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The map label for this gene is rfbF

Identifier: 11498742

GI number: 11498742

Start: 1017490

End: 1018215

Strand: Reverse

Name: rfbF

Synonym: AF1142

Alternate gene names: 11498742

Gene position: 1018215-1017490 (Counterclockwise)

Preceding gene: 11498744

Following gene: 11498741

Centisome position: 46.74

GC content: 45.87

Gene sequence:

>726_bases
ATGGAGGCAGTAATACTCGCTGCAGGTTTCGGTTCACGATTGGGTCATCACACTCGCGAAATCCCGAAAGCTCTCCTGAA
AATTGGGAAAAGACCGTTGATATACTACACGGTTCAGACTCTGATGGAGAACGGTATCAGGGATGTTGTAGTGGTTACCG
GACACAAAGGATACGTTTTGAGGGAGTATCTTTCGCAGTTCGACCTCAATTTCAAATTTGTCCACAACAGCCTTTACAAG
AAAACCAACAACATTTACAGCCTCTATCTGGCAATGGACCACGTGAGCAAGGGATTTTACATCCTGAACTCCGATGTTCT
CTTCCATCCCGGCATCTTTCGGGAACTGCACTCCTCCACGAAGGAGAACCTGATACTGTCCGTTGACACGTTCAAGGAGC
TTGGAGAGGAGGAGATGAAGGTCAAAATAGAGGATGGAGTTGTTAAAAGAATAAGCAAACAGCTCAACCCCTCAGAGGCT
GATGGAGAATACATAGGCATTGCAAGAGTTGAGGAAAACATCATCGACGACCTCTACAACCACGTTTCCAGAGTTATGGA
AAGGAAAGGGAGAAGAGTGTTCTATGAGGAGGCTTTTCAGTCAATGATGGATGACGGCATCGCTGTTTACTATGAAACAA
CAAAAGGGCTTCCGTGGATTGAAATAGACACCCCTGCGGACTTGATGAAGGCCAGATACGAAATCTACCCCAAAATCCAG
TTTTGA

Upstream 100 bases:

>100_bases
GAAAACCTCCGATAAACAAGTTCTGTCAGCAGATACTCCCATTTGATTTAAATCACCTCCTTATGGGTAATTTTAAATAA
CTCTCCTTTTAACATTTTTC

Downstream 100 bases:

>100_bases
GAAAAAGAAATATAGACCCATTTTTTACTTGAAGCATGGCAATCGGTTTTACCTTTACCGAGGAGCAGGAGGATATAAGG
AGAGCTGCAAGAGAGTTTGC

Product: glucose-1-phosphate cytidylyltransferase (rfbF)

Products: diphosphate; CDPglucose

Alternate protein names: Nucleotide Sugar-1-Phosphate Transferase; Nucleotidyltransferase Family Protein; Hemolysin Erythrocyte Lysis; Glucose-1-Phosphate Thymidylyltransferase; Sugar Nucleotidyltransferase; Glucose-1-Phosphate Cytidylyltransferase; UDP-N-Acetylglucosamine Pyrophosphorylase Related Protein; Aminotransferase Class I And II; CDP-Alcohol Phosphatidyltransferase; LicC Protein; Phosphoenolpyruvate Phosphomutase; Sugar Nucleotidyltransferase-Like Protein; Choline Kinase; Nucleoside-Diphosphate-Sugar Pyrophosphorylase; Glucose-1-P-Cytidylyltransferase; Nucleotidyl Transferase Superfamily; Sugar Metabolism Cluster Protein; Glucose-1-Phosphate Thymidylyltransferase-Like Protein; Hemolysin Erythrocyte Lysis Protein; LicC-Like Protein; Aminotransferase; ADP-Glucose Pyrophosphorylase; Glucose-1-Phosphate Thymidylyltransferase Related Protein; Choline/Ethanolamine Kinase Family Protein; CTPPhosphocholine Cytidylyltransferase; Choline/Ethanolamine Kinase; Nucleotidyl Transferase/Aminotransferase Classes I And II; Threonine-Phosphate Decarboxylase; 4-Diphosphocytidyl-2C-Methyl-D-Erythritolsynthas E; Nucleotidyl Transferase WchZ; Aminotransferase Class V; Transcription Regulator; Transferase; 2-Aminoethylphosphonate Aminotransferase; Cholinephosphate Cytidylyltransferase/Choline Kinase; Histidinol-Phosphate Aminotransferase; Sugar-Phosphate Nucleotide Transferase; Aminoglycoside Phosphotransferase Family Protein; Sugar-1-Phosphate Nucleotidyltransferase; Cholinephosphate Cytidylyltransferase; CTPInositol-1-Phosphate Cytidylyltransferase; Glucose-1-P Cytidylyltransferase; Nucleotidyl Transferase/Aminotransferase; Histidinol-Phosphate Aminotransferase HisC; Mannose-1-Phosphate Guanyltransferase; Sugar Nucleotidyltransferase-Like; Nucleotidyl Transferase/Aminotransferase Class V; Phosphoenolpyruvate Mutase

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MEAVILAAGFGSRLGHHTREIPKALLKIGKRPLIYYTVQTLMENGIRDVVVVTGHKGYVLREYLSQFDLNFKFVHNSLYK
KTNNIYSLYLAMDHVSKGFYILNSDVLFHPGIFRELHSSTKENLILSVDTFKELGEEEMKVKIEDGVVKRISKQLNPSEA
DGEYIGIARVEENIIDDLYNHVSRVMERKGRRVFYEEAFQSMMDDGIAVYYETTKGLPWIEIDTPADLMKARYEIYPKIQ
F

Sequences:

>Translated_241_residues
MEAVILAAGFGSRLGHHTREIPKALLKIGKRPLIYYTVQTLMENGIRDVVVVTGHKGYVLREYLSQFDLNFKFVHNSLYK
KTNNIYSLYLAMDHVSKGFYILNSDVLFHPGIFRELHSSTKENLILSVDTFKELGEEEMKVKIEDGVVKRISKQLNPSEA
DGEYIGIARVEENIIDDLYNHVSRVMERKGRRVFYEEAFQSMMDDGIAVYYETTKGLPWIEIDTPADLMKARYEIYPKIQ
F
>Mature_241_residues
MEAVILAAGFGSRLGHHTREIPKALLKIGKRPLIYYTVQTLMENGIRDVVVVTGHKGYVLREYLSQFDLNFKFVHNSLYK
KTNNIYSLYLAMDHVSKGFYILNSDVLFHPGIFRELHSSTKENLILSVDTFKELGEEEMKVKIEDGVVKRISKQLNPSEA
DGEYIGIARVEENIIDDLYNHVSRVMERKGRRVFYEEAFQSMMDDGIAVYYETTKGLPWIEIDTPADLMKARYEIYPKIQ
F

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1213

COG function: function code M; Predicted sugar nucleotidyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.33

Molecular weight: Translated: 27899; Mature: 27899

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAVILAAGFGSRLGHHTREIPKALLKIGKRPLIYYTVQTLMENGIRDVVVVTGHKGYVL
CCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCEEEEEECCCCHHH
REYLSQFDLNFKFVHNSLYKKTNNIYSLYLAMDHVSKGFYILNSDVLFHPGIFRELHSST
HHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEEEHHCCCEEEEECCEEECCHHHHHHHCCC
KENLILSVDTFKELGEEEMKVKIEDGVVKRISKQLNPSEADGEYIGIARVEENIIDDLYN
CCCEEEEEHHHHHCCHHHEEEEEHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHH
HVSRVMERKGRRVFYEEAFQSMMDDGIAVYYETTKGLPWIEIDTPADLMKARYEIYPKIQ
HHHHHHHHCCCEEHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHCCCCC
F
C
>Mature Secondary Structure
MEAVILAAGFGSRLGHHTREIPKALLKIGKRPLIYYTVQTLMENGIRDVVVVTGHKGYVL
CCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCEEEEEECCCCHHH
REYLSQFDLNFKFVHNSLYKKTNNIYSLYLAMDHVSKGFYILNSDVLFHPGIFRELHSST
HHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEEEHHCCCEEEEECCEEECCHHHHHHHCCC
KENLILSVDTFKELGEEEMKVKIEDGVVKRISKQLNPSEADGEYIGIARVEENIIDDLYN
CCCEEEEEHHHHHCCHHHEEEEEHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHH
HVSRVMERKGRRVFYEEAFQSMMDDGIAVYYETTKGLPWIEIDTPADLMKARYEIYPKIQ
HHHHHHHHCCCEEHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHCCCCC
F
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CTP; alpha-D-glucose 1-phosphate

Specific reaction: CTP + alpha-D-glucose 1-phosphate = diphosphate + CDP-glucose

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA