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The map label for this gene is pdxJ [H]

Identifier: 114799252

GI number: 114799252

Start: 896584

End: 897327

Strand: Direct

Name: pdxJ [H]

Synonym: HNE_0875

Alternate gene names: 114799252

Gene position: 896584-897327 (Clockwise)

Preceding gene: 114797568

Following gene: 114798027

Centisome position: 24.2

GC content: 66.53

Gene sequence:

>744_bases
ATGACCAGCCGTCTCCGCCTCGGGGTCAATATTGATCATGTGGCGACCATCCGCAACGCGCGCGGAGGCGCCCATCCTGA
TCCGATGCGCGCCGCTGAAATTGCGGCGGCTGCGGGCGCGGACGGCATCACCATCCACCTGCGCGAAGACCGCCGCCACA
TCCGCGACGGAGACCTCGACGCCATTCGCGCGGCGACCCATTTGCCGATCAATCTGGAAATGGCGGCAACCGATGAGATG
ACGGAAATCGCCGTCCGCTTCCGCCCCCATGCCGCCTGTATCGTGCCCGAGCGGCGCGAGGAACGCACCACCGAGGGCGG
CCTGAATGTCGCCGGGCTGCATAACCAGATCGCCCCGATCGTCAGCCGTCTGAATCAGGCGGGCGCGCGCGTCTCGCTCT
TCATTGAGCCCGATCCTGTGCAGATCGCTGTTGCGGAAGTGCTTGGGGCGCCGGTGGTGGAGCTGCACACCGGCCGCTAT
GCAGAGCTCTGGATCGAAGGCGGGGCAGAGGCCGCCGCGCCGGAGCTGGAGCGTCTGAAGCTCGCCGCCGCCGATGCCCG
CCGCCGGGGCATCGAGCCCCATGCCGGCCATGGGCTCACATTTGAAAATGTCGGCCCCGTTGCCGCCATTCCGGAAGTCG
CGGAGCTCAATATCGGCCACTTCCTGATTGGCGAGGCGATCTTCATCGGTCTTGATGCGGCCATCCGCGAAATGCGCCGC
CTGATGGACGAGGCACGGCGATGA

Upstream 100 bases:

>100_bases
CGCTCGCCCAGGTAAACTTTCCCGATTATGCGCCTGATGATCTGCCTCCGGAGCTTCAGAAGATCGAAGCCATCAAGCCC
GGCTCGCGGGGGCTTGCCTG

Downstream 100 bases:

>100_bases
TCATCGGCATCGGCAACGATCTCTGCAATATCGAGCGTATCCAGCGCTCGCTCGACCGGTTCGGCGAGCGCTTCGAGCAG
CGCGTATTCACGCCCCACGA

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTSRLRLGVNIDHVATIRNARGGAHPDPMRAAEIAAAAGADGITIHLREDRRHIRDGDLDAIRAATHLPINLEMAATDEM
TEIAVRFRPHAACIVPERREERTTEGGLNVAGLHNQIAPIVSRLNQAGARVSLFIEPDPVQIAVAEVLGAPVVELHTGRY
AELWIEGGAEAAAPELERLKLAAADARRRGIEPHAGHGLTFENVGPVAAIPEVAELNIGHFLIGEAIFIGLDAAIREMRR
LMDEARR

Sequences:

>Translated_247_residues
MTSRLRLGVNIDHVATIRNARGGAHPDPMRAAEIAAAAGADGITIHLREDRRHIRDGDLDAIRAATHLPINLEMAATDEM
TEIAVRFRPHAACIVPERREERTTEGGLNVAGLHNQIAPIVSRLNQAGARVSLFIEPDPVQIAVAEVLGAPVVELHTGRY
AELWIEGGAEAAAPELERLKLAAADARRRGIEPHAGHGLTFENVGPVAAIPEVAELNIGHFLIGEAIFIGLDAAIREMRR
LMDEARR
>Mature_246_residues
TSRLRLGVNIDHVATIRNARGGAHPDPMRAAEIAAAAGADGITIHLREDRRHIRDGDLDAIRAATHLPINLEMAATDEMT
EIAVRFRPHAACIVPERREERTTEGGLNVAGLHNQIAPIVSRLNQAGARVSLFIEPDPVQIAVAEVLGAPVVELHTGRYA
ELWIEGGAEAAAPELERLKLAAADARRRGIEPHAGHGLTFENVGPVAAIPEVAELNIGHFLIGEAIFIGLDAAIREMRRL
MDEARR

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate [H]

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788917, Length=244, Percent_Identity=54.5081967213115, Blast_Score=251, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR004569 [H]

Pfam domain/function: PF03740 PdxJ [H]

EC number: =2.6.99.2 [H]

Molecular weight: Translated: 26696; Mature: 26565

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRLRLGVNIDHVATIRNARGGAHPDPMRAAEIAAAAGADGITIHLREDRRHIRDGDLD
CCCCEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHH
AIRAATHLPINLEMAATDEMTEIAVRFRPHAACIVPERREERTTEGGLNVAGLHNQIAPI
HHHHHHCCCEEEEECCCCHHHHHHEEECCCEEEECCCHHHHCCCCCCCEEECHHHHHHHH
VSRLNQAGARVSLFIEPDPVQIAVAEVLGAPVVELHTGRYAELWIEGGAEAAAPELERLK
HHHHHHCCCEEEEEECCCCCEEHHHHHHCCCEEEECCCCEEEEEEECCCCCCCCHHHHHH
LAAADARRRGIEPHAGHGLTFENVGPVAAIPEVAELNIGHFLIGEAIFIGLDAAIREMRR
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHEEEHHHHHHHHHH
LMDEARR
HHHHHCC
>Mature Secondary Structure 
TSRLRLGVNIDHVATIRNARGGAHPDPMRAAEIAAAAGADGITIHLREDRRHIRDGDLD
CCCEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHH
AIRAATHLPINLEMAATDEMTEIAVRFRPHAACIVPERREERTTEGGLNVAGLHNQIAPI
HHHHHHCCCEEEEECCCCHHHHHHEEECCCEEEECCCHHHHCCCCCCCEEECHHHHHHHH
VSRLNQAGARVSLFIEPDPVQIAVAEVLGAPVVELHTGRYAELWIEGGAEAAAPELERLK
HHHHHHCCCEEEEEECCCCCEEHHHHHHCCCEEEECCCCEEEEEEECCCCCCCCHHHHHH
LAAADARRRGIEPHAGHGLTFENVGPVAAIPEVAELNIGHFLIGEAIFIGLDAAIREMRR
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHEEEHHHHHHHHHH
LMDEARR
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA