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The map label for this gene is 114799874

Identifier: 114799874

GI number: 114799874

Start: 2136749

End: 2137540

Strand: Reverse

Name: 114799874

Synonym: HNE_2063

Alternate gene names: NA

Gene position: 2137540-2136749 (Counterclockwise)

Preceding gene: 114799236

Following gene: 114797766

Centisome position: 57.69

GC content: 61.99

Gene sequence:

>792_bases
ATGGCCGACGGCGCAGGTAAAATCGACATCCGCAATTCTGTCAGCGAAGCCGAATGGCAGGCGCGCGTAGATCTCGCGGC
GATGTACCGTCTCACCGCGCTTTACGGCTGGGATGATATGATCTTCACGCACATCTCCCACCGCGTCCCCGGCCCGGAAC
ACCACTTCCTGATCAATCCCTACGGCTATTTCTTCGAGGAAATCACCGCCTCCTCGCTGGTGAAGGTCGATCTGGACGGC
AACATCGTTCAGGAAACCGATGCGATGATCAATCCAGCCGGCTTCACCATCCACTCGGCCATCCATGCCGCGCGCGACGA
CGCCCATGTCGTCATGCACGTTCACACCGATCAGGGCGTGGCGGTCTCCGCCCAGAAAGAAGGTCTCCTCCCGCTCAGCC
AGACGGCCATGATCGTGCGCGAAGATGTCGCTTACCATGATTACGAGGGCATCGCCCTTGATCTGGACGAACGCGAGCGC
CTGGTGCGCGACCTTGGCGAGAAGAAGCATTCGATGATCCTGCGCAACCACGGCACGCTCACCTGCGGCGCCACGGCGGC
CATCACCTTCAGCCGCATGTTCTTCCTGGAGCGGGCCTGCACCATGCAGATCATGGCGCTTTCGGCAGGCCGCGACGGTG
TTCTGGAGTGCGATACCGGCCTTCAGCAGAAGGTCGCCGGGCAGGGTGGGATGACCGAGCACAGCAACGGCATGGCTAAG
CTGACCGACATGCTCGTCTGGCCCGCGCTCCTGCGCAAGCTCGACCGGGATCTGCCCGGTTATGCCGCATAG

Upstream 100 bases:

>100_bases
GCGCGTCATCTGAATCTGGCGCTGACGGCCAAACTCGTTTACTTTCGCCTGCGAAACCGCAGATCACGCCCAGAGAAACG
CATTGAGGGAGACTATCACC

Downstream 100 bases:

>100_bases
GTATTTTCCCTGATTAGACTAAATGGGTTGCCGGAATAAGCCTCCGGTAACCCAAGTTAAACATGGTCATAGTCGAAAAG
AGTTCAGAGTAGCGCCATGC

Product: aldolase II superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MADGAGKIDIRNSVSEAEWQARVDLAAMYRLTALYGWDDMIFTHISHRVPGPEHHFLINPYGYFFEEITASSLVKVDLDG
NIVQETDAMINPAGFTIHSAIHAARDDAHVVMHVHTDQGVAVSAQKEGLLPLSQTAMIVREDVAYHDYEGIALDLDERER
LVRDLGEKKHSMILRNHGTLTCGATAAITFSRMFFLERACTMQIMALSAGRDGVLECDTGLQQKVAGQGGMTEHSNGMAK
LTDMLVWPALLRKLDRDLPGYAA

Sequences:

>Translated_263_residues
MADGAGKIDIRNSVSEAEWQARVDLAAMYRLTALYGWDDMIFTHISHRVPGPEHHFLINPYGYFFEEITASSLVKVDLDG
NIVQETDAMINPAGFTIHSAIHAARDDAHVVMHVHTDQGVAVSAQKEGLLPLSQTAMIVREDVAYHDYEGIALDLDERER
LVRDLGEKKHSMILRNHGTLTCGATAAITFSRMFFLERACTMQIMALSAGRDGVLECDTGLQQKVAGQGGMTEHSNGMAK
LTDMLVWPALLRKLDRDLPGYAA
>Mature_262_residues
ADGAGKIDIRNSVSEAEWQARVDLAAMYRLTALYGWDDMIFTHISHRVPGPEHHFLINPYGYFFEEITASSLVKVDLDGN
IVQETDAMINPAGFTIHSAIHAARDDAHVVMHVHTDQGVAVSAQKEGLLPLSQTAMIVREDVAYHDYEGIALDLDERERL
VRDLGEKKHSMILRNHGTLTCGATAAITFSRMFFLERACTMQIMALSAGRDGVLECDTGLQQKVAGQGGMTEHSNGMAKL
TDMLVWPALLRKLDRDLPGYAA

Specific function: Unknown

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family [H]

Homologues:

Organism=Homo sapiens, GI29826325, Length=209, Percent_Identity=46.88995215311, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI29826323, Length=209, Percent_Identity=46.88995215311, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI29826321, Length=209, Percent_Identity=46.88995215311, Blast_Score=178, Evalue=3e-45,
Organism=Homo sapiens, GI29826319, Length=209, Percent_Identity=46.88995215311, Blast_Score=178, Evalue=4e-45,
Organism=Homo sapiens, GI297307160, Length=200, Percent_Identity=39, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI89276787, Length=200, Percent_Identity=39, Blast_Score=148, Evalue=4e-36,
Organism=Homo sapiens, GI9257190, Length=200, Percent_Identity=39, Blast_Score=148, Evalue=4e-36,
Organism=Homo sapiens, GI297307158, Length=191, Percent_Identity=40.3141361256544, Blast_Score=148, Evalue=5e-36,
Organism=Homo sapiens, GI9257192, Length=191, Percent_Identity=40.3141361256544, Blast_Score=148, Evalue=5e-36,
Organism=Homo sapiens, GI9951927, Length=205, Percent_Identity=40, Blast_Score=147, Evalue=9e-36,
Organism=Homo sapiens, GI62912453, Length=205, Percent_Identity=40, Blast_Score=147, Evalue=9e-36,
Organism=Homo sapiens, GI9943848, Length=205, Percent_Identity=40, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI115533216, Length=249, Percent_Identity=43.3734939759036, Blast_Score=181, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI115533218, Length=249, Percent_Identity=43.3734939759036, Blast_Score=180, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI71989550, Length=207, Percent_Identity=36.231884057971, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71989555, Length=207, Percent_Identity=36.231884057971, Blast_Score=121, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71989544, Length=207, Percent_Identity=36.231884057971, Blast_Score=121, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71989541, Length=207, Percent_Identity=36.231884057971, Blast_Score=121, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71989560, Length=207, Percent_Identity=36.231884057971, Blast_Score=121, Evalue=4e-28,
Organism=Drosophila melanogaster, GI281363755, Length=196, Percent_Identity=39.7959183673469, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI281363751, Length=196, Percent_Identity=39.7959183673469, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24655690, Length=196, Percent_Identity=39.7959183673469, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24655685, Length=196, Percent_Identity=39.7959183673469, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI281363761, Length=196, Percent_Identity=39.7959183673469, Blast_Score=144, Evalue=7e-35,
Organism=Drosophila melanogaster, GI281363759, Length=196, Percent_Identity=39.7959183673469, Blast_Score=144, Evalue=7e-35,
Organism=Drosophila melanogaster, GI281363753, Length=196, Percent_Identity=39.7959183673469, Blast_Score=144, Evalue=7e-35,
Organism=Drosophila melanogaster, GI281363763, Length=196, Percent_Identity=39.7959183673469, Blast_Score=143, Evalue=9e-35,
Organism=Drosophila melanogaster, GI281363757, Length=196, Percent_Identity=39.7959183673469, Blast_Score=143, Evalue=9e-35,
Organism=Drosophila melanogaster, GI17136738, Length=196, Percent_Identity=39.7959183673469, Blast_Score=143, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: NA

Molecular weight: Translated: 29037; Mature: 28906

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADGAGKIDIRNSVSEAEWQARVDLAAMYRLTALYGWDDMIFTHISHRVPGPEHHFLINP
CCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEECH
YGYFFEEITASSLVKVDLDGNIVQETDAMINPAGFTIHSAIHAARDDAHVVMHVHTDQGV
HHHHHHHHHHCCEEEEECCCCEEECHHCEECCCCHHHHHHHHHCCCCCEEEEEEECCCCE
AVSAQKEGLLPLSQTAMIVREDVAYHDYEGIALDLDERERLVRDLGEKKHSMILRNHGTL
EEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHEEEECCCCE
TCGATAAITFSRMFFLERACTMQIMALSAGRDGVLECDTGLQQKVAGQGGMTEHSNGMAK
EECCHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEECCCCHHHHHCCCCCCCCCCCCHHH
LTDMLVWPALLRKLDRDLPGYAA
HHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ADGAGKIDIRNSVSEAEWQARVDLAAMYRLTALYGWDDMIFTHISHRVPGPEHHFLINP
CCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEECH
YGYFFEEITASSLVKVDLDGNIVQETDAMINPAGFTIHSAIHAARDDAHVVMHVHTDQGV
HHHHHHHHHHCCEEEEECCCCEEECHHCEECCCCHHHHHHHHHCCCCCEEEEEEECCCCE
AVSAQKEGLLPLSQTAMIVREDVAYHDYEGIALDLDERERLVRDLGEKKHSMILRNHGTL
EEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHEEEECCCCE
TCGATAAITFSRMFFLERACTMQIMALSAGRDGVLECDTGLQQKVAGQGGMTEHSNGMAK
EECCHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEECCCCHHHHHCCCCCCCCCCCCHHH
LTDMLVWPALLRKLDRDLPGYAA
HHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]