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The map label for this gene is aroK [H]

Identifier: 114800012

GI number: 114800012

Start: 65507

End: 66067

Strand: Direct

Name: aroK [H]

Synonym: HNE_0081

Alternate gene names: 114800012

Gene position: 65507-66067 (Clockwise)

Preceding gene: 114797180

Following gene: 114797725

Centisome position: 1.77

GC content: 62.03

Gene sequence:

>561_bases
ATGCCTTCCGATACCGACCCATCAAGTAGCCCGCTGCCCTTCGAGGGCCGCACGATCGCGCTTGTGGGGCTCATGGGCGC
CGGAAAATCGACCGTCGGGCGGCGCCTTGCCGAAAAACTCGGCCGTGATTTTTATGACAGCGACCATGAAATCGAGAAGG
CGGCCGGGCTCTCGATCTCCGATATTTTTGCCAAACATGGCGAAGCCGATTTCCGGCGCGGTGAAAAGCAGGTGATCCGC
CGCCTGCTGGACCTGCAACCGCATGTGCTGGCGACCGGGGGCGGGGCCTATCTCGATCCCGATACGCGCGCCATTTTGCG
GGAGCGGGCCATCACGGTCTGGCTCAACGCTGACCTCGAAACATTGTGGCGCCGTGTCCAGAAGCGCGATACGCGCCCGC
TGCTTCAGCGCGCTGACGCCCGCGACCACCTTGCCAATCTCGCGCTGGACCGTGAGCCCTTCTATTCGCAGGCCGACCTT
GTGGTTCATTCCAAGGATGGCCCGCACACCCACACCGTCAATGCGATCCTGAAAGCCCTTCAGACCTGGATACCTCAATG
A

Upstream 100 bases:

>100_bases
AGGCCCCGCAAGCAAGTATGACAGGGCGAATCTGCCTGCCGATTGCGCCGCCTATGTGGCACCCCTAGGACATATTCGCA
ACGCCGGGTAATACGAACAC

Downstream 100 bases:

>100_bases
AAACTTCTTCCCCGCTGGAAACGGTGCGCGTTGAACTGGGCGCGCGAGCGTACGACATTCTCGTGGGCCATGGCGCGCTC
TCAGAACTCGGCCCGCGTCT

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MPSDTDPSSSPLPFEGRTIALVGLMGAGKSTVGRRLAEKLGRDFYDSDHEIEKAAGLSISDIFAKHGEADFRRGEKQVIR
RLLDLQPHVLATGGGAYLDPDTRAILRERAITVWLNADLETLWRRVQKRDTRPLLQRADARDHLANLALDREPFYSQADL
VVHSKDGPHTHTVNAILKALQTWIPQ

Sequences:

>Translated_186_residues
MPSDTDPSSSPLPFEGRTIALVGLMGAGKSTVGRRLAEKLGRDFYDSDHEIEKAAGLSISDIFAKHGEADFRRGEKQVIR
RLLDLQPHVLATGGGAYLDPDTRAILRERAITVWLNADLETLWRRVQKRDTRPLLQRADARDHLANLALDREPFYSQADL
VVHSKDGPHTHTVNAILKALQTWIPQ
>Mature_185_residues
PSDTDPSSSPLPFEGRTIALVGLMGAGKSTVGRRLAEKLGRDFYDSDHEIEKAAGLSISDIFAKHGEADFRRGEKQVIRR
LLDLQPHVLATGGGAYLDPDTRAILRERAITVWLNADLETLWRRVQKRDTRPLLQRADARDHLANLALDREPFYSQADLV
VHSKDGPHTHTVNAILKALQTWIPQ

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=170, Percent_Identity=41.7647058823529, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1786587, Length=164, Percent_Identity=28.0487804878049, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 20779; Mature: 20648

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSDTDPSSSPLPFEGRTIALVGLMGAGKSTVGRRLAEKLGRDFYDSDHEIEKAAGLSIS
CCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCHHHCCCCHHHHHHHCCCHH
DIFAKHGEADFRRGEKQVIRRLLDLQPHVLATGGGAYLDPDTRAILRERAITVWLNADLE
HHHHHCCCHHHHCCHHHHHHHHHCCCCCEEEECCCCEECCHHHHHHHHHHEEEEECCCHH
TLWRRVQKRDTRPLLQRADARDHLANLALDREPFYSQADLVVHSKDGPHTHTVNAILKAL
HHHHHHHHCCCHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHH
QTWIPQ
HHHCCC
>Mature Secondary Structure 
PSDTDPSSSPLPFEGRTIALVGLMGAGKSTVGRRLAEKLGRDFYDSDHEIEKAAGLSIS
CCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCHHHCCCCHHHHHHHCCCHH
DIFAKHGEADFRRGEKQVIRRLLDLQPHVLATGGGAYLDPDTRAILRERAITVWLNADLE
HHHHHCCCHHHHCCHHHHHHHHHCCCCCEEEECCCCEECCHHHHHHHHHHEEEEECCCHH
TLWRRVQKRDTRPLLQRADARDHLANLALDREPFYSQADLVVHSKDGPHTHTVNAILKAL
HHHHHHHHCCCHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHH
QTWIPQ
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA