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The map label for this gene is aroB

Identifier: 114797725

GI number: 114797725

Start: 66064

End: 67185

Strand: Direct

Name: aroB

Synonym: HNE_0082

Alternate gene names: 114797725

Gene position: 66064-67185 (Clockwise)

Preceding gene: 114800012

Following gene: 114798726

Centisome position: 1.78

GC content: 64.17

Gene sequence:

>1122_bases
ATGAAAACTTCTTCCCCGCTGGAAACGGTGCGCGTTGAACTGGGCGCGCGAGCGTACGACATTCTCGTGGGCCATGGCGC
GCTCTCAGAACTCGGCCCGCGTCTCTCGCAGATGCTCAAGCGGCCACGCGCCTTTGTTCTGACCGATGAAACGGTGGCGC
GCCATCACAAGGACGCGCTGGAAGCGGCGGTTAAATCCGCTGGCATCCGGCTGGACTGGTTGAGCCTGCCGCCGGGCGAG
AAGACCAAGTCCTTTTCCCAGCTGGAGGGTGTGCTGGACTGGCTGCTGGCGGGCGGCGCAGACCGGGGCGATACGCTGAT
CGCGTTTGGTGGCGGGGTCATCGGCGATATGGGCGGCCTTGCCGCCAGCCTGATGAAGCGCGGCATGGGATTTGTGCAGG
TGCCGACCACGCTTCTGGCGCAGGTCGATTCTTCGGTTGGCGGAAAAACGGCGGTCAATACGCCGCGCGGCAAAAACCTG
ATCGGCGCCTTCTACCAGCCGCGCCTGGTGATTGCCGATACCGCGCTTCTCGCGACGCTTCCGGCGCGGGAGCTCAAAGC
GGGCTATGCCGAGATTGTCAAATATGGCCTGATCAACGATGCCGCCTTCTTTGACTGGCTGGCCGTGAACGGACAGAAAG
TTCTGGCGCTTGAGCCTGAAGCCGCCCGTTACGCCGTGGCGCGGTCCTGTGCTGCCAAGGCGGCGATTGTGGCGGAAGAT
GAAACCGAGACCGGCGTGCGCCAGCTGCTCAATCTTGGCCATACATTCGGGCATGCTTTCGAGGCGGCCAACGAATACCG
GGAGAACCTCCTTCATGGCGAGGCCGTTGCGCTGGGCATGGCATTGGCGTTTCGTTATGGCGCCGCCAGCGGCATCACGC
CGGCGGCAGACGCGGCGCGGGTTACCGAAGTGCTGGGCGCGTCGGGCCTTCCGGTATCGCTCGAAGGTTTTGACCCCGCC
CGCTTCGCCGCAGACCGTCTTGCCGCCCTGATGCAGCAGGACAAGAAGGCCCGTGCGGGCCGCGTTCCGCTGATCCTCGC
CCGCGGAATCGGCGCGGCTTACGTCCATCCCGATGCGGACCTTGCTTCGGTCGAACGCTTTCTCGCATCTGAACTTGCCT
AA

Upstream 100 bases:

>100_bases
CCTTCTATTCGCAGGCCGACCTTGTGGTTCATTCCAAGGATGGCCCGCACACCCACACCGTCAATGCGATCCTGAAAGCC
CTTCAGACCTGGATACCTCA

Downstream 100 bases:

>100_bases
CTCATTTTACAGAAACTGAGCCCACATAATGATCGCCGGATATGCCATCGCAATTGTCATCCTTCTGATGATGTCTGCCT
TCTTCTCAGGCTCTGAAACA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKTSSPLETVRVELGARAYDILVGHGALSELGPRLSQMLKRPRAFVLTDETVARHHKDALEAAVKSAGIRLDWLSLPPGE
KTKSFSQLEGVLDWLLAGGADRGDTLIAFGGGVIGDMGGLAASLMKRGMGFVQVPTTLLAQVDSSVGGKTAVNTPRGKNL
IGAFYQPRLVIADTALLATLPARELKAGYAEIVKYGLINDAAFFDWLAVNGQKVLALEPEAARYAVARSCAAKAAIVAED
ETETGVRQLLNLGHTFGHAFEAANEYRENLLHGEAVALGMALAFRYGAASGITPAADAARVTEVLGASGLPVSLEGFDPA
RFAADRLAALMQQDKKARAGRVPLILARGIGAAYVHPDADLASVERFLASELA

Sequences:

>Translated_373_residues
MKTSSPLETVRVELGARAYDILVGHGALSELGPRLSQMLKRPRAFVLTDETVARHHKDALEAAVKSAGIRLDWLSLPPGE
KTKSFSQLEGVLDWLLAGGADRGDTLIAFGGGVIGDMGGLAASLMKRGMGFVQVPTTLLAQVDSSVGGKTAVNTPRGKNL
IGAFYQPRLVIADTALLATLPARELKAGYAEIVKYGLINDAAFFDWLAVNGQKVLALEPEAARYAVARSCAAKAAIVAED
ETETGVRQLLNLGHTFGHAFEAANEYRENLLHGEAVALGMALAFRYGAASGITPAADAARVTEVLGASGLPVSLEGFDPA
RFAADRLAALMQQDKKARAGRVPLILARGIGAAYVHPDADLASVERFLASELA
>Mature_373_residues
MKTSSPLETVRVELGARAYDILVGHGALSELGPRLSQMLKRPRAFVLTDETVARHHKDALEAAVKSAGIRLDWLSLPPGE
KTKSFSQLEGVLDWLLAGGADRGDTLIAFGGGVIGDMGGLAASLMKRGMGFVQVPTTLLAQVDSSVGGKTAVNTPRGKNL
IGAFYQPRLVIADTALLATLPARELKAGYAEIVKYGLINDAAFFDWLAVNGQKVLALEPEAARYAVARSCAAKAAIVAED
ETETGVRQLLNLGHTFGHAFEAANEYRENLLHGEAVALGMALAFRYGAASGITPAADAARVTEVLGASGLPVSLEGFDPA
RFAADRLAALMQQDKKARAGRVPLILARGIGAAYVHPDADLASVERFLASELA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=349, Percent_Identity=46.4183381088825, Blast_Score=272, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6320332, Length=320, Percent_Identity=37.8125, Blast_Score=183, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_HYPNA (Q0C627)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_758816.1
- ProteinModelPortal:   Q0C627
- SMR:   Q0C627
- STRING:   Q0C627
- GeneID:   4289240
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_0082
- NMPDR:   fig|228405.5.peg.81
- TIGR:   HNE_0082
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   GWIDESI
- PhylomeDB:   Q0C627
- ProtClustDB:   PRK00002
- BioCyc:   HNEP81032:HNE_0082-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 39267; Mature: 39267

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSSPLETVRVELGARAYDILVGHGALSELGPRLSQMLKRPRAFVLTDETVARHHKDAL
CCCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHH
EAAVKSAGIRLDWLSLPPGEKTKSFSQLEGVLDWLLAGGADRGDTLIAFGGGVIGDMGGL
HHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHH
AASLMKRGMGFVQVPTTLLAQVDSSVGGKTAVNTPRGKNLIGAFYQPRLVIADTALLATL
HHHHHHCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCEEEEEHHHHHHHC
PARELKAGYAEIVKYGLINDAAFFDWLAVNGQKVLALEPEAARYAVARSCAAKAAIVAED
CHHHHHHHHHHHHHHHCCCCHHHHHHHEECCCEEEEECCHHHHHHHHHHHHHHHEEEECC
ETETGVRQLLNLGHTFGHAFEAANEYRENLLHGEAVALGMALAFRYGAASGITPAADAAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
VTEVLGASGLPVSLEGFDPARFAADRLAALMQQDKKARAGRVPLILARGIGAAYVHPDAD
HHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCCCC
LASVERFLASELA
HHHHHHHHHHHCC
>Mature Secondary Structure
MKTSSPLETVRVELGARAYDILVGHGALSELGPRLSQMLKRPRAFVLTDETVARHHKDAL
CCCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHH
EAAVKSAGIRLDWLSLPPGEKTKSFSQLEGVLDWLLAGGADRGDTLIAFGGGVIGDMGGL
HHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHH
AASLMKRGMGFVQVPTTLLAQVDSSVGGKTAVNTPRGKNLIGAFYQPRLVIADTALLATL
HHHHHHCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCEEEEEHHHHHHHC
PARELKAGYAEIVKYGLINDAAFFDWLAVNGQKVLALEPEAARYAVARSCAAKAAIVAED
CHHHHHHHHHHHHHHHCCCCHHHHHHHEECCCEEEEECCHHHHHHHHHHHHHHHEEEECC
ETETGVRQLLNLGHTFGHAFEAANEYRENLLHGEAVALGMALAFRYGAASGITPAADAAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
VTEVLGASGLPVSLEGFDPARFAADRLAALMQQDKKARAGRVPLILARGIGAAYVHPDAD
HHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCCCC
LASVERFLASELA
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA