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The map label for this gene is potC

Identifier: 11499198

GI number: 11499198

Start: 1442044

End: 1442772

Strand: Reverse

Name: potC

Synonym: AF1606

Alternate gene names: 11499198

Gene position: 1442772-1442044 (Counterclockwise)

Preceding gene: 11499199

Following gene: 11499197

Centisome position: 66.23

GC content: 50.48

Gene sequence:

>729_bases
ATGATTCTGAGGGCTTTCACCATTGCAGTCTTCGCCTTCCTCTACATCCCCATCGTGATCATGATAGCCCTCTCCTTCTA
CGATGACGGCTTTACGCTGAGGAACTATCAGGCCCTTCTGGAGGACAGGGAGATTGTCAGCGCATTCTTCAACAGCATAG
GCGTCGCCTTGCTGTCCACCATCATCTCTGTAATTCTCGGAACACTCGCGGCTTACGCCTTCATGCGAGATCAGATCTCA
TTCAGCGCCCTTTTCTACCCTCCGATAATAATACCCGAAATCACGGAGGCCGTTTCGCTTTTGCTCTTTTTCATAGTTCT
CGGCTTCCCCCTCGGCTTTTACTCAGTCCTGATAGGCCACACCGCCTTCAACATAGCCTTCGTTTTCGTGATAGTTTCGG
CAAGAGGCGCTAACCTCAGAAGGGAGTTCGAGGAAGCCTCGTACATACTCGGAGCCAACGAGTTTCAGACCTTCAGGAAG
GTAACTCTGCCACTTCTCATGCCCGGAATAATCGCAGCTTCGCTCATAGCCTTCACTCTCTCATGGGACAACTTCATAAA
GACCGTATTCACCACCGGGCCGGGATTCGAGACTCTCCCGTTAATCATATGGTCTCAGGCCGCGAGAGGTGTTGTAAGCC
CTACAATAAACGCCCTCGCCTCTCTGATGATTGTAATCTCCCTTCTTCTGTCTTATATTTACGTCAGAATCACTGTGAGC
GAGAGGTAA

Upstream 100 bases:

>100_bases
ACCACAACTGGTGGAAGGGCTCTGCTCTCTCGGTCATTTACCTGGCTGTTGTGTTTGCCTTCACAGCTTACTATATAAAG
AGGGCGGGGAGGCTGGAGCT

Downstream 100 bases:

>100_bases
ATTATTTATTCAGCTTCCATCACTTCAATCTATGCCAAGACTGACGAGAAGGCGTTTTATCGGTCTTGCTGCTGGAGTGG
CGGGAATGACGCTTTTTGGA

Product: spermidine/putrescine ABC transporter, permease protein (potC)

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MILRAFTIAVFAFLYIPIVIMIALSFYDDGFTLRNYQALLEDREIVSAFFNSIGVALLSTIISVILGTLAAYAFMRDQIS
FSALFYPPIIIPEITEAVSLLLFFIVLGFPLGFYSVLIGHTAFNIAFVFVIVSARGANLRREFEEASYILGANEFQTFRK
VTLPLLMPGIIAASLIAFTLSWDNFIKTVFTTGPGFETLPLIIWSQAARGVVSPTINALASLMIVISLLLSYIYVRITVS
ER

Sequences:

>Translated_242_residues
MILRAFTIAVFAFLYIPIVIMIALSFYDDGFTLRNYQALLEDREIVSAFFNSIGVALLSTIISVILGTLAAYAFMRDQIS
FSALFYPPIIIPEITEAVSLLLFFIVLGFPLGFYSVLIGHTAFNIAFVFVIVSARGANLRREFEEASYILGANEFQTFRK
VTLPLLMPGIIAASLIAFTLSWDNFIKTVFTTGPGFETLPLIIWSQAARGVVSPTINALASLMIVISLLLSYIYVRITVS
ER
>Mature_242_residues
MILRAFTIAVFAFLYIPIVIMIALSFYDDGFTLRNYQALLEDREIVSAFFNSIGVALLSTIISVILGTLAAYAFMRDQIS
FSALFYPPIIIPEITEAVSLLLFFIVLGFPLGFYSVLIGHTAFNIAFVFVIVSARGANLRREFEEASYILGANEFQTFRK
VTLPLLMPGIIAASLIAFTLSWDNFIKTVFTTGPGFETLPLIIWSQAARGVVSPTINALASLMIVISLLLSYIYVRITVS
ER

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=206, Percent_Identity=37.378640776699, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1787081, Length=232, Percent_Identity=35.3448275862069, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787714, Length=230, Percent_Identity=36.5217391304348, Blast_Score=95, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 26854; Mature: 26854

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CC
>Mature Secondary Structure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CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]