISI
ECCCCCCCCCCHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
RRRANLIAPSAAELEAGEPLVVLAAAKLGATRLIDNLEI
HHHHCCCCCCHHHCCCCCCEEEEEHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA