Click here to switch to the map view.

The map label for this gene is emrY [H]

Identifier: 115351820

GI number: 115351820

Start: 1955736

End: 1957292

Strand: Direct

Name: emrY [H]

Synonym: Bamb_1769

Alternate gene names: 115351820

Gene position: 1955736-1957292 (Clockwise)

Preceding gene: 115351819

Following gene: 115351821

Centisome position: 54.99

GC content: 66.54

Gene sequence:

>1557_bases
ATGAACGTCGCGCGCGGTCGCTCGCCGCTGTGGAGCCGCGCGAACCTGCGCGCGGATCTCTTCCCATGGGCGCTCGCGCT
CGTCACCGGCATCGACTACTTCGACAACGCAGTCTTCTCGTTCTTCGCGAGCTACATCGCAGGCGGCATCAACGCGTCGC
CCGACGAACTCGTGTGGTCATCCAGCGCCTATGCGGTCACGGCGGTGCTCGGCATCCTGCAGCAGCAATGGTGGGTCGAC
CGGCTCGGACATCGCCGCTACGTCGCCGGCTGCATGCTGATGTTCTCGTTCGGCGCGATCGCGGCGGCATTCGCCGACAC
GTCGCTCGAGCTCGCGTTCGCGCGCGCCTTCCAGGGCTACTTCATCGGCCCGATGATGGGTGCGTGCCGGATCCTGATCC
AGATCAGCTTCAAGCCGCAGGCGCGGCCGCCCGCCACGCGCGCGTTCCTGATCATGATCCTGCTCGGCAGCGCGCTCGCG
CCGATCGTCGGCGGGCTGCTCGTCGCGCATTCGACGTGGCGCGCGCTGTTCGCGTGCACGGCGCCTGCCGGCATCGCGTT
CGCGATCCTCGCCCTCCTCACGCTGCCCGATTCGGGCAGGACGCCCGACGACGTACGCGGCTCCGGACATTTCTGGCCGT
ACATCGTGTTCGCGCTCGCGCAAGGCGCGCTGCAGATCGTGCTGCAGCAGGTGCACTACCAGCTCTACAGCGGCTCGCCG
ATGCTGATCATGCTGACGTTCGTCGGCGTGGCCGCGCTCGCGTGGTTCGCCTATCACCAGTGGCACCATCCGACGCCCCT
CGTGCGGCTGCATGCGTTTCGCGAGCGCACGTTCCAGGTCGGATTGCTGCTGTACATGTTCTATTACTACGAGTCGACCG
GCTTCAGCTACCTGACTTCCCGCCTGCTCGAGGGCGGGCTCGGCTATCCGGTCGAGAACGCCGGACGCCTGGTCGGCACG
ATGTCGCTGATCTCGGCGACCGCGCTGTTCGCTTACCTGCGCTACGCGAAGCACGTCACGCACAAGAAATGGTTCGTGGT
ACCGGGTTTCGCGATCGCGATCGCCGCCGCGCTGTGGATGACGCGGATGACGCCGCAGGTCGGCGAGGCCGCGCTGATCG
GCCCGCTGCTGTTGCGCGGGCTCTTGCTGCTGTTCATCGTGCTGCCGGTCGCGAACCTGACGTTCCGCATCTTCGCGATC
GACGAATACACGCACGGCTACCGGCTGAAGAACATCGTGCGGCAACTCACGATCTCGTTCGCGACGTCATCGGTGATCAT
CGTCGAGCAGCACCGGCTGGCCGTGCATCAGACGCGGCTCGTCGAGCGCGCGAACGTGTTCGATCCGCTGTTCCAGCAGA
CCGTCGACGCGCTCGCGCGCAGCTATGCGGCAGCCGGCCATGCGCTGAACGACGCGCACGCCCTTGCGATCGCGTCGGTC
GCGCGGATGGTCGCGCAACAGGCGTCGTTCCTCGCGTCGCTCGACGGTTTCTATTTCCTCGCGGGCGTCGCGCTCGTCGG
CGGCCTCTTCGCGGCATGGCAAAAAGAGATCGATTGA

Upstream 100 bases:

>100_bases
TCGACTACATCGAGCGGCGGCTCGCGGGCGAAAATCCCGACGCGCTGATCGCGCAGCGGCAGGCCGAAGCCCGCACGCGC
CGCGCGCGCAAGGACCGGGA

Downstream 100 bases:

>100_bases
GTTAAAAGACAGGCTTTGGATCTTCCGCGCTGCCTCCATGCTTTCGAAACTGACCCGCTGGTTCGACGACCGCCGCCGCG
ACCGCGCGCTGCGCAGCCAT

Product: major facilitator transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MNVARGRSPLWSRANLRADLFPWALALVTGIDYFDNAVFSFFASYIAGGINASPDELVWSSSAYAVTAVLGILQQQWWVD
RLGHRRYVAGCMLMFSFGAIAAAFADTSLELAFARAFQGYFIGPMMGACRILIQISFKPQARPPATRAFLIMILLGSALA
PIVGGLLVAHSTWRALFACTAPAGIAFAILALLTLPDSGRTPDDVRGSGHFWPYIVFALAQGALQIVLQQVHYQLYSGSP
MLIMLTFVGVAALAWFAYHQWHHPTPLVRLHAFRERTFQVGLLLYMFYYYESTGFSYLTSRLLEGGLGYPVENAGRLVGT
MSLISATALFAYLRYAKHVTHKKWFVVPGFAIAIAAALWMTRMTPQVGEAALIGPLLLRGLLLLFIVLPVANLTFRIFAI
DEYTHGYRLKNIVRQLTISFATSSVIIVEQHRLAVHQTRLVERANVFDPLFQQTVDALARSYAAAGHALNDAHALAIASV
ARMVAQQASFLASLDGFYFLAGVALVGGLFAAWQKEID

Sequences:

>Translated_518_residues
MNVARGRSPLWSRANLRADLFPWALALVTGIDYFDNAVFSFFASYIAGGINASPDELVWSSSAYAVTAVLGILQQQWWVD
RLGHRRYVAGCMLMFSFGAIAAAFADTSLELAFARAFQGYFIGPMMGACRILIQISFKPQARPPATRAFLIMILLGSALA
PIVGGLLVAHSTWRALFACTAPAGIAFAILALLTLPDSGRTPDDVRGSGHFWPYIVFALAQGALQIVLQQVHYQLYSGSP
MLIMLTFVGVAALAWFAYHQWHHPTPLVRLHAFRERTFQVGLLLYMFYYYESTGFSYLTSRLLEGGLGYPVENAGRLVGT
MSLISATALFAYLRYAKHVTHKKWFVVPGFAIAIAAALWMTRMTPQVGEAALIGPLLLRGLLLLFIVLPVANLTFRIFAI
DEYTHGYRLKNIVRQLTISFATSSVIIVEQHRLAVHQTRLVERANVFDPLFQQTVDALARSYAAAGHALNDAHALAIASV
ARMVAQQASFLASLDGFYFLAGVALVGGLFAAWQKEID
>Mature_518_residues
MNVARGRSPLWSRANLRADLFPWALALVTGIDYFDNAVFSFFASYIAGGINASPDELVWSSSAYAVTAVLGILQQQWWVD
RLGHRRYVAGCMLMFSFGAIAAAFADTSLELAFARAFQGYFIGPMMGACRILIQISFKPQARPPATRAFLIMILLGSALA
PIVGGLLVAHSTWRALFACTAPAGIAFAILALLTLPDSGRTPDDVRGSGHFWPYIVFALAQGALQIVLQQVHYQLYSGSP
MLIMLTFVGVAALAWFAYHQWHHPTPLVRLHAFRERTFQVGLLLYMFYYYESTGFSYLTSRLLEGGLGYPVENAGRLVGT
MSLISATALFAYLRYAKHVTHKKWFVVPGFAIAIAAALWMTRMTPQVGEAALIGPLLLRGLLLLFIVLPVANLTFRIFAI
DEYTHGYRLKNIVRQLTISFATSSVIIVEQHRLAVHQTRLVERANVFDPLFQQTVDALARSYAAAGHALNDAHALAIASV
ARMVAQQASFLASLDGFYFLAGVALVGGLFAAWQKEID

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1788710, Length=454, Percent_Identity=22.4669603524229, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1789042, Length=488, Percent_Identity=22.1311475409836, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790195, Length=431, Percent_Identity=22.737819025522, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI87081983, Length=265, Percent_Identity=24.5283018867925, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 56958; Mature: 56958

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVARGRSPLWSRANLRADLFPWALALVTGIDYFDNAVFSFFASYIAGGINASPDELVWS
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEC
SSAYAVTAVLGILQQQWWVDRLGHRRYVAGCMLMFSFGAIAAAFADTSLELAFARAFQGY
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
FIGPMMGACRILIQISFKPQARPPATRAFLIMILLGSALAPIVGGLLVAHSTWRALFACT
CHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APAGIAFAILALLTLPDSGRTPDDVRGSGHFWPYIVFALAQGALQIVLQQVHYQLYSGSP
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MLIMLTFVGVAALAWFAYHQWHHPTPLVRLHAFRERTFQVGLLLYMFYYYESTGFSYLTS
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RLLEGGLGYPVENAGRLVGTMSLISATALFAYLRYAKHVTHKKWFVVPGFAIAIAAALWM
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHH
TRMTPQVGEAALIGPLLLRGLLLLFIVLPVANLTFRIFAIDEYTHGYRLKNIVRQLTISF
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHH
ATSSVIIVEQHRLAVHQTRLVERANVFDPLFQQTVDALARSYAAAGHALNDAHALAIASV
HCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ARMVAQQASFLASLDGFYFLAGVALVGGLFAAWQKEID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNVARGRSPLWSRANLRADLFPWALALVTGIDYFDNAVFSFFASYIAGGINASPDELVWS
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEC
SSAYAVTAVLGILQQQWWVDRLGHRRYVAGCMLMFSFGAIAAAFADTSLELAFARAFQGY
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
FIGPMMGACRILIQISFKPQARPPATRAFLIMILLGSALAPIVGGLLVAHSTWRALFACT
CHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APAGIAFAILALLTLPDSGRTPDDVRGSGHFWPYIVFALAQGALQIVLQQVHYQLYSGSP
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MLIMLTFVGVAALAWFAYHQWHHPTPLVRLHAFRERTFQVGLLLYMFYYYESTGFSYLTS
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RLLEGGLGYPVENAGRLVGTMSLISATALFAYLRYAKHVTHKKWFVVPGFAIAIAAALWM
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHH
TRMTPQVGEAALIGPLLLRGLLLLFIVLPVANLTFRIFAIDEYTHGYRLKNIVRQLTISF
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHH
ATSSVIIVEQHRLAVHQTRLVERANVFDPLFQQTVDALARSYAAAGHALNDAHALAIASV
HCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ARMVAQQASFLASLDGFYFLAGVALVGGLFAAWQKEID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]