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The map label for this gene is surE

Identifier: 114799382

GI number: 114799382

Start: 1998979

End: 1999740

Strand: Reverse

Name: surE

Synonym: HNE_1929

Alternate gene names: 114799382

Gene position: 1999740-1998979 (Counterclockwise)

Preceding gene: 114800440

Following gene: 114800134

Centisome position: 53.97

GC content: 62.47

Gene sequence:

>762_bases
ATGAGAATTCTCCTGACCAATGATGACGGCATCAACGCCCCCGGCCTCTCCGTGCTGGAGGAGATTGCCAAGGAAATTTC
TGACGACATCTGGATTGCCGCGCCTGAAGAGGAACAGTCCGGCAAGGGCCGCGCGATTTCGCTGACCCATCCGGTGCGGG
TGCGCAAGGTGGGCGCGAAGGCGTGGGCCGTTTCGGGCACGCCGTCGGACGCGGTGCTGCTGGCCACGCGCGACCTGATG
CCGGATATGCCCGACCTGGTGCTGTCGGGCGTCAATCGCGGCCAGAATATTGCCGAGGATACGAGCTTTTCCGGCACCAT
CGCGGCGGCCATGTTCGGCATGCAGCTGGGCGTGCCCTCCATCGCGCTCAGCCAGGCGCAGAATTTCCGCGAGCGCGGGT
CGCTGTCCTGGGAGACCTCGAAAGCCTGGGGCGCCAAGGCGATCCGGCCGCTGCTGGAGATGCGCTGGCCCAAAGACGTT
GTGATGAACGTCAACTTTCCGGATGTGGAGCCCGGCGATGTACGCGGTATTCAGATCACCCGGCAGGGTTTCCGCGATGA
GGCGATTATCCACACCGACCGGCGCGAAGACCTGCGCGGAAACGATTATTACTGGATCGGCTATCGCGGGAAGCTGTCCA
AGCCCGACGAAGGCACTGACATCCGGGCAATCTATGACGGCTACGTCTCGATCTCCCCGCTGCATGTGGACTTGACGCAT
GAGCCGTTCCTGAAAACGCTGAAGGAGTCATGGCAGAGCTGA

Upstream 100 bases:

>100_bases
ATCGATCACTGTGCCCAAGGCGCTGGTGCCCTATATGGGCGGGGTTGAGGTTATAAACTAAGTCCCTTCTTCCTTGGGGA
GGGGGAACGAAAGGACGGAT

Downstream 100 bases:

>100_bases
TCGCTGATCCCTTCCGCGCCGCGCGGCTGCTGCTCTCGCTGAGGCAGGAGGGGGTGACTGATCCCAGCGTTCTGGCGGCC
ATGGAAACGATCGGCCGGGC

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MRILLTNDDGINAPGLSVLEEIAKEISDDIWIAAPEEEQSGKGRAISLTHPVRVRKVGAKAWAVSGTPSDAVLLATRDLM
PDMPDLVLSGVNRGQNIAEDTSFSGTIAAAMFGMQLGVPSIALSQAQNFRERGSLSWETSKAWGAKAIRPLLEMRWPKDV
VMNVNFPDVEPGDVRGIQITRQGFRDEAIIHTDRREDLRGNDYYWIGYRGKLSKPDEGTDIRAIYDGYVSISPLHVDLTH
EPFLKTLKESWQS

Sequences:

>Translated_253_residues
MRILLTNDDGINAPGLSVLEEIAKEISDDIWIAAPEEEQSGKGRAISLTHPVRVRKVGAKAWAVSGTPSDAVLLATRDLM
PDMPDLVLSGVNRGQNIAEDTSFSGTIAAAMFGMQLGVPSIALSQAQNFRERGSLSWETSKAWGAKAIRPLLEMRWPKDV
VMNVNFPDVEPGDVRGIQITRQGFRDEAIIHTDRREDLRGNDYYWIGYRGKLSKPDEGTDIRAIYDGYVSISPLHVDLTH
EPFLKTLKESWQS
>Mature_253_residues
MRILLTNDDGINAPGLSVLEEIAKEISDDIWIAAPEEEQSGKGRAISLTHPVRVRKVGAKAWAVSGTPSDAVLLATRDLM
PDMPDLVLSGVNRGQNIAEDTSFSGTIAAAMFGMQLGVPSIALSQAQNFRERGSLSWETSKAWGAKAIRPLLEMRWPKDV
VMNVNFPDVEPGDVRGIQITRQGFRDEAIIHTDRREDLRGNDYYWIGYRGKLSKPDEGTDIRAIYDGYVSISPLHVDLTH
EPFLKTLKESWQS

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=240, Percent_Identity=39.1666666666667, Blast_Score=164, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_HYPNA (Q0C0W3)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_760630.1
- ProteinModelPortal:   Q0C0W3
- SMR:   Q0C0W3
- STRING:   Q0C0W3
- GeneID:   4288504
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_1929
- NMPDR:   fig|228405.5.peg.1857
- TIGR:   HNE_1929
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   ISYTHPM
- PhylomeDB:   Q0C0W3
- ProtClustDB:   PRK00346
- BioCyc:   HNEP81032:HNE_1929-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 28045; Mature: 28045

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLTNDDGINAPGLSVLEEIAKEISDDIWIAAPEEEQSGKGRAISLTHPVRVRKVGAK
CEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEECCEEEEEECCE
AWAVSGTPSDAVLLATRDLMPDMPDLVLSGVNRGQNIAEDTSFSGTIAAAMFGMQLGVPS
EEEECCCCCCEEEEEEHHCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCH
IALSQAQNFRERGSLSWETSKAWGAKAIRPLLEMRWPKDVVMNVNFPDVEPGDVRGIQIT
HHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEEE
RQGFRDEAIIHTDRREDLRGNDYYWIGYRGKLSKPDEGTDIRAIYDGYVSISPLHVDLTH
CCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCEEEEEEEEEECCC
EPFLKTLKESWQS
HHHHHHHHHHHCC
>Mature Secondary Structure
MRILLTNDDGINAPGLSVLEEIAKEISDDIWIAAPEEEQSGKGRAISLTHPVRVRKVGAK
CEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEECCEEEEEECCE
AWAVSGTPSDAVLLATRDLMPDMPDLVLSGVNRGQNIAEDTSFSGTIAAAMFGMQLGVPS
EEEECCCCCCEEEEEEHHCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCH
IALSQAQNFRERGSLSWETSKAWGAKAIRPLLEMRWPKDVVMNVNFPDVEPGDVRGIQIT
HHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEEE
RQGFRDEAIIHTDRREDLRGNDYYWIGYRGKLSKPDEGTDIRAIYDGYVSISPLHVDLTH
CCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCEEEEEEEEEECCC
EPFLKTLKESWQS
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA