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The map label for this gene is coaX

Identifier: 114799332

GI number: 114799332

Start: 1802037

End: 1802804

Strand: Direct

Name: coaX

Synonym: HNE_1760

Alternate gene names: 114799332

Gene position: 1802037-1802804 (Clockwise)

Preceding gene: 114798329

Following gene: 114800376

Centisome position: 48.64

GC content: 54.04

Gene sequence:

>768_bases
ATGCTTCTGGTTATCGACGTTGGGAACACCAATACTGTTTTTGCGCTCCATGATGGTGAGCAGTGGGTCAATCAGTGGCG
CAGCGCCACGGATTCAACAAAAACGGCGGATGACCATGCCTCGTGGCTTTGGCGGCTGGCTGATATGCAAGGCGTTGATC
TGTCTCGGGTTCAAGGATGCGTTGTTTCATCCGTTGTGCCGCACGCTCAGTTCAACTTTCGCAATTTGGCGCGGCGCTAT
TTGAACGTCGAGCCCTTGTTCATCGGGGAGCCGGGATTGAAAACCGGCATGGCGGTCAGAGTGCGTCACCCCGAACAGGT
CGGTGCCGACAGGATCGTTAGCGCCTTGGGCGCTCATGTAGCGTATCCCGGTGATCTGATCGTAATCGATAGCGGTACAG
CAACGACGTTTGATATTGTTTCAGCGGATGGTGCGTTTGAAGGTGGCATCATATCCCCAGGCATCTATCTCTCTATGAGA
GCCTTGCATGATGCCGCCGCGCAATTGCCGCGGATTGCGATTCAGAAGCCGCCGCAGGTCATAGGTAAAGACACTGTGTC
TGCCATGCAGTCAGGTGTGTTTATAGGGTATATTGAACTGATTGATGGTCTCGTTCGGCGCATCAAAGCCGAATGGGGGC
GTCCGATGACCGTGATTGCAACAGGGGGCGTGGCGTCTCTCTTCGAAGGAGCAAGCGAAACCATCGATTACTACGATCAA
GACATTCTTATCCGGGGGCTATTGGAAGTCTGGAAGCGGAACCGTTGA

Upstream 100 bases:

>100_bases
GGATCTCGAACAGGATGGTGCCCTTCGTCTTCGGTTGCCGGATGGAAGCGCGCGCATCATAAGGGCCGGCGAAGTAAACC
TTATTGGACGAGCGTAACGC

Downstream 100 bases:

>100_bases
CACTGAAGGAGACCACAATCGATCAGTCCAAGGACGAGCTCGTATTTCTTCCCCTCGGCGGTTGCGGCGAGATCGGAATG
AACCTCAATGCCTATGGATA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MLLVIDVGNTNTVFALHDGEQWVNQWRSATDSTKTADDHASWLWRLADMQGVDLSRVQGCVVSSVVPHAQFNFRNLARRY
LNVEPLFIGEPGLKTGMAVRVRHPEQVGADRIVSALGAHVAYPGDLIVIDSGTATTFDIVSADGAFEGGIISPGIYLSMR
ALHDAAAQLPRIAIQKPPQVIGKDTVSAMQSGVFIGYIELIDGLVRRIKAEWGRPMTVIATGGVASLFEGASETIDYYDQ
DILIRGLLEVWKRNR

Sequences:

>Translated_255_residues
MLLVIDVGNTNTVFALHDGEQWVNQWRSATDSTKTADDHASWLWRLADMQGVDLSRVQGCVVSSVVPHAQFNFRNLARRY
LNVEPLFIGEPGLKTGMAVRVRHPEQVGADRIVSALGAHVAYPGDLIVIDSGTATTFDIVSADGAFEGGIISPGIYLSMR
ALHDAAAQLPRIAIQKPPQVIGKDTVSAMQSGVFIGYIELIDGLVRRIKAEWGRPMTVIATGGVASLFEGASETIDYYDQ
DILIRGLLEVWKRNR
>Mature_255_residues
MLLVIDVGNTNTVFALHDGEQWVNQWRSATDSTKTADDHASWLWRLADMQGVDLSRVQGCVVSSVVPHAQFNFRNLARRY
LNVEPLFIGEPGLKTGMAVRVRHPEQVGADRIVSALGAHVAYPGDLIVIDSGTATTFDIVSADGAFEGGIISPGIYLSMR
ALHDAAAQLPRIAIQKPPQVIGKDTVSAMQSGVFIGYIELIDGLVRRIKAEWGRPMTVIATGGVASLFEGASETIDYYDQ
DILIRGLLEVWKRNR

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_HYPNA (Q0C1C9)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_760464.1
- ProteinModelPortal:   Q0C1C9
- SMR:   Q0C1C9
- STRING:   Q0C1C9
- GeneID:   4290166
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_1760
- NMPDR:   fig|228405.5.peg.1695
- TIGR:   HNE_1760
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   GTACTIF
- ProtClustDB:   PRK13318
- BioCyc:   HNEP81032:HNE_1760-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27856; Mature: 27856

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: ACT_SITE 110-110 BINDING 133-133 BINDING 185-185

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLVIDVGNTNTVFALHDGEQWVNQWRSATDSTKTADDHASWLWRLADMQGVDLSRVQGC
CEEEEEECCCCEEEEEECCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHH
VVSSVVPHAQFNFRNLARRYLNVEPLFIGEPGLKTGMAVRVRHPEQVGADRIVSALGAHV
HHHHHCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCHHHCHHHHHHHHHHHH
AYPGDLIVIDSGTATTFDIVSADGAFEGGIISPGIYLSMRALHDAAAQLPRIAIQKPPQV
CCCCCEEEEECCCCEEEEEEECCCCCCCCEECCCHHHHHHHHHHHHHHCCHHHHCCCHHH
IGKDTVSAMQSGVFIGYIELIDGLVRRIKAEWGRPMTVIATGGVASLFEGASETIDYYDQ
HHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHCCHHHHHHHHHH
DILIRGLLEVWKRNR
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MLLVIDVGNTNTVFALHDGEQWVNQWRSATDSTKTADDHASWLWRLADMQGVDLSRVQGC
CEEEEEECCCCEEEEEECCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHH
VVSSVVPHAQFNFRNLARRYLNVEPLFIGEPGLKTGMAVRVRHPEQVGADRIVSALGAHV
HHHHHCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCHHHCHHHHHHHHHHHH
AYPGDLIVIDSGTATTFDIVSADGAFEGGIISPGIYLSMRALHDAAAQLPRIAIQKPPQV
CCCCCEEEEECCCCEEEEEEECCCCCCCCEECCCHHHHHHHHHHHHHHCCHHHHCCCHHH
IGKDTVSAMQSGVFIGYIELIDGLVRRIKAEWGRPMTVIATGGVASLFEGASETIDYYDQ
HHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHCCHHHHHHHHHH
DILIRGLLEVWKRNR
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA