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The map label for this gene is aspC [H]

Identifier: 115352300

GI number: 115352300

Start: 2482161

End: 2483360

Strand: Direct

Name: aspC [H]

Synonym: Bamb_2249

Alternate gene names: 115352300

Gene position: 2482161-2483360 (Clockwise)

Preceding gene: 115352294

Following gene: 115352302

Centisome position: 69.79

GC content: 66.08

Gene sequence:

>1200_bases
ATGTCGCTCTTCTCCGCTGTCCAGCTTGCTCCCCGCGACCCGATCCTGGGCCTGAACGAAGCCTTCAACGCCGATGCGCG
TCCGACCAAGGTCAACCTCGGCGTCGGTGTGTACACGAACGAAGAAGGCAAGATTCCGCTGCTGCGCGCCGTTCGCGAAG
CGGAAAAGGCGCGTGTCGACGCCGGCCTGCCGCGCGGCTACCTGCCGATCGACGGGATCGCCGCCTACGACGCAGCGGTG
CAGAAGCTGCTGCTCGGCAACGATTCGCCGCTGATCGCCGCAGGCCGCGTGGTCACCGCGCAGGCTCTGGGCGGCACGGG
CGCGCTGAAGATCGGCGCCGATTTCCTGCGCACCGTGAACCCGAACGCGAAGGTCGCGATCAGCGATCCGAGCTGGGAAA
ACCACCGCGCGCTGTTCGAAGCCGCCGGCTTCGAAGTCGTCGCGTATCCGTACTACGACGCCGCCACCAACGGCGTGAAC
TTCGACGGCATGCTGTCGGCGCTGAACGGCTATGCGGCAGGCACGATCGTCGTGCTGCACGCGTGCTGCCACAACCCGAC
CGGCGTGGACCTGACCGAAGCGCAATGGCAGCAGGTCGTCGACGTCGTCAAGGCGCGCAACCTCGTGCCGTTCCTCGACA
TGGCCTACCAGGGCTTCGGCGAGAACATCGAGGCAGATGCAGCGGCGGTGCGCCTGTTTGCCGCGGCCGACCTGAATGCA
TTCGTGTCGTCGTCGTTCTCGAAGTCGTTCTCGCTGTACGGCGAGCGCGTCGGCGCGCTGTCGATCATCACGTCGAGCAA
GGAAGAAGCGACGCGCGTGCTGTCGCAACTGAAGCGCGTGATCCGCACGAACTACTCGAACCCGCCGACCCATGGCGGCG
CCGTCGTCGCGGCCGTGCTCGCGTCGCCGGAACTGCACGCTGCATGGGTGCAGGAACTCGGCGAAATGCGCGACCGCATC
CGTGCGATGCGCAATGGCCTCGTCGAGCGCCTGAAGGCGAGCGGCGTGGATCGCGACTTCAGCTTCATCAACGCGCAGCG
CGGGATGTTCTCGTATTCGGGCCTGACCTCGGCGCAAGTCGATCGCCTGCGCGAAGAGTTCGGCATCTATGCAGTCGGCA
CGGGCCGCATCTGCGTGGCAGCGCTGAACACGCGCAACCTCGACGCGGTCGCCAATGCAGTCGCAGCAGTCCTGAAGTAA

Upstream 100 bases:

>100_bases
GCTGCTGCGCTTTCCGGCGCCGTGCCCGTTGGCGCGCGGTCCGCTGCGCCCGCCCCGCCGGCTGAAAGCCTGACCCTCTT
TTCACAACTGCCGAATCATC

Downstream 100 bases:

>100_bases
GTCGGCATCCGCGGGCGGCAGCCGTCACCGGCCCGCCCCGCCGAAACAAAAAACGCGCTCTCCGGAGCGCGTTTTTTTAT
GGCTTCGTGCATTGCCGGCG

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSLFSAVQLAPRDPILGLNEAFNADARPTKVNLGVGVYTNEEGKIPLLRAVREAEKARVDAGLPRGYLPIDGIAAYDAAV
QKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTVNPNAKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVN
FDGMLSALNGYAAGTIVVLHACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDMAYQGFGENIEADAAAVRLFAAADLNA
FVSSSFSKSFSLYGERVGALSIITSSKEEATRVLSQLKRVIRTNYSNPPTHGGAVVAAVLASPELHAAWVQELGEMRDRI
RAMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTSAQVDRLREEFGIYAVGTGRICVAALNTRNLDAVANAVAAVLK

Sequences:

>Translated_399_residues
MSLFSAVQLAPRDPILGLNEAFNADARPTKVNLGVGVYTNEEGKIPLLRAVREAEKARVDAGLPRGYLPIDGIAAYDAAV
QKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTVNPNAKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVN
FDGMLSALNGYAAGTIVVLHACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDMAYQGFGENIEADAAAVRLFAAADLNA
FVSSSFSKSFSLYGERVGALSIITSSKEEATRVLSQLKRVIRTNYSNPPTHGGAVVAAVLASPELHAAWVQELGEMRDRI
RAMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTSAQVDRLREEFGIYAVGTGRICVAALNTRNLDAVANAVAAVLK
>Mature_398_residues
SLFSAVQLAPRDPILGLNEAFNADARPTKVNLGVGVYTNEEGKIPLLRAVREAEKARVDAGLPRGYLPIDGIAAYDAAVQ
KLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTVNPNAKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVNF
DGMLSALNGYAAGTIVVLHACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDMAYQGFGENIEADAAAVRLFAAADLNAF
VSSSFSKSFSLYGERVGALSIITSSKEEATRVLSQLKRVIRTNYSNPPTHGGAVVAAVLASPELHAAWVQELGEMRDRIR
AMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTSAQVDRLREEFGIYAVGTGRICVAALNTRNLDAVANAVAAVLK

Specific function: Biosynthesis of Phe, Tyr, Asp and Leu. [C]

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=398, Percent_Identity=43.4673366834171, Blast_Score=340, Evalue=2e-93,
Organism=Homo sapiens, GI4504067, Length=401, Percent_Identity=43.8902743142145, Blast_Score=330, Evalue=2e-90,
Organism=Homo sapiens, GI117414139, Length=399, Percent_Identity=28.0701754385965, Blast_Score=176, Evalue=4e-44,
Organism=Escherichia coli, GI1790488, Length=399, Percent_Identity=55.1378446115288, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=47.979797979798, Blast_Score=398, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI71981858, Length=400, Percent_Identity=42, Blast_Score=350, Evalue=1e-96,
Organism=Caenorhabditis elegans, GI25147133, Length=399, Percent_Identity=42.1052631578947, Blast_Score=335, Evalue=2e-92,
Organism=Caenorhabditis elegans, GI17569539, Length=402, Percent_Identity=39.5522388059701, Blast_Score=301, Evalue=3e-82,
Organism=Caenorhabditis elegans, GI17569537, Length=398, Percent_Identity=33.9195979899498, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI25147136, Length=213, Percent_Identity=41.7840375586854, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17550384, Length=269, Percent_Identity=33.8289962825279, Blast_Score=177, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6323055, Length=408, Percent_Identity=38.2352941176471, Blast_Score=298, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6322743, Length=436, Percent_Identity=33.0275229357798, Blast_Score=244, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24580972, Length=400, Percent_Identity=42.75, Blast_Score=328, Evalue=5e-90,
Organism=Drosophila melanogaster, GI24580970, Length=400, Percent_Identity=42.75, Blast_Score=327, Evalue=7e-90,
Organism=Drosophila melanogaster, GI19920542, Length=393, Percent_Identity=42.4936386768448, Blast_Score=320, Evalue=2e-87,
Organism=Drosophila melanogaster, GI19922362, Length=401, Percent_Identity=39.4014962593516, Blast_Score=303, Evalue=1e-82,
Organism=Drosophila melanogaster, GI24654046, Length=401, Percent_Identity=39.4014962593516, Blast_Score=303, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42532; Mature: 42401

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFSAVQLAPRDPILGLNEAFNADARPTKVNLGVGVYTNEEGKIPLLRAVREAEKARVD
CCHHHHHHCCCCCCCCCCHHHCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHC
AGLPRGYLPIDGIAAYDAAVQKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTVN
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCEEEEECCCCCCEEHHCHHHHHHCC
PNAKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVNFDGMLSALNGYAAGTIVVLH
CCCEEEECCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHCCHHHHHHHHH
ACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDMAYQGFGENIEADAAAVRLFAAADLNA
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
FVSSSFSKSFSLYGERVGALSIITSSKEEATRVLSQLKRVIRTNYSNPPTHGGAVVAAVL
HHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ASPELHAAWVQELGEMRDRIRAMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTSAQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEECCCCCHHHH
DRLREEFGIYAVGTGRICVAALNTRNLDAVANAVAAVLK
HHHHHHHCEEEEECCCEEEEEECCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
SLFSAVQLAPRDPILGLNEAFNADARPTKVNLGVGVYTNEEGKIPLLRAVREAEKARVD
CHHHHHHCCCCCCCCCCHHHCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHC
AGLPRGYLPIDGIAAYDAAVQKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTVN
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCEEEEECCCCCCEEHHCHHHHHHCC
PNAKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVNFDGMLSALNGYAAGTIVVLH
CCCEEEECCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHCCHHHHHHHHH
ACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDMAYQGFGENIEADAAAVRLFAAADLNA
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
FVSSSFSKSFSLYGERVGALSIITSSKEEATRVLSQLKRVIRTNYSNPPTHGGAVVAAVL
HHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ASPELHAAWVQELGEMRDRIRAMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTSAQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEECCCCCHHHH
DRLREEFGIYAVGTGRICVAALNTRNLDAVANAVAAVLK
HHHHHHHCEEEEECCCEEEEEECCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8808952 [H]