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The map label for this gene is gattA [H]

Identifier: 114799088

GI number: 114799088

Start: 1112899

End: 1114185

Strand: Direct

Name: gattA [H]

Synonym: HNE_1106

Alternate gene names: 114799088

Gene position: 1112899-1114185 (Clockwise)

Preceding gene: 114797886

Following gene: 114798393

Centisome position: 30.04

GC content: 63.56

Gene sequence:

>1287_bases
ATGACACCGATCGAACGCTTCCAGCAGTATGCAGACCGTATCGCGCGGCATAATCCGTCGCTGAATGCGTTTCTCCATCT
GCGTCTGGATGAGGCAAAAGCCGAAGCCCAGGCCGCAGAGGCGCGGCATGTGGTGGGAAAACCGCTTTCGCCAATCGACG
GCTGGTGCTTTGGCATAAAGGCGAACATTGCCGTGAAAGGCCTGCCCCATCATGCGGGGATTGGCGCTTACCGGGACGTG
ATCGCGGCAGAAGATGCCGGGGTCGTGCGCCGGCTGCGCGCGGCGGGCGCGGTGATCCTCGGCATCGTCAACATGCATGA
AGGGGCACTGGGGGCGACGACGGACAATCCCTTCTTCGGGCGAACGCAAAATCCGTGGAAGGAAGGATATACGCCGGGCG
GCTCATCAGGCGGATCGGGCGCGGCGGTTGCCGCCGGGCTCTGCGATGTGGCGCTGGGGTCTGACACGATGGGCTCTGTG
CGCATTCCTTCGGCTTATTGCGGCGTCCAGGGCATCAAGCCGGGCGCCGGGCTGGTTTCCAATGAGGGCGTGCTGGCGCT
TTCGCATACGCTCGATACGGTCGGGCCACATGCGCGCGATGTGTCCAGCCTCCGGGCGGCGCTGTCTGTCATGACCGGGC
AGCCGATGGCGGCGGGTCCCTGCACGCTGAATGGCATGAAGCTCGCCATATGGGATGGCATTGGCCGCGATGGGATGGAA
GATGTTGTTGAGGATGGCTTTGCTGTAGCCGTCTCAAAGATTGAAGCGGCAGGCGCGGAGGCCGATTATGAGGAGCCGTT
CGGTTATCAGTATGGCCGCTCCCGCCGTGCAGGTTTGCTGATTTCCGAGGTCGAAGCGAGTGAAATTCACCGCGAGATGC
TGTCGACTGATCCCGAAGGTTTTTCAGCGCTGTTCCGTAAGCTGATGGCGTGGGGCGTGGCGCGGCCGGCGGAGGAGGTT
GCGCTGGCTTATGAGCATCTCCGCCAGGTGGAGACCGCTGCGGCGCGCGTGTTCGAGGCGCATGACTTCGTGATTGCGCC
CGTAGCACCGCAGACGGCATTTGCGTTTGATACGCCAGCGCCGGAGAATCAGGCGGACTTTACTGCCTGGGCGAACTTCG
CCGGATTGCCTGCGGCGGCTGTCTGTTCCGGGCTGAGCCCGCAAGGGCTGCCGCTGTCGGTCCAGGTGATCGGTCCGAAG
GGATCGGACGCGCGCGTGCTGGATATGGCGCAGGCATTGGAAGCGTTGTTTGGCGCGCCGCGTGTGCCGCTGGCGCTTCA
GCGATAG

Upstream 100 bases:

>100_bases
TTGATGTGGGCGTGGAACTCTCCGGGCCGGGATCGCTTGCCGCACTCACGCAAACTGAAGTACGCCAGAAGCCGATCCGC
CTGATTGACGACCGTTTCAA

Downstream 100 bases:

>100_bases
GTGAATTTGGCCGGGCGTTTATCGAGGAAGGCGCGGTAGCCTTCCTTGAAATCCTCATTCGCGAAGCCGTTGAGGAAGAG
GCTCTGAGCCTCCGGAGTTT

Product: glutamyl-tRNA (Gln) amidotransferase subunit A

Products: NA

Alternate protein names: Glu-ADT subunit A [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MTPIERFQQYADRIARHNPSLNAFLHLRLDEAKAEAQAAEARHVVGKPLSPIDGWCFGIKANIAVKGLPHHAGIGAYRDV
IAAEDAGVVRRLRAAGAVILGIVNMHEGALGATTDNPFFGRTQNPWKEGYTPGGSSGGSGAAVAAGLCDVALGSDTMGSV
RIPSAYCGVQGIKPGAGLVSNEGVLALSHTLDTVGPHARDVSSLRAALSVMTGQPMAAGPCTLNGMKLAIWDGIGRDGME
DVVEDGFAVAVSKIEAAGAEADYEEPFGYQYGRSRRAGLLISEVEASEIHREMLSTDPEGFSALFRKLMAWGVARPAEEV
ALAYEHLRQVETAAARVFEAHDFVIAPVAPQTAFAFDTPAPENQADFTAWANFAGLPAAAVCSGLSPQGLPLSVQVIGPK
GSDARVLDMAQALEALFGAPRVPLALQR

Sequences:

>Translated_428_residues
MTPIERFQQYADRIARHNPSLNAFLHLRLDEAKAEAQAAEARHVVGKPLSPIDGWCFGIKANIAVKGLPHHAGIGAYRDV
IAAEDAGVVRRLRAAGAVILGIVNMHEGALGATTDNPFFGRTQNPWKEGYTPGGSSGGSGAAVAAGLCDVALGSDTMGSV
RIPSAYCGVQGIKPGAGLVSNEGVLALSHTLDTVGPHARDVSSLRAALSVMTGQPMAAGPCTLNGMKLAIWDGIGRDGME
DVVEDGFAVAVSKIEAAGAEADYEEPFGYQYGRSRRAGLLISEVEASEIHREMLSTDPEGFSALFRKLMAWGVARPAEEV
ALAYEHLRQVETAAARVFEAHDFVIAPVAPQTAFAFDTPAPENQADFTAWANFAGLPAAAVCSGLSPQGLPLSVQVIGPK
GSDARVLDMAQALEALFGAPRVPLALQR
>Mature_427_residues
TPIERFQQYADRIARHNPSLNAFLHLRLDEAKAEAQAAEARHVVGKPLSPIDGWCFGIKANIAVKGLPHHAGIGAYRDVI
AAEDAGVVRRLRAAGAVILGIVNMHEGALGATTDNPFFGRTQNPWKEGYTPGGSSGGSGAAVAAGLCDVALGSDTMGSVR
IPSAYCGVQGIKPGAGLVSNEGVLALSHTLDTVGPHARDVSSLRAALSVMTGQPMAAGPCTLNGMKLAIWDGIGRDGMED
VVEDGFAVAVSKIEAAGAEADYEEPFGYQYGRSRRAGLLISEVEASEIHREMLSTDPEGFSALFRKLMAWGVARPAEEVA
LAYEHLRQVETAAARVFEAHDFVIAPVAPQTAFAFDTPAPENQADFTAWANFAGLPAAAVCSGLSPQGLPLSVQVIGPKG
SDARVLDMAQALEALFGAPRVPLALQR

Specific function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activa

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI195972892, Length=466, Percent_Identity=26.6094420600858, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI222831590, Length=495, Percent_Identity=26.2626262626263, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI166795287, Length=198, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17543272, Length=386, Percent_Identity=28.2383419689119, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17556264, Length=165, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17537465, Length=458, Percent_Identity=24.6724890829694, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17538252, Length=188, Percent_Identity=32.4468085106383, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17556276, Length=139, Percent_Identity=35.2517985611511, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17556278, Length=139, Percent_Identity=35.2517985611511, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71990152, Length=170, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319685, Length=389, Percent_Identity=28.2776349614396, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323950, Length=168, Percent_Identity=36.9047619047619, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24648113, Length=456, Percent_Identity=30.9210526315789, Blast_Score=141, Evalue=9e-34,
Organism=Drosophila melanogaster, GI24644968, Length=481, Percent_Identity=27.027027027027, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI45550774, Length=453, Percent_Identity=26.9315673289183, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24648435, Length=453, Percent_Identity=26.9315673289183, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24648437, Length=453, Percent_Identity=26.9315673289183, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24652985, Length=468, Percent_Identity=27.1367521367521, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI19922090, Length=468, Percent_Identity=27.1367521367521, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24652981, Length=468, Percent_Identity=27.1367521367521, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24652983, Length=468, Percent_Identity=27.1367521367521, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21356731, Length=456, Percent_Identity=25.4385964912281, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24648441, Length=402, Percent_Identity=27.1144278606965, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24648439, Length=402, Percent_Identity=27.1144278606965, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI161078093, Length=481, Percent_Identity=27.027027027027, Blast_Score=105, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556
- InterPro:   IPR004412 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: 6.3.5.-

Molecular weight: Translated: 44825; Mature: 44694

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPIERFQQYADRIARHNPSLNAFLHLRLDEAKAEAQAAEARHVVGKPLSPIDGWCFGIK
CCHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
ANIAVKGLPHHAGIGAYRDVIAAEDAGVVRRLRAAGAVILGIVNMHEGALGATTDNPFFG
ECEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHCCEEEEEEHHHCCCCCCCCCCCCCCC
RTQNPWKEGYTPGGSSGGSGAAVAAGLCDVALGSDTMGSVRIPSAYCGVQGIKPGAGLVS
CCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCHHHCCCCCCCCCCCEEC
NEGVLALSHTLDTVGPHARDVSSLRAALSVMTGQPMAAGPCTLNGMKLAIWDGIGRDGME
CCCEEEEECHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHH
DVVEDGFAVAVSKIEAAGAEADYEEPFGYQYGRSRRAGLLISEVEASEIHREMLSTDPEG
HHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCHH
FSALFRKLMAWGVARPAEEVALAYEHLRQVETAAARVFEAHDFVIAPVAPQTAFAFDTPA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCC
PENQADFTAWANFAGLPAAAVCSGLSPQGLPLSVQVIGPKGSDARVLDMAQALEALFGAP
CCCCCCHHHHHHCCCCCHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCC
RVPLALQR
CCCEECCC
>Mature Secondary Structure 
TPIERFQQYADRIARHNPSLNAFLHLRLDEAKAEAQAAEARHVVGKPLSPIDGWCFGIK
CHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
ANIAVKGLPHHAGIGAYRDVIAAEDAGVVRRLRAAGAVILGIVNMHEGALGATTDNPFFG
ECEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHCCEEEEEEHHHCCCCCCCCCCCCCCC
RTQNPWKEGYTPGGSSGGSGAAVAAGLCDVALGSDTMGSVRIPSAYCGVQGIKPGAGLVS
CCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCHHHCCCCCCCCCCCEEC
NEGVLALSHTLDTVGPHARDVSSLRAALSVMTGQPMAAGPCTLNGMKLAIWDGIGRDGME
CCCEEEEECHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHH
DVVEDGFAVAVSKIEAAGAEADYEEPFGYQYGRSRRAGLLISEVEASEIHREMLSTDPEG
HHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCHH
FSALFRKLMAWGVARPAEEVALAYEHLRQVETAAARVFEAHDFVIAPVAPQTAFAFDTPA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCC
PENQADFTAWANFAGLPAAAVCSGLSPQGLPLSVQVIGPKGSDARVLDMAQALEALFGAP
CCCCCCHHHHHHCCCCCHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCC
RVPLALQR
CCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA