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The map label for this gene is paaK [H]

Identifier: 114797886

GI number: 114797886

Start: 1111553

End: 1112902

Strand: Direct

Name: paaK [H]

Synonym: HNE_1105

Alternate gene names: 114797886

Gene position: 1111553-1112902 (Clockwise)

Preceding gene: 114797367

Following gene: 114799088

Centisome position: 30.0

GC content: 60.81

Gene sequence:

>1350_bases
ATGCAGGAAGAACATCCCGTAGGGGACGCGTTCCTGACATTTGCCAAAAAGAGCCGCGATGAAATCCGCGCGCATCAGGA
GAAGCTGTTTGCGCGCCTCGTGGACCGGGCCTGGAAGACGAAATTCTACCAGCACCATTGGGGCAAGGCAGGCGTAGAGC
CGGGCGACATCAAGGGGCTTGAGACGCTGCCCAGCCTGCCGAGCTTTGACAAGAGCGACATCATGGAGTCGATCGCGCGC
AATCCGCCGCTGGGCGACTTCGCAGGCTTTGAAAGCTATGGTCCGGGCGAGCGCCCGCCGGCCATCATGCACACGACTTC
TGGCACAACGGGCACGCCGCAGGTTCTGCTGTTCGGCGCAAAGTCGCGCGAAGTTCAGAACCTGCTACTGGGCCGGCTTT
ACCGCTTCCAGGGACTGCGCCCGGACGACGTGATCCATTCCGTTTACGGACATGGCATGATCAATGGCGGGCATTATGTG
CGCGAAGCGGTAACACACTGGACGAGCTCGCTGTTCCTCTCTGCCGGTACGGGCGTCGAGACGCCATCGGTCAAGCAGGT
GCAGCTGATGAAGGATTTCGGCGCGACCGTGATTGTCGGCTTTGCCGACTATATCAAGAAACTCGCCCGCGTGGCCGTGG
AGCAGGGCCTGGACCCCGTGAAGGATCTGAACATCCGCATGATTTCCGGCCACCTTGGCCGGGAGGACAAGGAAACGCTG
TCGCAGGCCTGGGGCGGGGCGGCGTGTTTTGACTGGTATGGCGTGGGCGATACCGGCTGTATCGCCGGCGAAGGCCCGGA
CCGGGACGGCCTCTACATCATGGAAGACGCGCAATTCCTGGAGATTGGCGACATCGACACGGGCAAGCCCGTGGCGGAAG
GCGCTGAAGGCGACATGATCTGCACCTGTCTGTTCAAGGATGATCTCTATCCCATCATCCGGTTCAACACGCATGATGTT
ACCCGTCTGCGCACCGGCGCCTCCAGCCTCGGGATCAATTTCCAGCGGATTGAGGGTTTCCTTGGCCGGTCTGACAACAT
GGTGAAAATCCGCGGGATCAACATTTTCCCGCAGGCGATGGGGCCGATCCTTGAGGAAGACGCCGCCTTTGCGGGCGAAT
TCATCTGCAAGGCCAAGCGCGATGAAAGCGGCCGGGACGAGTTTATCGTGGCGGCCGAAGTGAATGGCGGCGCCAGCGAA
GCGGTGGCCGATCGCTTCCGCGCATTGCTGAAGCAGAAGATCGGGATTGATGTGGGCGTGGAACTCTCCGGGCCGGGATC
GCTTGCCGCACTCACGCAAACTGAAGTACGCCAGAAGCCGATCCGCCTGATTGACGACCGTTTCAAATGA

Upstream 100 bases:

>100_bases
GAGGATGCCGGGCGGCTTTCCCGCCTTGCGTCTGGTATAATGGAGTGATCCGATGACGGATGGACATAACACATACTTCA
ATACGGTCGACTGGGCAAAG

Downstream 100 bases:

>100_bases
CACCGATCGAACGCTTCCAGCAGTATGCAGACCGTATCGCGCGGCATAATCCGTCGCTGAATGCGTTTCTCCATCTGCGT
CTGGATGAGGCAAAAGCCGA

Product: putative aerobic phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MQEEHPVGDAFLTFAKKSRDEIRAHQEKLFARLVDRAWKTKFYQHHWGKAGVEPGDIKGLETLPSLPSFDKSDIMESIAR
NPPLGDFAGFESYGPGERPPAIMHTTSGTTGTPQVLLFGAKSREVQNLLLGRLYRFQGLRPDDVIHSVYGHGMINGGHYV
REAVTHWTSSLFLSAGTGVETPSVKQVQLMKDFGATVIVGFADYIKKLARVAVEQGLDPVKDLNIRMISGHLGREDKETL
SQAWGGAACFDWYGVGDTGCIAGEGPDRDGLYIMEDAQFLEIGDIDTGKPVAEGAEGDMICTCLFKDDLYPIIRFNTHDV
TRLRTGASSLGINFQRIEGFLGRSDNMVKIRGINIFPQAMGPILEEDAAFAGEFICKAKRDESGRDEFIVAAEVNGGASE
AVADRFRALLKQKIGIDVGVELSGPGSLAALTQTEVRQKPIRLIDDRFK

Sequences:

>Translated_449_residues
MQEEHPVGDAFLTFAKKSRDEIRAHQEKLFARLVDRAWKTKFYQHHWGKAGVEPGDIKGLETLPSLPSFDKSDIMESIAR
NPPLGDFAGFESYGPGERPPAIMHTTSGTTGTPQVLLFGAKSREVQNLLLGRLYRFQGLRPDDVIHSVYGHGMINGGHYV
REAVTHWTSSLFLSAGTGVETPSVKQVQLMKDFGATVIVGFADYIKKLARVAVEQGLDPVKDLNIRMISGHLGREDKETL
SQAWGGAACFDWYGVGDTGCIAGEGPDRDGLYIMEDAQFLEIGDIDTGKPVAEGAEGDMICTCLFKDDLYPIIRFNTHDV
TRLRTGASSLGINFQRIEGFLGRSDNMVKIRGINIFPQAMGPILEEDAAFAGEFICKAKRDESGRDEFIVAAEVNGGASE
AVADRFRALLKQKIGIDVGVELSGPGSLAALTQTEVRQKPIRLIDDRFK
>Mature_449_residues
MQEEHPVGDAFLTFAKKSRDEIRAHQEKLFARLVDRAWKTKFYQHHWGKAGVEPGDIKGLETLPSLPSFDKSDIMESIAR
NPPLGDFAGFESYGPGERPPAIMHTTSGTTGTPQVLLFGAKSREVQNLLLGRLYRFQGLRPDDVIHSVYGHGMINGGHYV
REAVTHWTSSLFLSAGTGVETPSVKQVQLMKDFGATVIVGFADYIKKLARVAVEQGLDPVKDLNIRMISGHLGREDKETL
SQAWGGAACFDWYGVGDTGCIAGEGPDRDGLYIMEDAQFLEIGDIDTGKPVAEGAEGDMICTCLFKDDLYPIIRFNTHDV
TRLRTGASSLGINFQRIEGFLGRSDNMVKIRGINIFPQAMGPILEEDAAFAGEFICKAKRDESGRDEFIVAAEVNGGASE
AVADRFRALLKQKIGIDVGVELSGPGSLAALTQTEVRQKPIRLIDDRFK

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=436, Percent_Identity=27.2935779816514, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 49252; Mature: 49252

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEEHPVGDAFLTFAKKSRDEIRAHQEKLFARLVDRAWKTKFYQHHWGKAGVEPGDIKGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
ETLPSLPSFDKSDIMESIARNPPLGDFAGFESYGPGERPPAIMHTTSGTTGTPQVLLFGA
HHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEECC
KSREVQNLLLGRLYRFQGLRPDDVIHSVYGHGMINGGHYVREAVTHWTSSLFLSAGTGVE
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHEECCCCCC
TPSVKQVQLMKDFGATVIVGFADYIKKLARVAVEQGLDPVKDLNIRMISGHLGREDKETL
CCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCHHCCCEEEEECCCCCCHHHHH
SQAWGGAACFDWYGVGDTGCIAGEGPDRDGLYIMEDAQFLEIGDIDTGKPVAEGAEGDMI
HHHCCCEEEEEEECCCCCCEECCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCCCCCEE
CTCLFKDDLYPIIRFNTHDVTRLRTGASSLGINFQRIEGFLGRSDNMVKIRGINIFPQAM
EEEEECCCCCEEEEECCCCHHHHHCCHHHHCCCHHHHHHHHCCCCCEEEEECCEECHHHH
GPILEEDAAFAGEFICKAKRDESGRDEFIVAAEVNGGASEAVADRFRALLKQKIGIDVGV
CCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEE
ELSGPGSLAALTQTEVRQKPIRLIDDRFK
EECCCCCEEHHHHHHHHHCCHHHHHCCCC
>Mature Secondary Structure
MQEEHPVGDAFLTFAKKSRDEIRAHQEKLFARLVDRAWKTKFYQHHWGKAGVEPGDIKGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
ETLPSLPSFDKSDIMESIARNPPLGDFAGFESYGPGERPPAIMHTTSGTTGTPQVLLFGA
HHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEECC
KSREVQNLLLGRLYRFQGLRPDDVIHSVYGHGMINGGHYVREAVTHWTSSLFLSAGTGVE
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHEECCCCCC
TPSVKQVQLMKDFGATVIVGFADYIKKLARVAVEQGLDPVKDLNIRMISGHLGREDKETL
CCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCHHCCCEEEEECCCCCCHHHHH
SQAWGGAACFDWYGVGDTGCIAGEGPDRDGLYIMEDAQFLEIGDIDTGKPVAEGAEGDMI
HHHCCCEEEEEEECCCCCCEECCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCCCCCEE
CTCLFKDDLYPIIRFNTHDVTRLRTGASSLGINFQRIEGFLGRSDNMVKIRGINIFPQAM
EEEEECCCCCEEEEECCCCHHHHHCCHHHHCCCHHHHHHHHCCCCCEEEEECCEECHHHH
GPILEEDAAFAGEFICKAKRDESGRDEFIVAAEVNGGASEAVADRFRALLKQKIGIDVGV
CCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEE
ELSGPGSLAALTQTEVRQKPIRLIDDRFK
EECCCCCEEHHHHHHHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]