Click here to switch to the map view.

The map label for this gene is acpS

Identifier: 114798027

GI number: 114798027

Start: 897324

End: 897737

Strand: Direct

Name: acpS

Synonym: HNE_0876

Alternate gene names: 114798027

Gene position: 897324-897737 (Clockwise)

Preceding gene: 114799252

Following gene: 114797101

Centisome position: 24.22

GC content: 66.43

Gene sequence:

>414_bases
ATGATCATCGGCATCGGCAACGATCTCTGCAATATCGAGCGTATCCAGCGCTCGCTCGACCGGTTCGGCGAGCGCTTCGA
GCAGCGCGTATTCACGCCCCACGAAATCGCGAAAGCGCGTGGCCGCCGCCGCGTGGCCGAAACCTACGCCAAACGCTTTG
CCGCCAAGGAGGCAATGGCCAAGGCGCTGGGCACAGGTGTGCCGCGCGCGGGCGTCCACTGGAAGCATCTCGGCGTCATC
AATCTCCCCTCCGGCAAGCCGGGCTTTGAACTGACCGGCGGCGCTGCGGCGCGCCTCGCAAAGCTCACCCCGCCAGGCCA
CCGCGCCGTCGTGCATCTGACGCTTACGGACGATCATCCCTGGGCCGAAGCGCAGGTGATCATCGAGGCCATCCCGGTCG
CGGAGCCGTCATGA

Upstream 100 bases:

>100_bases
CGGAGCTCAATATCGGCCACTTCCTGATTGGCGAGGCGATCTTCATCGGTCTTGATGCGGCCATCCGCGAAATGCGCCGC
CTGATGGACGAGGCACGGCG

Downstream 100 bases:

>100_bases
AGCCCGCCCGCCCCAAACGCACACGCCAGCGCGCCGCCGTAAAGGCGGTGAAACCGTCTCTGCCGCCCGAAGCGCTGAAG
GAAGCCCAGGAGATCATCGG

Product: holo-(acyl-carrier-protein) synthase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MIIGIGNDLCNIERIQRSLDRFGERFEQRVFTPHEIAKARGRRRVAETYAKRFAAKEAMAKALGTGVPRAGVHWKHLGVI
NLPSGKPGFELTGGAAARLAKLTPPGHRAVVHLTLTDDHPWAEAQVIIEAIPVAEPS

Sequences:

>Translated_137_residues
MIIGIGNDLCNIERIQRSLDRFGERFEQRVFTPHEIAKARGRRRVAETYAKRFAAKEAMAKALGTGVPRAGVHWKHLGVI
NLPSGKPGFELTGGAAARLAKLTPPGHRAVVHLTLTDDHPWAEAQVIIEAIPVAEPS
>Mature_137_residues
MIIGIGNDLCNIERIQRSLDRFGERFEQRVFTPHEIAKARGRRRVAETYAKRFAAKEAMAKALGTGVPRAGVHWKHLGVI
NLPSGKPGFELTGGAAARLAKLTPPGHRAVVHLTLTDDHPWAEAQVIIEAIPVAEPS

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=129, Percent_Identity=39.5348837209302, Blast_Score=76, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_HYPNA (Q0C3U0)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_759603.1
- ProteinModelPortal:   Q0C3U0
- SMR:   Q0C3U0
- STRING:   Q0C3U0
- GeneID:   4287182
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_0876
- NMPDR:   fig|228405.5.peg.856
- TIGR:   HNE_0876
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- PhylomeDB:   Q0C3U0
- BioCyc:   HNEP81032:HNE_0876-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14975; Mature: 14975

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGIGNDLCNIERIQRSLDRFGERFEQRVFTPHEIAKARGRRRVAETYAKRFAAKEAMA
CEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALGTGVPRAGVHWKHLGVINLPSGKPGFELTGGAAARLAKLTPPGHRAVVHLTLTDDHP
HHHHCCCCCCCCCEEECEEEECCCCCCCCEECCCHHHHHHHCCCCCCEEEEEEEEECCCC
WAEAQVIIEAIPVAEPS
CHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIIGIGNDLCNIERIQRSLDRFGERFEQRVFTPHEIAKARGRRRVAETYAKRFAAKEAMA
CEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALGTGVPRAGVHWKHLGVINLPSGKPGFELTGGAAARLAKLTPPGHRAVVHLTLTDDHP
HHHHCCCCCCCCCEEECEEEECCCCCCCCEECCCHHHHHHHCCCCCCEEEEEEEEECCCC
WAEAQVIIEAIPVAEPS
CHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA