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The map label for this gene is dapL [H]

Identifier: 115352112

GI number: 115352112

Start: 2262478

End: 2263641

Strand: Direct

Name: dapL [H]

Synonym: Bamb_2061

Alternate gene names: 115352112

Gene position: 2262478-2263641 (Clockwise)

Preceding gene: 115352106

Following gene: 115352113

Centisome position: 63.61

GC content: 68.81

Gene sequence:

>1164_bases
ATGCCCGGTGCCGGTACACCCGCTGCCAGCCTCAAACCGATCAGCTTCGGCATCGGCGAGCCCAAGCACCCGACGCCGGC
GCTGATCCGCGACGCCGTGGTGGCCGCGCTCGACGGTCTCGCGTCGTACCCGGCCACGGCCGGCTCGGACGCGCTGCGCA
CGTCGATCGCGCACTGGCTCGAACGCCGCTACGGGCTGCCGGCGCTCGATCCGGCCACGCAAGTGCTGCCCGTGTCGGGG
TCGCGCGAGGCGCTGTTCTCGCTCGCGCAGACGGTGATCGACTCGCGCGCGAGCGCGGACGGCAAGAAGGCGATCGTACT
CTGTCCGAATCCGTTCTATCAAATTTACGAAGGCGCGGCGCTGCTGGCCGGTGCCGAACCCTATTTCGCGAACAGCGACC
CGGCGCGCAACTTCGCTTGTGACTATGCGGCCGTGCCCGACGAGGTGTGGGCGCGCACCCAGCTGCTGTACGTGTGCTCG
CCGGGCAACCCGACGGGCGCCGTGCTGACGCTCGACGACTGGCGCGAGCTGTTCGCGCTGTCCGACCGCCACGGTTTCGT
GATCGCGTCCGACGAGTGCTATTCGGAAATCTATTTCGACGAAGCGGCGCCGCCGCTCGGCGGCCTCGAGGCCGCGCACC
GCCTCGGCCGCGGCTTCGAACGGCTCGTGATGCTGTCGAGCCTGTCCAAGCGCTCGAACGTGCCGGGCATGCGCTCGGGT
TTCGTCGCCGGCGACGCCGCGCTGCTCAAGAAATTCCTGCTGTATCGCACGTACCACGGTGCGGCGCTGTCGCCGGTCTG
GCAGCACGCGAGCATCGCCGCGTGGAACGACGAGGCGCACGTGCGCGAGAACCGCGCGCTGTACCTGCAGAAGTTCAACA
CGGTCACGCCGATGCTGGCCGACGTGATCGACGTGAAGCTGCCCGACGCCGCGTTCTACCTGTGGGCCAACGTCGCGCGC
ACCGGGCTGTCGGACACCGAGTTCGCCCGCCGCCTGTACGCCGACTATAATGTGACGGTTCTGCCCGGCTCGTACCTGGC
GCGCGACGCGCACGGCACGAATCCAGGCCGCGATTTCATCCGGATCGCGCTCGTCGCGGGCACCCCCGAATGCGTCGAGG
GCGCGCAACGCATCGTCGATTTCTGCCAAGCTCTCGCGCGGTAA

Upstream 100 bases:

>100_bases
GACGGCCGCTTCGCCCGTGAACCCTCGACTCGACTCGCTCCAGCCCTATCCCTTCGAAAAGCTGCGCGCCCTGTTCAAGG
ACGTGACGCCCGGTGCCGGT

Downstream 100 bases:

>100_bases
GACGTCCATCCCGATCAATTCCATTCCTCTCCTGCGAAAACGAACATGTCGCAACAACTTCAGCAAATCATCGATACCGC
CTGGGAAAACCGCGCCGAGC

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MPGAGTPAASLKPISFGIGEPKHPTPALIRDAVVAALDGLASYPATAGSDALRTSIAHWLERRYGLPALDPATQVLPVSG
SREALFSLAQTVIDSRASADGKKAIVLCPNPFYQIYEGAALLAGAEPYFANSDPARNFACDYAAVPDEVWARTQLLYVCS
PGNPTGAVLTLDDWRELFALSDRHGFVIASDECYSEIYFDEAAPPLGGLEAAHRLGRGFERLVMLSSLSKRSNVPGMRSG
FVAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWNDEAHVRENRALYLQKFNTVTPMLADVIDVKLPDAAFYLWANVAR
TGLSDTEFARRLYADYNVTVLPGSYLARDAHGTNPGRDFIRIALVAGTPECVEGAQRIVDFCQALAR

Sequences:

>Translated_387_residues
MPGAGTPAASLKPISFGIGEPKHPTPALIRDAVVAALDGLASYPATAGSDALRTSIAHWLERRYGLPALDPATQVLPVSG
SREALFSLAQTVIDSRASADGKKAIVLCPNPFYQIYEGAALLAGAEPYFANSDPARNFACDYAAVPDEVWARTQLLYVCS
PGNPTGAVLTLDDWRELFALSDRHGFVIASDECYSEIYFDEAAPPLGGLEAAHRLGRGFERLVMLSSLSKRSNVPGMRSG
FVAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWNDEAHVRENRALYLQKFNTVTPMLADVIDVKLPDAAFYLWANVAR
TGLSDTEFARRLYADYNVTVLPGSYLARDAHGTNPGRDFIRIALVAGTPECVEGAQRIVDFCQALAR
>Mature_386_residues
PGAGTPAASLKPISFGIGEPKHPTPALIRDAVVAALDGLASYPATAGSDALRTSIAHWLERRYGLPALDPATQVLPVSGS
REALFSLAQTVIDSRASADGKKAIVLCPNPFYQIYEGAALLAGAEPYFANSDPARNFACDYAAVPDEVWARTQLLYVCSP
GNPTGAVLTLDDWRELFALSDRHGFVIASDECYSEIYFDEAAPPLGGLEAAHRLGRGFERLVMLSSLSKRSNVPGMRSGF
VAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWNDEAHVRENRALYLQKFNTVTPMLADVIDVKLPDAAFYLWANVART
GLSDTEFARRLYADYNVTVLPGSYLARDAHGTNPGRDFIRIALVAGTPECVEGAQRIVDFCQALAR

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=275, Percent_Identity=25.4545454545455, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI169881279, Length=275, Percent_Identity=25.4545454545455, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI56713256, Length=400, Percent_Identity=21.75, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI56713254, Length=400, Percent_Identity=21.75, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788722, Length=337, Percent_Identity=26.7062314540059, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787909, Length=349, Percent_Identity=23.4957020057307, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786816, Length=348, Percent_Identity=24.4252873563218, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=392, Percent_Identity=23.7244897959184, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71994476, Length=267, Percent_Identity=24.3445692883895, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994472, Length=267, Percent_Identity=24.3445692883895, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 41805; Mature: 41674

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGAGTPAASLKPISFGIGEPKHPTPALIRDAVVAALDGLASYPATAGSDALRTSIAHWL
CCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ERRYGLPALDPATQVLPVSGSREALFSLAQTVIDSRASADGKKAIVLCPNPFYQIYEGAA
HHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHCCCE
LLAGAEPYFANSDPARNFACDYAAVPDEVWARTQLLYVCSPGNPTGAVLTLDDWRELFAL
EEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCEEEEEEECCCCCCEEEEEHHHHHHHHHH
SDRHGFVIASDECYSEIYFDEAAPPLGGLEAAHRLGRGFERLVMLSSLSKRSNVPGMRSG
CCCCCEEEECHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FVAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWNDEAHVRENRALYLQKFNTVTPMLA
CCCCHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEECCCHHHHCCCEEEEHHHCCHHHHHH
DVIDVKLPDAAFYLWANVARTGLSDTEFARRLYADYNVTVLPGSYLARDAHGTNPGRDFI
HHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCHHHHCCCCCCCCCCCEE
RIALVAGTPECVEGAQRIVDFCQALAR
EEEEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PGAGTPAASLKPISFGIGEPKHPTPALIRDAVVAALDGLASYPATAGSDALRTSIAHWL
CCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ERRYGLPALDPATQVLPVSGSREALFSLAQTVIDSRASADGKKAIVLCPNPFYQIYEGAA
HHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHCCCE
LLAGAEPYFANSDPARNFACDYAAVPDEVWARTQLLYVCSPGNPTGAVLTLDDWRELFAL
EEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCEEEEEEECCCCCCEEEEEHHHHHHHHHH
SDRHGFVIASDECYSEIYFDEAAPPLGGLEAAHRLGRGFERLVMLSSLSKRSNVPGMRSG
CCCCCEEEECHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FVAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWNDEAHVRENRALYLQKFNTVTPMLA
CCCCHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEECCCHHHHCCCEEEEHHHCCHHHHHH
DVIDVKLPDAAFYLWANVARTGLSDTEFARRLYADYNVTVLPGSYLARDAHGTNPGRDFI
HHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCHHHHCCCCCCCCCCCEE
RIALVAGTPECVEGAQRIVDFCQALAR
EEEEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA