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The map label for this gene is fhuB [H]

Identifier: 115351586

GI number: 115351586

Start: 1683869

End: 1685962

Strand: Direct

Name: fhuB [H]

Synonym: Bamb_1533

Alternate gene names: 115351586

Gene position: 1683869-1685962 (Clockwise)

Preceding gene: 115351585

Following gene: 115351587

Centisome position: 47.35

GC content: 75.12

Gene sequence:

>2094_bases
ATGACGACGGTCGCGGGGCGCCAGCGGCTCGCGGCGAGCGGGCAGCGCACGGTATCCGGCCGCCGCGCCGGTGCGATCGC
GCTCGGCCTCGTCGTGCTGATCGCCGTGCTGGCGGTGCTGCGCGTCGCGCCGGACCTGCGCGTGTGGTGGAGCGCCGTGC
CGGGCAGCGACGCCGCCGCGCTCGCGGGCGTGTTCCTGTTCGATCTCAACCTGCCGCGCGTCGCGGCCGCGCTCGTCGCG
GGCGGCTGTCTCGGCATCGCGGGCGCGCTGTTCCAGTCGCTCACGCGCAATCCGCTCGCGTCGCCCGATCTGCTCGGCGT
GACGGGCGGCGCGCAGCTCGGCCTGCTCGCGGCGATGCTGGTGCCGGCGCTCGCTGGTGTCGCATCGGTGCCGCTGCTGT
TCGTCTGCGGGCTGATCGCGGCCGCGTGCGCGATCGTCGCGGCCGGCGGCTGGCGCGCGACGCCGTTGCGGCTCGTGCTC
GCGGGCAGCGTGTGCATGCTGCTGTTCGCGGCGCTGTCGACGCTCGTGCTCGCGTTCTTCGAGCAGAACATCGCGGGCGC
CGCGCTGTGGACCAACGGCAGTCTCTATCAACCGGGCGCGACCGGGCTCGCGCTCGCCGCGCGCTGGCTCGTCGTGCCGC
TGCTTGCGCTGCCGTTCGTGATCCGGCCGCTGAATCCGCTCGCGCTCGGCGACGAGGCGGCGGCCACGGCCGGCGTGCGT
GTCGATGCGACGCGACTCGCCGCGACGATCGTCGCGGTCGCGTTCACGAGCGTCGCGGTCAGCATCGCGGGCCCGCTGTC
GTATGTCGGGCTCGTCGCGCCGAACCTGCTGCGCCAGGTGCGCGGGGCCCGCGCGGCGCGGCTCGGCGTGCTGGTGCCGC
TGTCGGCGCTCGCGGGCGGTGCGCTCGTGCTGGTGACCGACAGCGCGGTGCTCGGGTCGGGCCTCGACGCGACGCTGTCG
ACGGGTGTCGCGATCGCACTCGTCGGCACGCCGCTGATGCTCGCGATGATCCGGCGCGGCGCCGCGTGGTCGGGCGTGCT
GCATGCGCAAGCCGAACGCGCGGCCGGCAGCGGCTCGACGCGCGTGGTCGGCTGGCTCGAAGGGCTCGGCTGGCCGTTGC
GCACCGTGCTGTTCGTCGCGGCCGGCGTGCTCGCGGTGTTCGTCGGCGTATCGGCCGGCCCCGAATGGTTGTCGCCCGCG
CGCTGGTTGGCCGCGCTGTCGGGCCACGATGCGCTCGCGCGGATGCTGATCGACCTGCGCATGCCGCGGCTGCTGTGCGC
GCTCCTCGCGGGCGCGCTGCTGGCCGTGAGCGGCGTCGCGATGCAGAGCGTCGTGCGCAACCCGCTCGCCGGCCCCGAAG
TGCTCGGCGTCACGCAGGGCGCGGGGCTCGTCACGCTGTTCGCATTGTCGACGTGGCCGCTGATGGGCCACGTGACGCTT
GCCGCGGCCGCGTTGACCGGCGGTGCGCTGTCGCTCGCGATCACGCTCGCGCTGAATCATCGGCATCGTTACGCACCGCT
CGCGGTCGCGCTGACCGGCATCGCGATCGGCGCGCTATGGACCACGCTCGCGCAATGGCTGATCACGCAGGAAAGCGTGC
AGCCCGCGCGCTTCGTCGTCTGGCTCGTCGGCGGCACGTACGGCCGCAGCTGGGGCGAGGTGACGATGCTGCTGCCGTGG
TGCGTGCTCGCGGTCCCCGTATTCGCGTGGCTCGCGCGGCCGCTCGACATGCTCGCGCTCGGCGACGACCAGGCCGCCGC
GCTCGGGCTGCCGGTCGCCGCGTTGCGGCCGCTCGCGCTGACGATCGCGACGCTCGCGGCCTGCGCGGCCGTCGCGGCCG
TCGGGCCGGTCGGCTTCATCGGGCTGATGGCGCCGCACGTCGCGTCGATGCTCGGCGCACGCCGGCATCGCACACGGCTG
TGGCTCGCGGCCGCGTGCGGCGCGCTGATCCTCGGCCTCGCCGATCTGGCGGCACGCACGGTCGTCGCGCCGCGCGAAGT
GCCGGCCGGCGTGCTGACCGCGCTGATCGGCGCGCCGTATCTGCTCGGGCTGCTGATCGTCGAGGGGCGCCGCGCCCGGC
GCACGGGGCGATGA

Upstream 100 bases:

>100_bases
ATCCGCAGACGGGCGCGCCGATGTGCGTGCCGGCCTACGGGCCGCCGGCATCCGGCACGCCGCACGCGTTCGAGCACGCG
GTCGACCGGGATATCGCCGT

Downstream 100 bases:

>100_bases
CGCCCGCGCTCGACGGTGCATGCGCCACGCGCTTTTCCGCGTTCGCGCCGGAACCGTTCGCCGAGCATCTCGATGTCGTA
TGGCTCGGGATGCCCGACGA

Product: iron-hydroxamate transporter permease subunit

Products: ADP; phosphate; iron (III) hydroxamate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein B; Ferrichrome transport system permease protein fhuB; Ferrichrome uptake protein fhuB; Iron(III)-hydroxamate import system permease protein fhuB [H]

Number of amino acids: Translated: 697; Mature: 696

Protein sequence:

>697_residues
MTTVAGRQRLAASGQRTVSGRRAGAIALGLVVLIAVLAVLRVAPDLRVWWSAVPGSDAAALAGVFLFDLNLPRVAAALVA
GGCLGIAGALFQSLTRNPLASPDLLGVTGGAQLGLLAAMLVPALAGVASVPLLFVCGLIAAACAIVAAGGWRATPLRLVL
AGSVCMLLFAALSTLVLAFFEQNIAGAALWTNGSLYQPGATGLALAARWLVVPLLALPFVIRPLNPLALGDEAAATAGVR
VDATRLAATIVAVAFTSVAVSIAGPLSYVGLVAPNLLRQVRGARAARLGVLVPLSALAGGALVLVTDSAVLGSGLDATLS
TGVAIALVGTPLMLAMIRRGAAWSGVLHAQAERAAGSGSTRVVGWLEGLGWPLRTVLFVAAGVLAVFVGVSAGPEWLSPA
RWLAALSGHDALARMLIDLRMPRLLCALLAGALLAVSGVAMQSVVRNPLAGPEVLGVTQGAGLVTLFALSTWPLMGHVTL
AAAALTGGALSLAITLALNHRHRYAPLAVALTGIAIGALWTTLAQWLITQESVQPARFVVWLVGGTYGRSWGEVTMLLPW
CVLAVPVFAWLARPLDMLALGDDQAAALGLPVAALRPLALTIATLAACAAVAAVGPVGFIGLMAPHVASMLGARRHRTRL
WLAAACGALILGLADLAARTVVAPREVPAGVLTALIGAPYLLGLLIVEGRRARRTGR

Sequences:

>Translated_697_residues
MTTVAGRQRLAASGQRTVSGRRAGAIALGLVVLIAVLAVLRVAPDLRVWWSAVPGSDAAALAGVFLFDLNLPRVAAALVA
GGCLGIAGALFQSLTRNPLASPDLLGVTGGAQLGLLAAMLVPALAGVASVPLLFVCGLIAAACAIVAAGGWRATPLRLVL
AGSVCMLLFAALSTLVLAFFEQNIAGAALWTNGSLYQPGATGLALAARWLVVPLLALPFVIRPLNPLALGDEAAATAGVR
VDATRLAATIVAVAFTSVAVSIAGPLSYVGLVAPNLLRQVRGARAARLGVLVPLSALAGGALVLVTDSAVLGSGLDATLS
TGVAIALVGTPLMLAMIRRGAAWSGVLHAQAERAAGSGSTRVVGWLEGLGWPLRTVLFVAAGVLAVFVGVSAGPEWLSPA
RWLAALSGHDALARMLIDLRMPRLLCALLAGALLAVSGVAMQSVVRNPLAGPEVLGVTQGAGLVTLFALSTWPLMGHVTL
AAAALTGGALSLAITLALNHRHRYAPLAVALTGIAIGALWTTLAQWLITQESVQPARFVVWLVGGTYGRSWGEVTMLLPW
CVLAVPVFAWLARPLDMLALGDDQAAALGLPVAALRPLALTIATLAACAAVAAVGPVGFIGLMAPHVASMLGARRHRTRL
WLAAACGALILGLADLAARTVVAPREVPAGVLTALIGAPYLLGLLIVEGRRARRTGR
>Mature_696_residues
TTVAGRQRLAASGQRTVSGRRAGAIALGLVVLIAVLAVLRVAPDLRVWWSAVPGSDAAALAGVFLFDLNLPRVAAALVAG
GCLGIAGALFQSLTRNPLASPDLLGVTGGAQLGLLAAMLVPALAGVASVPLLFVCGLIAAACAIVAAGGWRATPLRLVLA
GSVCMLLFAALSTLVLAFFEQNIAGAALWTNGSLYQPGATGLALAARWLVVPLLALPFVIRPLNPLALGDEAAATAGVRV
DATRLAATIVAVAFTSVAVSIAGPLSYVGLVAPNLLRQVRGARAARLGVLVPLSALAGGALVLVTDSAVLGSGLDATLST
GVAIALVGTPLMLAMIRRGAAWSGVLHAQAERAAGSGSTRVVGWLEGLGWPLRTVLFVAAGVLAVFVGVSAGPEWLSPAR
WLAALSGHDALARMLIDLRMPRLLCALLAGALLAVSGVAMQSVVRNPLAGPEVLGVTQGAGLVTLFALSTWPLMGHVTLA
AAALTGGALSLAITLALNHRHRYAPLAVALTGIAIGALWTTLAQWLITQESVQPARFVVWLVGGTYGRSWGEVTMLLPWC
VLAVPVFAWLARPLDMLALGDDQAAALGLPVAALRPLALTIATLAACAAVAAVGPVGFIGLMAPHVASMLGARRHRTRLW
LAAACGALILGLADLAARTVVAPREVPAGVLTALIGAPYLLGLLIVEGRRARRTGR

Specific function: Part of the ABC transporter complex fhuCDB involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786347, Length=632, Percent_Identity=32.2784810126582, Blast_Score=191, Evalue=9e-50,
Organism=Escherichia coli, GI1790740, Length=292, Percent_Identity=40.7534246575342, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1788004, Length=309, Percent_Identity=36.2459546925566, Blast_Score=125, Evalue=9e-30,
Organism=Escherichia coli, GI1786804, Length=322, Percent_Identity=34.7826086956522, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790741, Length=266, Percent_Identity=36.8421052631579, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1786805, Length=311, Percent_Identity=32.7974276527331, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522
- InterPro:   IPR006311 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 70742; Mature: 70611

Theoretical pI: Translated: 11.83; Mature: 11.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVAGRQRLAASGQRTVSGRRAGAIALGLVVLIAVLAVLRVAPDLRVWWSAVPGSDAAA
CCCCCCHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCHHH
LAGVFLFDLNLPRVAAALVAGGCLGIAGALFQSLTRNPLASPDLLGVTGGAQLGLLAAML
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHH
VPALAGVASVPLLFVCGLIAAACAIVAAGGWRATPLRLVLAGSVCMLLFAALSTLVLAFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EQNIAGAALWTNGSLYQPGATGLALAARWLVVPLLALPFVIRPLNPLALGDEAAATAGVR
HHCCCCEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCE
VDATRLAATIVAVAFTSVAVSIAGPLSYVGLVAPNLLRQVRGARAARLGVLVPLSALAGG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
ALVLVTDSAVLGSGLDATLSTGVAIALVGTPLMLAMIRRGAAWSGVLHAQAERAAGSGST
EEEEEECCHHHCCCCCHHHHCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
RVVGWLEGLGWPLRTVLFVAAGVLAVFVGVSAGPEWLSPARWLAALSGHDALARMLIDLR
EEEEHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHCCHHHHHHHHHHHH
MPRLLCALLAGALLAVSGVAMQSVVRNPLAGPEVLGVTQGAGLVTLFALSTWPLMGHVTL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHCCHHHHHHH
AAAALTGGALSLAITLALNHRHRYAPLAVALTGIAIGALWTTLAQWLITQESVQPARFVV
HHHHHCCCHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
WLVGGTYGRSWGEVTMLLPWCVLAVPVFAWLARPLDMLALGDDQAAALGLPVAALRPLAL
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCHHHHCCCHHHHHHHHH
TIATLAACAAVAAVGPVGFIGLMAPHVASMLGARRHRTRLWLAAACGALILGLADLAART
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVAPREVPAGVLTALIGAPYLLGLLIVEGRRARRTGR
HCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCC
>Mature Secondary Structure 
TTVAGRQRLAASGQRTVSGRRAGAIALGLVVLIAVLAVLRVAPDLRVWWSAVPGSDAAA
CCCCCHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCHHH
LAGVFLFDLNLPRVAAALVAGGCLGIAGALFQSLTRNPLASPDLLGVTGGAQLGLLAAML
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHH
VPALAGVASVPLLFVCGLIAAACAIVAAGGWRATPLRLVLAGSVCMLLFAALSTLVLAFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EQNIAGAALWTNGSLYQPGATGLALAARWLVVPLLALPFVIRPLNPLALGDEAAATAGVR
HHCCCCEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCE
VDATRLAATIVAVAFTSVAVSIAGPLSYVGLVAPNLLRQVRGARAARLGVLVPLSALAGG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
ALVLVTDSAVLGSGLDATLSTGVAIALVGTPLMLAMIRRGAAWSGVLHAQAERAAGSGST
EEEEEECCHHHCCCCCHHHHCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
RVVGWLEGLGWPLRTVLFVAAGVLAVFVGVSAGPEWLSPARWLAALSGHDALARMLIDLR
EEEEHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHCCHHHHHHHHHHHH
MPRLLCALLAGALLAVSGVAMQSVVRNPLAGPEVLGVTQGAGLVTLFALSTWPLMGHVTL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHCCHHHHHHH
AAAALTGGALSLAITLALNHRHRYAPLAVALTGIAIGALWTTLAQWLITQESVQPARFVV
HHHHHCCCHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
WLVGGTYGRSWGEVTMLLPWCVLAVPVFAWLARPLDMLALGDDQAAALGLPVAALRPLAL
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCHHHHCCCHHHHHHHHH
TIATLAACAAVAAVGPVGFIGLMAPHVASMLGARRHRTRLWLAAACGALILGLADLAART
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVAPREVPAGVLTALIGAPYLLGLLIVEGRRARRTGR
HCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron (III) hydroxamate [Periplasm]; H2O [C]

Specific reaction: ATP + iron (III) hydroxamate [Periplasm] + H2O = ADP + phosphate + iron (III) hydroxamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258 [H]