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The map label for this gene is nudF [H]

Identifier: 114798768

GI number: 114798768

Start: 2945418

End: 2945864

Strand: Direct

Name: nudF [H]

Synonym: HNE_2782

Alternate gene names: 114798768

Gene position: 2945418-2945864 (Clockwise)

Preceding gene: 114799366

Following gene: 114797788

Centisome position: 79.5

GC content: 69.8

Gene sequence:

>447_bases
ATGACCGTGCCCGCCGCCCCGCTGCCCGGCCGGCCGACGCCCGCCGTCGGCGCCGTCTGTTTCAAAGGCGAAGACGTACT
CCTCATCCGGCGCGGTACGCCCCCGCTCGCCGGTGACTGGTCGATCCCCGGCGGCCGCATCGAATTTGGCGAGCGTACAG
AGGCCGCCGCTCTGCGCGAGTTGATGGAAGAAACCGGCGTCACCGCCCGCCTCATCGGCCTCGTCGATGTCGTCGACGCG
ATCTTCACCTCACGCGCTTCGGGCGACGTCACACGCCACTATCTGCTGTTCGACTTTGCCGCCGTCTGGCTCTCGGGCGA
CCCGGTGGCGGGCGACGATGCCAGCCATGCCGAATGGGTCTCGCCCGAGCGGCTAGCCGCCATCGCCCTCTGGGAGGAGA
CCCGCCGGATCATCGAAGCGGCCCGCGCGATGGTCTCAGCGCTCTGA

Upstream 100 bases:

>100_bases
GCGCCCTCGTCGATGGCGGCTACCGCCTCCTGCGCGCCCATCCGGTCGACCAGTTCCTCTGGTCGGCGCATGTCGAAGCC
GTCGCGCTGCTGGAAAAGCC

Downstream 100 bases:

>100_bases
AAAACGCCAACCACCCGGAGCCCCGTTGGAGTTTTTGGGCCCCTCATTGGAGGAATCGTTGGAGTTTTTTGCGCTCCTTA
TCCCCCGTTTATTTTCCTTG

Product: NUDIX family NudH subfamily hydrolase

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MTVPAAPLPGRPTPAVGAVCFKGEDVLLIRRGTPPLAGDWSIPGGRIEFGERTEAAALRELMEETGVTARLIGLVDVVDA
IFTSRASGDVTRHYLLFDFAAVWLSGDPVAGDDASHAEWVSPERLAAIALWEETRRIIEAARAMVSAL

Sequences:

>Translated_148_residues
MTVPAAPLPGRPTPAVGAVCFKGEDVLLIRRGTPPLAGDWSIPGGRIEFGERTEAAALRELMEETGVTARLIGLVDVVDA
IFTSRASGDVTRHYLLFDFAAVWLSGDPVAGDDASHAEWVSPERLAAIALWEETRRIIEAARAMVSAL
>Mature_147_residues
TVPAAPLPGRPTPAVGAVCFKGEDVLLIRRGTPPLAGDWSIPGGRIEFGERTEAAALRELMEETGVTARLIGLVDVVDAI
FTSRASGDVTRHYLLFDFAAVWLSGDPVAGDDASHAEWVSPERLAAIALWEETRRIIEAARAMVSAL

Specific function: Involved In The Go System Responsible For Removing An Oxidatively Damaged Form Of Guanine (7,8-Dihydro-8-Oxoguanine) From DNA And The Nucleotide Pool. 8-Oxo-Dgtp Is Inserted Opposite Da And Dc Residues Of Template DNA With Almost Equal Efficiency Thus Le

COG id: COG1051

COG function: function code F; ADP-ribose pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 15822; Mature: 15691

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVPAAPLPGRPTPAVGAVCFKGEDVLLIRRGTPPLAGDWSIPGGRIEFGERTEAAALRE
CCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCEEECCCCHHHHHHHH
LMEETGVTARLIGLVDVVDAIFTSRASGDVTRHYLLFDFAAVWLSGDPVAGDDASHAEWV
HHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SPERLAAIALWEETRRIIEAARAMVSAL
CHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVPAAPLPGRPTPAVGAVCFKGEDVLLIRRGTPPLAGDWSIPGGRIEFGERTEAAALRE
CCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCEEECCCCHHHHHHHH
LMEETGVTARLIGLVDVVDAIFTSRASGDVTRHYLLFDFAAVWLSGDPVAGDDASHAEWV
HHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SPERLAAIALWEETRRIIEAARAMVSAL
CHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 9694840 [H]