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The map label for this gene is blh [H]

Identifier: 115351721

GI number: 115351721

Start: 1844696

End: 1845565

Strand: Direct

Name: blh [H]

Synonym: Bamb_1669

Alternate gene names: 115351721

Gene position: 1844696-1845565 (Clockwise)

Preceding gene: 115351715

Following gene: 115351722

Centisome position: 51.87

GC content: 70.34

Gene sequence:

>870_bases
ATGCTGTCGGTCGAAGGCTTTTTCGACCCGGCGACCCACACCGTCAGCTATCTGCTGCTCGATACCGCGAGCCGCGCGTG
CGCGCTGATCGACAGCGTGCTCGACTACGACCCGAAGTCCGGACGCACGCGCACCGCCAGCGCCGACCGGCTGATCGCCC
GCGTCGCCGAACTCGGCGCGACCGTGCACTGGCTGCTGGAAACGCACGTGCACGCCGACCACCTGTCGGCCGCGCCGTAC
GTGAAGGCGCACGTCGGCGGCCGGATCGCGATCGGTTCGCACGTGCGCCGCGTGCAGCACGTGTTCGGCACGCTGTTCAA
CGCCGGCCCCGGCTTCGCGCAGGACGGCAGCCAGTTCGATCGCCTGCTCGACGACGGCGACACGCTCGCGCTCGGCGCGC
TGACGATCCGCGCGCTGCATACGCCGGGCCATACACCCGCCTGCCTGACCTACTGCGTCGACGATGCGACGCAGCGCGCG
GCATTCGTCGGCGACACGCTGTTCATGCCCGACTACGGCACCGCCCGCTGCGACTTCCCCGGCGGCGACGCACGCACGCT
GTACCGCTCGATCGCACGGGTGCTGGGCCTGCCGCCCGACACGCGCCTGTACCTGTGCCACGACTACCAGCCGGGCGGCC
GCGACGTGCAGTTCGTGACGACGGTCGCCGAGCAGCGCCGCGCGAACGTGCACGTGAAGGACGGCGTGACCGAAGACGAT
TTCGTCGCGATGCGCACCGCGCGCGACGCGACGCTCGACATGCCCGTGCTGATGCTGCCGTCCGTGCAGGTCAACATGCG
CGCCGGCCACCTGCCCGAGCCCGAAAACAACGGCGTGCGCTACCTGAAGATCCCGCTCGACGCGATCTGA

Upstream 100 bases:

>100_bases
TCGACCCGCCTCGCGGCGCGGATTGGCACGCTTCTTGAACATGGGATTGCCGATTGCCTATGCAGAACCCGATCGAGGAC
ATCCCGTGAGCCATGCCCCC

Downstream 100 bases:

>100_bases
GCCGCCGCCCCGACCGGAGAACCCCGACATGACCATCCGCCCGCTGACCGACCTGCTGTCGGTCTCGCCCCAGATCGCCG
CGACCGACCTGCCCGCGCTG

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MLSVEGFFDPATHTVSYLLLDTASRACALIDSVLDYDPKSGRTRTASADRLIARVAELGATVHWLLETHVHADHLSAAPY
VKAHVGGRIAIGSHVRRVQHVFGTLFNAGPGFAQDGSQFDRLLDDGDTLALGALTIRALHTPGHTPACLTYCVDDATQRA
AFVGDTLFMPDYGTARCDFPGGDARTLYRSIARVLGLPPDTRLYLCHDYQPGGRDVQFVTTVAEQRRANVHVKDGVTEDD
FVAMRTARDATLDMPVLMLPSVQVNMRAGHLPEPENNGVRYLKIPLDAI

Sequences:

>Translated_289_residues
MLSVEGFFDPATHTVSYLLLDTASRACALIDSVLDYDPKSGRTRTASADRLIARVAELGATVHWLLETHVHADHLSAAPY
VKAHVGGRIAIGSHVRRVQHVFGTLFNAGPGFAQDGSQFDRLLDDGDTLALGALTIRALHTPGHTPACLTYCVDDATQRA
AFVGDTLFMPDYGTARCDFPGGDARTLYRSIARVLGLPPDTRLYLCHDYQPGGRDVQFVTTVAEQRRANVHVKDGVTEDD
FVAMRTARDATLDMPVLMLPSVQVNMRAGHLPEPENNGVRYLKIPLDAI
>Mature_289_residues
MLSVEGFFDPATHTVSYLLLDTASRACALIDSVLDYDPKSGRTRTASADRLIARVAELGATVHWLLETHVHADHLSAAPY
VKAHVGGRIAIGSHVRRVQHVFGTLFNAGPGFAQDGSQFDRLLDDGDTLALGALTIRALHTPGHTPACLTYCVDDATQRA
AFVGDTLFMPDYGTARCDFPGGDARTLYRSIARVLGLPPDTRLYLCHDYQPGGRDVQFVTTVAEQRRANVHVKDGVTEDD
FVAMRTARDATLDMPVLMLPSVQVNMRAGHLPEPENNGVRYLKIPLDAI

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=264, Percent_Identity=30.3030303030303, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17538952, Length=263, Percent_Identity=28.1368821292776, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI221330176, Length=264, Percent_Identity=29.9242424242424, Blast_Score=109, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 31476; Mature: 31476

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVEGFFDPATHTVSYLLLDTASRACALIDSVLDYDPKSGRTRTASADRLIARVAELGA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCC
TVHWLLETHVHADHLSAAPYVKAHVGGRIAIGSHVRRVQHVFGTLFNAGPGFAQDGSQFD
HHEEHHHHHHCHHHCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
RLLDDGDTLALGALTIRALHTPGHTPACLTYCVDDATQRAAFVGDTLFMPDYGTARCDFP
HHHCCCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCEECCCC
GGDARTLYRSIARVLGLPPDTRLYLCHDYQPGGRDVQFVTTVAEQRRANVHVKDGVTEDD
CCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCH
FVAMRTARDATLDMPVLMLPSVQVNMRAGHLPEPENNGVRYLKIPLDAI
HEEEECCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MLSVEGFFDPATHTVSYLLLDTASRACALIDSVLDYDPKSGRTRTASADRLIARVAELGA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCC
TVHWLLETHVHADHLSAAPYVKAHVGGRIAIGSHVRRVQHVFGTLFNAGPGFAQDGSQFD
HHEEHHHHHHCHHHCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
RLLDDGDTLALGALTIRALHTPGHTPACLTYCVDDATQRAAFVGDTLFMPDYGTARCDFP
HHHCCCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCEECCCC
GGDARTLYRSIARVLGLPPDTRLYLCHDYQPGGRDVQFVTTVAEQRRANVHVKDGVTEDD
CCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCH
FVAMRTARDATLDMPVLMLPSVQVNMRAGHLPEPENNGVRYLKIPLDAI
HEEEECCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]