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The map label for this gene is fabG [H]

Identifier: 114800460

GI number: 114800460

Start: 3131673

End: 3132455

Strand: Direct

Name: fabG [H]

Synonym: HNE_2974

Alternate gene names: 114800460

Gene position: 3131673-3132455 (Clockwise)

Preceding gene: 114797417

Following gene: 114798367

Centisome position: 84.53

GC content: 63.35

Gene sequence:

>783_bases
ATGCAAATCACGAAAGATACTGCCGCCATCGTCACCGGGGGCGCTTCGGGCCTCGGCCAGGCCACTGCCCGCGCGCTCGC
CAAGGCCGGCGCCAAGGTTGCCATCTTCGACATCAACGAAGAAGCCGGCGAAGCGACCGCGAAGGAAATCGGCGGCATCT
TCTGCAATGTGAACATCATGGACGAGGCCTCCGCCGTGGCCGGCTTCGAGAAAGCCCGCGCCGCCCATGGCCAGGAGCGG
ATCACCGTTCACTGCGCGATGGCATCGAAAGGCGGCAAGACACTTTCCTGGGACAAGGAAAACGCCCGCTACAAACGCCT
CACCACCGAAGACTACGAATTCGGCGCCAAGGGCGTTCTGGTTGCGTCCTACCGCATCGCTTCGCTTTCGGCCGAGGGCA
TGGCGAACCTGCCCGAGCTGGAAGACGGCGAGCGCGGCGTGATCACGCTGACCGCCTCGGTGGCTGCGCAGGACGGCCAG
ATCGGACAGGTCGTCTACGGATCATGCAAGGCGGGCGTCAATGGCCTCGTTCTGCCAATGGCACGTGACCTGATGGACAT
CGGCATCCGCGTCAACTCGATCATGCCGGGCATTTTCGGCACGCCGCTGATGCTGCGCGCATCGGATAAGGTGCTCAACT
CCCTCGCCTCGTCGGTGCCCTTCCCCAAACGCCTCGGCAAACCGGAAGAGTTTGGCTCGCTGGTGATGGAACTGGTGCGC
AACACCTATTTCAACGGTCAGAACCTGCGTCTTGACGGCGGCATCCGGATGGCGCCGCGCTGA

Upstream 100 bases:

>100_bases
GCTTCATTTGAAGCGGGCGGCCTTGGCGCGGCGTCACCATTTCCAAGCCCGCCTTCCCTGCCTACACATGGGAAAAGTCA
GCTTTGGGAAGGAGACCTCC

Downstream 100 bases:

>100_bases
AGGATTTCCTGAAGCGACTTTAAGGCCTTTTGAAGCCCCGTGACCCTGACGGTTGCGGGGCTTTTTTGTTGTGGCGGTGC
TTTGCTGGGCGGAATAATAT

Product: short chain dehydrogenase/reductase family protein

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MQITKDTAAIVTGGASGLGQATARALAKAGAKVAIFDINEEAGEATAKEIGGIFCNVNIMDEASAVAGFEKARAAHGQER
ITVHCAMASKGGKTLSWDKENARYKRLTTEDYEFGAKGVLVASYRIASLSAEGMANLPELEDGERGVITLTASVAAQDGQ
IGQVVYGSCKAGVNGLVLPMARDLMDIGIRVNSIMPGIFGTPLMLRASDKVLNSLASSVPFPKRLGKPEEFGSLVMELVR
NTYFNGQNLRLDGGIRMAPR

Sequences:

>Translated_260_residues
MQITKDTAAIVTGGASGLGQATARALAKAGAKVAIFDINEEAGEATAKEIGGIFCNVNIMDEASAVAGFEKARAAHGQER
ITVHCAMASKGGKTLSWDKENARYKRLTTEDYEFGAKGVLVASYRIASLSAEGMANLPELEDGERGVITLTASVAAQDGQ
IGQVVYGSCKAGVNGLVLPMARDLMDIGIRVNSIMPGIFGTPLMLRASDKVLNSLASSVPFPKRLGKPEEFGSLVMELVR
NTYFNGQNLRLDGGIRMAPR
>Mature_260_residues
MQITKDTAAIVTGGASGLGQATARALAKAGAKVAIFDINEEAGEATAKEIGGIFCNVNIMDEASAVAGFEKARAAHGQER
ITVHCAMASKGGKTLSWDKENARYKRLTTEDYEFGAKGVLVASYRIASLSAEGMANLPELEDGERGVITLTASVAAQDGQ
IGQVVYGSCKAGVNGLVLPMARDLMDIGIRVNSIMPGIFGTPLMLRASDKVLNSLASSVPFPKRLGKPEEFGSLVMELVR
NTYFNGQNLRLDGGIRMAPR

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4758504, Length=258, Percent_Identity=41.0852713178295, Blast_Score=190, Evalue=1e-48,
Organism=Homo sapiens, GI83715985, Length=258, Percent_Identity=38.7596899224806, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI15277342, Length=264, Percent_Identity=26.8939393939394, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI40254992, Length=254, Percent_Identity=25.1968503937008, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=28.6259541984733, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=28.4584980237154, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=30.7392996108949, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=260, Percent_Identity=41.1538461538462, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=29.1338582677165, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25147288, Length=257, Percent_Identity=26.0700389105058, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17737361, Length=260, Percent_Identity=43.4615384615385, Blast_Score=196, Evalue=9e-51,
Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=29.6875, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27412; Mature: 27412

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQITKDTAAIVTGGASGLGQATARALAKAGAKVAIFDINEEAGEATAKEIGGIFCNVNIM
CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCHHCHHHHHHHCCEEEEEEEC
DEASAVAGFEKARAAHGQERITVHCAMASKGGKTLSWDKENARYKRLTTEDYEFGAKGVL
CCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEECCCCCEEEECCCCCCCCCCCEEE
VASYRIASLSAEGMANLPELEDGERGVITLTASVAAQDGQIGQVVYGSCKAGVNGLVLPM
EEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCEEEEECHHCCCCEEEHHH
ARDLMDIGIRVNSIMPGIFGTPLMLRASDKVLNSLASSVPFPKRLGKPEEFGSLVMELVR
HHHHHHHCEEEEHCCCCCCCCCEEEECHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHH
NTYFNGQNLRLDGGIRMAPR
HHCCCCCEEEECCCEEECCC
>Mature Secondary Structure
MQITKDTAAIVTGGASGLGQATARALAKAGAKVAIFDINEEAGEATAKEIGGIFCNVNIM
CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCHHCHHHHHHHCCEEEEEEEC
DEASAVAGFEKARAAHGQERITVHCAMASKGGKTLSWDKENARYKRLTTEDYEFGAKGVL
CCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEECCCCCEEEECCCCCCCCCCCEEE
VASYRIASLSAEGMANLPELEDGERGVITLTASVAAQDGQIGQVVYGSCKAGVNGLVLPM
EEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCEEEEECHHCCCCEEEHHH
ARDLMDIGIRVNSIMPGIFGTPLMLRASDKVLNSLASSVPFPKRLGKPEEFGSLVMELVR
HHHHHHHCEEEEHCCCCCCCCCEEEECHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHH
NTYFNGQNLRLDGGIRMAPR
HHCCCCCEEEECCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]