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The map label for this gene is glnL [C]

Identifier: 114800221

GI number: 114800221

Start: 2089476

End: 2090534

Strand: Reverse

Name: glnL [C]

Synonym: HNE_2012

Alternate gene names: 114800221

Gene position: 2090534-2089476 (Counterclockwise)

Preceding gene: 114799466

Following gene: 114799444

Centisome position: 56.42

GC content: 66.38

Gene sequence:

>1059_bases
ATGACGACTTTGACTGGCGAGCGGCCCTCCGGCCTCGCAGATCTGTCCCCCATCGCGCTGCTGCATGTTGATCAGCGCCG
CCGCATCGCGAATGTGAACCCGGCGGTTGAGGACATGTTCAAGCTCTCGCGCCGCGCGCTGGTCGGGCGCCCGCTGAGCG
AAGTGGTGTTTCACGACTCCATTCTCTTCGAGCTGATCGACCGGGCCGAGCGCGATCCGGCTGAGATCACCGCGCCCTCC
ACACCGGTGTCCGGCCCCTCCATGCAGGTCCGCACCATCTGCGACGTTCGCATCCGCACAGTCGAAGGGGGTAATTTCAT
CCTCGCCATGGCGGAGGCCCCGTCGCGGGATTCCGGCGAAGGCGTCGCCGGCGCAGCCGGGTTCGGGCGCATCCTCGGCC
ATGAAGTGAAAAACCCGCTCGCCGGCATCATCGGCGCCGCCCAGCTGCTCGAGCGCCAGGCCCATGCCGGTCAGAGCGAG
CTGCTCGACATTATCAAGGACGAAGCCCGCCGCATCGAGCGCCTCGTAAACCGCCTCTCGGCGTTCGAGCTGTTCTCCGC
GCCCCGCATGCAGGCCTGCAACGTCCACGCGCTGCTCGACAAGGTGATCGCTTCGGAACGCGCCGCGATGGGCGCGCGCG
TTGAGTTCCGCCGGGACTTTGACCCCTCCTTGCCAAACATGATGGGCGATCCCGATCACCTTCAGCAGGCCTTCCAGAAT
ATCGTCCGCAACGCCGCCGAAGCTGCCTCCGAAGGCGGACGCAAAGGCGAGGTCGTCCTGCGTACCGCCTATGCCGCCGG
CCTTGCCGTGCGACAGGCCCGGCTCGGGTCCGGCCTGCGCCGCGCGATGCTGATTTCCTTTGAAGACAACGGCCAGGGCA
TCCCGCGCGAGCATCAGGCCACGATCTTTGACGTGTTCCAGAGCACCAAATCCGGCGGCCGGGGCCTCGGCCTCTCGATC
GTCAGCGAAGTCGTCAATGCCCATGGCGGCCAGATCCGCGTCGACAGCCAGCCGGGCGCTACCCGTTTCACCATTCTGTT
GCCGCTTTCGGAGGCGTAA

Upstream 100 bases:

>100_bases
AGCTGCGCGCCGATCTCTGCCGGATAGGGGACGCCGGAGAGCTGATCGCTGCGCTGCGTAAGGTCTATCTTGGAAAGGTG
TTGGAGAAGGCGGTGTCCTC

Downstream 100 bases:

>100_bases
ATCTCATGGCCGACAAGACTGTTCTCCTCGCTGAAGACGATGCCAGCATCCGGCTCGTCGTGAACCAGACCCTGGTGTCC
GCAGGCTATGAGGTGCGCGC

Product: nitrogen regulation protein NR(II)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTTLTGERPSGLADLSPIALLHVDQRRRIANVNPAVEDMFKLSRRALVGRPLSEVVFHDSILFELIDRAERDPAEITAPS
TPVSGPSMQVRTICDVRIRTVEGGNFILAMAEAPSRDSGEGVAGAAGFGRILGHEVKNPLAGIIGAAQLLERQAHAGQSE
LLDIIKDEARRIERLVNRLSAFELFSAPRMQACNVHALLDKVIASERAAMGARVEFRRDFDPSLPNMMGDPDHLQQAFQN
IVRNAAEAASEGGRKGEVVLRTAYAAGLAVRQARLGSGLRRAMLISFEDNGQGIPREHQATIFDVFQSTKSGGRGLGLSI
VSEVVNAHGGQIRVDSQPGATRFTILLPLSEA

Sequences:

>Translated_352_residues
MTTLTGERPSGLADLSPIALLHVDQRRRIANVNPAVEDMFKLSRRALVGRPLSEVVFHDSILFELIDRAERDPAEITAPS
TPVSGPSMQVRTICDVRIRTVEGGNFILAMAEAPSRDSGEGVAGAAGFGRILGHEVKNPLAGIIGAAQLLERQAHAGQSE
LLDIIKDEARRIERLVNRLSAFELFSAPRMQACNVHALLDKVIASERAAMGARVEFRRDFDPSLPNMMGDPDHLQQAFQN
IVRNAAEAASEGGRKGEVVLRTAYAAGLAVRQARLGSGLRRAMLISFEDNGQGIPREHQATIFDVFQSTKSGGRGLGLSI
VSEVVNAHGGQIRVDSQPGATRFTILLPLSEA
>Mature_351_residues
TTLTGERPSGLADLSPIALLHVDQRRRIANVNPAVEDMFKLSRRALVGRPLSEVVFHDSILFELIDRAERDPAEITAPST
PVSGPSMQVRTICDVRIRTVEGGNFILAMAEAPSRDSGEGVAGAAGFGRILGHEVKNPLAGIIGAAQLLERQAHAGQSEL
LDIIKDEARRIERLVNRLSAFELFSAPRMQACNVHALLDKVIASERAAMGARVEFRRDFDPSLPNMMGDPDHLQQAFQNI
VRNAAEAASEGGRKGEVVLRTAYAAGLAVRQARLGSGLRRAMLISFEDNGQGIPREHQATIFDVFQSTKSGGRGLGLSIV
SEVVNAHGGQIRVDSQPGATRFTILLPLSEA

Specific function: NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC. In nitrogen limitation ntrB activates ntrC by phosphorylating it, while in nitrogen excess ntrC is dephosphorylated and consequently inactiva

COG id: COG3852

COG function: function code T; Signal transduction histidine kinase, nitrogen specific

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790300, Length=358, Percent_Identity=33.5195530726257, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788549, Length=348, Percent_Identity=29.0229885057471, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=30.9417040358744, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=29.004329004329, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786600, Length=235, Percent_Identity=27.2340425531915, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789149, Length=221, Percent_Identity=27.1493212669683, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=27.4193548387097, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87081816, Length=271, Percent_Identity=29.520295202952, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 37961; Mature: 37830

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLTGERPSGLADLSPIALLHVDQRRRIANVNPAVEDMFKLSRRALVGRPLSEVVFHDS
CCCCCCCCCCCCCCCCCCCEEEEHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
ILFELIDRAERDPAEITAPSTPVSGPSMQVRTICDVRIRTVEGGNFILAMAEAPSRDSGE
HHHHHHHHHCCCCCCEECCCCCCCCCCCEEEEEEEEEEEEEECCCEEEEEECCCCCCCCC
GVAGAAGFGRILGHEVKNPLAGIIGAAQLLERQAHAGQSELLDIIKDEARRIERLVNRLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AFELFSAPRMQACNVHALLDKVIASERAAMGARVEFRRDFDPSLPNMMGDPDHLQQAFQN
HHHHHCCCCCHHCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHHHHHH
IVRNAAEAASEGGRKGEVVLRTAYAAGLAVRQARLGSGLRRAMLISFEDNGQGIPREHQA
HHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHH
TIFDVFQSTKSGGRGLGLSIVSEVVNAHGGQIRVDSQPGATRFTILLPLSEA
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEECCCC
>Mature Secondary Structure 
TTLTGERPSGLADLSPIALLHVDQRRRIANVNPAVEDMFKLSRRALVGRPLSEVVFHDS
CCCCCCCCCCCCCCCCCCEEEEHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
ILFELIDRAERDPAEITAPSTPVSGPSMQVRTICDVRIRTVEGGNFILAMAEAPSRDSGE
HHHHHHHHHCCCCCCEECCCCCCCCCCCEEEEEEEEEEEEEECCCEEEEEECCCCCCCCC
GVAGAAGFGRILGHEVKNPLAGIIGAAQLLERQAHAGQSELLDIIKDEARRIERLVNRLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AFELFSAPRMQACNVHALLDKVIASERAAMGARVEFRRDFDPSLPNMMGDPDHLQQAFQN
HHHHHCCCCCHHCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHHHHHH
IVRNAAEAASEGGRKGEVVLRTAYAAGLAVRQARLGSGLRRAMLISFEDNGQGIPREHQA
HHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHH
TIFDVFQSTKSGGRGLGLSIVSEVVNAHGGQIRVDSQPGATRFTILLPLSEA
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7553451 [H]