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The map label for this gene is maeB [H]

Identifier: 115350586

GI number: 115350586

Start: 596936

End: 599236

Strand: Direct

Name: maeB [H]

Synonym: Bamb_0532

Alternate gene names: 115350586

Gene position: 596936-599236 (Clockwise)

Preceding gene: 115350582

Following gene: 115350587

Centisome position: 16.78

GC content: 66.19

Gene sequence:

>2301_bases
ATGTCGACCCAAGCCTCCTCCAAAGCCAAGCTCCGCGAAGCCGCTCTCGATTATCACGAATTCCCGACTCCCGGGAAGAT
CGCGATCGCCCCGACCAAGCAGATGATCAACCAGCGCGACCTCGCGCTCGCGTATTCGCCGGGCGTCGCGTATGCGTGCG
AGGAGATCGTCGAGAACCCGCTGAACGCCGCGCGCTTCACCGCGCGCAGCAACCTGGTCGGCGTGGTCACGAACGGCACC
GCGGTGCTCGGGCTCGGCAACATCGGCCCGCTCGCGTCGAAGCCGGTGATGGAAGGCAAGGCCGTCCTGTTCAAGAAGTT
CGCCGGCATCGACGTGTTCGACATCGAACTGAACGAGTCGGACCCGCACAAGCTGGTCGACGTGATCGCCGCGCTGGAGC
CGACCTTCGGCGGGATCAACCTGGAAGACATCAAGGCGCCGGACTGCTTCATCGTCGAGCGCGAAGCGCGCAAGCGGATG
AAGATCCCGGTGTTCCACGACGACCAGCACGGCACCGCGATCGTCGTGGCCGCGGCCGTCACGAACGGCCTGAAGGTCGT
CGGCAAGGACATCAAGAAGGTGAAGCTCGTCGCGTCGGGCGCCGGCGCGGCCGCGCTCGCGTGTCTGGACCTGCTCGTCG
ACATCGGGCTGCCGATCGAGAACATCCTGGTGACCGACCTGGCCGGCGTGGTCTACAAGGGACGCACCGAGCTGATGGAT
CCGGACAAGGAGCGTTTCGCGCGCGAAACCGAAGCCCGCACGCTGGCCGAGGTGATCGAAGGCGCGGACATCTTCCTCGG
CCTGTCGGCCGCGGGCGTGCTGAAGCAGGAGATGGTGAAGGGCATGGCCGAGCGCCCGCTGATCCTCGCGCTCGCGAACC
CGACGCCGGAAATCCTGCCGGAACTGGCGCTCGAAGTGCGCCCCGACGCCGTGCTGGCCACCGGCCGCACCGACTATCCG
AACCAGGTCAACAACGTCCTGTGCTTCCCGTTCATCTTCCGCGGCGCGCTCGACGTCGGCGCGACGACGATCACGCGTGA
AATGGAGATCGCGGCCGTCAACGCGATCGCCGAGCTCGCGCAGCAGGAGCAGAGCGACATCGTCGCGACCGCGTACGGCA
TTCAGGACCTGTCGTTCGGGCCCGACTACCTGATTCCGAAGCCGTTCGATCCGCGCCTGATCGTCAAGATCGCGCCGGCC
GTCGCGCAGGCCGCGATGGACGGCGGCGTCGCGACGCGCCCGATCGAGGACATGGAAGCGTACCGCGTTCACCTGCAGCA
GTTCGTGTATCACAGCGGCACGACGATGAAGCCGATCTTCCAGATCGCGCGCGCCGCGCCGGCAGAGAAAAAGCGCGTGG
TGTTCGCGGAAGGCGAGGAAGAGCGCGTGTTGCGCGCCGTTCAGATCATCGTCGACGAGAAGCTCGCGACGCCGATCCTG
ATCGGCCGCCCGTCGGTGATCGAGCACCGTATCCAGCGCTACGGCCTGCGCCTCACGCCGGGCACCGACTTCACGGTCGT
CAACACCGAGCACGACGAACGCTACCGCGACTTCTGGCAGACGTACTACAAGATGATGTCGCGCAAGGGCATCAGCGAGC
AGCTGGCCCGCGTGGAAATGCGCCGCCGCACGACGCTGATCGGCTCGATGCTGGTGAAGAAGGGCGAAGCGGACGGGATG
ATCTGCGGCACGATCAGCACGACGCACCGCCACCTGCACTTCATCGACCAGGTGATCGGCAAGCGCCCGGGCTGCAGCGT
GTACGCGGCGATGAACGGCCTCGTGCTGCCGGGTCGCCAGATTTTCCTGGTCGATACGCACGTGAACGTCGATCCGACGC
CGGAGGAACTCGCCGAGATCACGATCATGGCTGCGGAAGAAGTGCGCCGGTTCGGCATCGAGCCGAAGGTCGCGCTGGTG
TCGCACTCGAATTTCGGCACGAGCAACGCCCCTTCGGCGAAGAAGATGCGCGATACGCTCGCGATCCTGCAGGAACGCGC
GCCGGAGCTGAAGGTCGACGGCGAAATGCACGGCGACGTGGCGCTCGACGCGGCGCTGCGCAAGGAAATCCTGCCGGAAT
CGACGCTCGAAGGCGACGCGAACCTGCTGATCCTGCCGAACATCGACGCCGCGAACATCGCGTACAACCTGCTGAAGACG
GCCGCCGGCAACAACATCGCGATCGGGCCGATCCTGCTCGGCGCGGCGCAGCCGGTGCACGTGCTGACCGAATCGGCGAC
GGTTCGCCGCATCGTCAACATGGCGGCGCTGCTGGTCGCCGACGTGAACGCCGCACGCTGA

Upstream 100 bases:

>100_bases
TTTTGTCGCGGCTGTCGCACCCGAATCGCCGGTCTGGCGGCCTTGGATTGGCGCTACAATGCCGTCGAACAGTTATTCTA
ATCCGCCCGCCAAGAGACAC

Downstream 100 bases:

>100_bases
GCCGGAACGAACGCGCGGCGCCGGTCAACCGGTGCCGTGCGTCGGGCGAAATTGTAAACAAAAGCAAAAAGAGGCGTGCC
CGCAAGGGGCACGCCGTCAG

Product: malic enzyme

Products: NA

Alternate protein names: NADP-ME [H]

Number of amino acids: Translated: 766; Mature: 765

Protein sequence:

>766_residues
MSTQASSKAKLREAALDYHEFPTPGKIAIAPTKQMINQRDLALAYSPGVAYACEEIVENPLNAARFTARSNLVGVVTNGT
AVLGLGNIGPLASKPVMEGKAVLFKKFAGIDVFDIELNESDPHKLVDVIAALEPTFGGINLEDIKAPDCFIVEREARKRM
KIPVFHDDQHGTAIVVAAAVTNGLKVVGKDIKKVKLVASGAGAAALACLDLLVDIGLPIENILVTDLAGVVYKGRTELMD
PDKERFARETEARTLAEVIEGADIFLGLSAAGVLKQEMVKGMAERPLILALANPTPEILPELALEVRPDAVLATGRTDYP
NQVNNVLCFPFIFRGALDVGATTITREMEIAAVNAIAELAQQEQSDIVATAYGIQDLSFGPDYLIPKPFDPRLIVKIAPA
VAQAAMDGGVATRPIEDMEAYRVHLQQFVYHSGTTMKPIFQIARAAPAEKKRVVFAEGEEERVLRAVQIIVDEKLATPIL
IGRPSVIEHRIQRYGLRLTPGTDFTVVNTEHDERYRDFWQTYYKMMSRKGISEQLARVEMRRRTTLIGSMLVKKGEADGM
ICGTISTTHRHLHFIDQVIGKRPGCSVYAAMNGLVLPGRQIFLVDTHVNVDPTPEELAEITIMAAEEVRRFGIEPKVALV
SHSNFGTSNAPSAKKMRDTLAILQERAPELKVDGEMHGDVALDAALRKEILPESTLEGDANLLILPNIDAANIAYNLLKT
AAGNNIAIGPILLGAAQPVHVLTESATVRRIVNMAALLVADVNAAR

Sequences:

>Translated_766_residues
MSTQASSKAKLREAALDYHEFPTPGKIAIAPTKQMINQRDLALAYSPGVAYACEEIVENPLNAARFTARSNLVGVVTNGT
AVLGLGNIGPLASKPVMEGKAVLFKKFAGIDVFDIELNESDPHKLVDVIAALEPTFGGINLEDIKAPDCFIVEREARKRM
KIPVFHDDQHGTAIVVAAAVTNGLKVVGKDIKKVKLVASGAGAAALACLDLLVDIGLPIENILVTDLAGVVYKGRTELMD
PDKERFARETEARTLAEVIEGADIFLGLSAAGVLKQEMVKGMAERPLILALANPTPEILPELALEVRPDAVLATGRTDYP
NQVNNVLCFPFIFRGALDVGATTITREMEIAAVNAIAELAQQEQSDIVATAYGIQDLSFGPDYLIPKPFDPRLIVKIAPA
VAQAAMDGGVATRPIEDMEAYRVHLQQFVYHSGTTMKPIFQIARAAPAEKKRVVFAEGEEERVLRAVQIIVDEKLATPIL
IGRPSVIEHRIQRYGLRLTPGTDFTVVNTEHDERYRDFWQTYYKMMSRKGISEQLARVEMRRRTTLIGSMLVKKGEADGM
ICGTISTTHRHLHFIDQVIGKRPGCSVYAAMNGLVLPGRQIFLVDTHVNVDPTPEELAEITIMAAEEVRRFGIEPKVALV
SHSNFGTSNAPSAKKMRDTLAILQERAPELKVDGEMHGDVALDAALRKEILPESTLEGDANLLILPNIDAANIAYNLLKT
AAGNNIAIGPILLGAAQPVHVLTESATVRRIVNMAALLVADVNAAR
>Mature_765_residues
STQASSKAKLREAALDYHEFPTPGKIAIAPTKQMINQRDLALAYSPGVAYACEEIVENPLNAARFTARSNLVGVVTNGTA
VLGLGNIGPLASKPVMEGKAVLFKKFAGIDVFDIELNESDPHKLVDVIAALEPTFGGINLEDIKAPDCFIVEREARKRMK
IPVFHDDQHGTAIVVAAAVTNGLKVVGKDIKKVKLVASGAGAAALACLDLLVDIGLPIENILVTDLAGVVYKGRTELMDP
DKERFARETEARTLAEVIEGADIFLGLSAAGVLKQEMVKGMAERPLILALANPTPEILPELALEVRPDAVLATGRTDYPN
QVNNVLCFPFIFRGALDVGATTITREMEIAAVNAIAELAQQEQSDIVATAYGIQDLSFGPDYLIPKPFDPRLIVKIAPAV
AQAAMDGGVATRPIEDMEAYRVHLQQFVYHSGTTMKPIFQIARAAPAEKKRVVFAEGEEERVLRAVQIIVDEKLATPILI
GRPSVIEHRIQRYGLRLTPGTDFTVVNTEHDERYRDFWQTYYKMMSRKGISEQLARVEMRRRTTLIGSMLVKKGEADGMI
CGTISTTHRHLHFIDQVIGKRPGCSVYAAMNGLVLPGRQIFLVDTHVNVDPTPEELAEITIMAAEEVRRFGIEPKVALVS
HSNFGTSNAPSAKKMRDTLAILQERAPELKVDGEMHGDVALDAALRKEILPESTLEGDANLLILPNIDAANIAYNLLKTA
AGNNIAIGPILLGAAQPVHVLTESATVRRIVNMAALLVADVNAAR

Specific function: Unknown

COG id: COG0281

COG function: function code C; Malic enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Homo sapiens, GI62420882, Length=352, Percent_Identity=28.6931818181818, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI62420880, Length=352, Percent_Identity=28.6931818181818, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI239049447, Length=352, Percent_Identity=28.6931818181818, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI4505143, Length=343, Percent_Identity=26.8221574344023, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI4505145, Length=369, Percent_Identity=26.8292682926829, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1788806, Length=753, Percent_Identity=61.7529880478088, Blast_Score=966, Evalue=0.0,
Organism=Escherichia coli, GI1788635, Length=322, Percent_Identity=32.9192546583851, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1788800, Length=326, Percent_Identity=31.2883435582822, Blast_Score=149, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17537199, Length=464, Percent_Identity=25.2155172413793, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322823, Length=239, Percent_Identity=30.9623430962343, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281362672, Length=425, Percent_Identity=27.0588235294118, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21356279, Length=425, Percent_Identity=27.0588235294118, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281362674, Length=425, Percent_Identity=27.0588235294118, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI78707242, Length=408, Percent_Identity=25.9803921568627, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI78707238, Length=408, Percent_Identity=25.9803921568627, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI78707240, Length=349, Percent_Identity=26.3610315186246, Blast_Score=77, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24646388, Length=349, Percent_Identity=28.3667621776504, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24646386, Length=349, Percent_Identity=28.3667621776504, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015884
- InterPro:   IPR012301
- InterPro:   IPR012302
- InterPro:   IPR012188
- InterPro:   IPR016040
- InterPro:   IPR002505 [H]

Pfam domain/function: PF00390 malic; PF03949 Malic_M; PF01515 PTA_PTB [H]

EC number: =1.1.1.40 [H]

Molecular weight: Translated: 83093; Mature: 82962

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQASSKAKLREAALDYHEFPTPGKIAIAPTKQMINQRDLALAYSPGVAYACEEIVENP
CCCCCCHHHHHHHHHHHHHCCCCCCEEEECCHHHHCCCCCEEEEECCCHHHHHHHHHHCC
LNAARFTARSNLVGVVTNGTAVLGLGNIGPLASKPVMEGKAVLFKKFAGIDVFDIELNES
CHHHHHHHCCCEEEEEECCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCC
DPHKLVDVIAALEPTFGGINLEDIKAPDCFIVEREARKRMKIPVFHDDQHGTAIVVAAAV
CHHHHHHHHHHHCCCCCCCCHHHCCCCCEEEEEHHHHCCCCCCEEECCCCCCEEEEEEHH
TNGLKVVGKDIKKVKLVASGAGAAALACLDLLVDIGLPIENILVTDLAGVVYKGRTELMD
HCCHHHHCCCHHEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHCCC
PDKERFARETEARTLAEVIEGADIFLGLSAAGVLKQEMVKGMAERPLILALANPTPEILP
CCHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHH
ELALEVRPDAVLATGRTDYPNQVNNVLCFPFIFRGALDVGATTITREMEIAAVNAIAELA
HHHHHCCCCEEEECCCCCCCHHHCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QQEQSDIVATAYGIQDLSFGPDYLIPKPFDPRLIVKIAPAVAQAAMDGGVATRPIEDMEA
HHHHCCEEEEEECCEECCCCCCCCCCCCCCCEEEEEECHHHHHHHHCCCCCCCCHHHHHH
YRVHLQQFVYHSGTTMKPIFQIARAAPAEKKRVVFAEGEEERVLRAVQIIVDEKLATPIL
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEE
IGRPSVIEHRIQRYGLRLTPGTDFTVVNTEHDERYRDFWQTYYKMMSRKGISEQLARVEM
ECCCHHHHHHHHHCCCEECCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RRRTTLIGSMLVKKGEADGMICGTISTTHRHLHFIDQVIGKRPGCSVYAAMNGLVLPGRQ
HHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCEEEEECCCEECCCCE
IFLVDTHVNVDPTPEELAEITIMAAEEVRRFGIEPKVALVSHSNFGTSNAPSAKKMRDTL
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHH
AILQERAPELKVDGEMHGDVALDAALRKEILPESTLEGDANLLILPNIDAANIAYNLLKT
HHHHHCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHH
AAGNNIAIGPILLGAAQPVHVLTESATVRRIVNMAALLVADVNAAR
CCCCCEEECCEEECCCCCHHHHHCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
STQASSKAKLREAALDYHEFPTPGKIAIAPTKQMINQRDLALAYSPGVAYACEEIVENP
CCCCCHHHHHHHHHHHHHCCCCCCEEEECCHHHHCCCCCEEEEECCCHHHHHHHHHHCC
LNAARFTARSNLVGVVTNGTAVLGLGNIGPLASKPVMEGKAVLFKKFAGIDVFDIELNES
CHHHHHHHCCCEEEEEECCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCC
DPHKLVDVIAALEPTFGGINLEDIKAPDCFIVEREARKRMKIPVFHDDQHGTAIVVAAAV
CHHHHHHHHHHHCCCCCCCCHHHCCCCCEEEEEHHHHCCCCCCEEECCCCCCEEEEEEHH
TNGLKVVGKDIKKVKLVASGAGAAALACLDLLVDIGLPIENILVTDLAGVVYKGRTELMD
HCCHHHHCCCHHEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHCCC
PDKERFARETEARTLAEVIEGADIFLGLSAAGVLKQEMVKGMAERPLILALANPTPEILP
CCHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHH
ELALEVRPDAVLATGRTDYPNQVNNVLCFPFIFRGALDVGATTITREMEIAAVNAIAELA
HHHHHCCCCEEEECCCCCCCHHHCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QQEQSDIVATAYGIQDLSFGPDYLIPKPFDPRLIVKIAPAVAQAAMDGGVATRPIEDMEA
HHHHCCEEEEEECCEECCCCCCCCCCCCCCCEEEEEECHHHHHHHHCCCCCCCCHHHHHH
YRVHLQQFVYHSGTTMKPIFQIARAAPAEKKRVVFAEGEEERVLRAVQIIVDEKLATPIL
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEE
IGRPSVIEHRIQRYGLRLTPGTDFTVVNTEHDERYRDFWQTYYKMMSRKGISEQLARVEM
ECCCHHHHHHHHHCCCEECCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RRRTTLIGSMLVKKGEADGMICGTISTTHRHLHFIDQVIGKRPGCSVYAAMNGLVLPGRQ
HHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCEEEEECCCEECCCCE
IFLVDTHVNVDPTPEELAEITIMAAEEVRRFGIEPKVALVSHSNFGTSNAPSAKKMRDTL
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHH
AILQERAPELKVDGEMHGDVALDAALRKEILPESTLEGDANLLILPNIDAANIAYNLLKT
HHHHHCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHH
AAGNNIAIGPILLGAAQPVHVLTESATVRRIVNMAALLVADVNAAR
CCCCCEEECCEEECCCCCHHHHHCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 36376 [H]