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The map label for this gene is ygcA [C]

Identifier: 114799366

GI number: 114799366

Start: 2944171

End: 2945421

Strand: Direct

Name: ygcA [C]

Synonym: HNE_2781

Alternate gene names: 114799366

Gene position: 2944171-2945421 (Clockwise)

Preceding gene: 114800273

Following gene: 114798768

Centisome position: 79.46

GC content: 70.74

Gene sequence:

>1251_bases
ATGCCCCCGCCTGCCGCGCCCCTGCGCACGCTCACCATCGACCATGTTGGCGCCCAGGGCGATGGCCGCGCGCGGGAGGG
AGACCGCTGGGTGTCTGTGCCGTTCACTCTCGCCGGCGAGGTCGTCGAAGTCAGCGGCGAGGGCGACCGGCTGAGGCTGG
AGCGGATATCCTCGCCGTCCTCTGAGCGCACAGCCCCGTCCTGCCGCCACTTCACCCGCTGTGGCGGCTGCACGCTGCAA
CACATGGCGCCCGCCCCCTATGCCGCCTTCAAGCGAGACCTGATCGTCCGTGCCCTGAAAACACGCGGCCTGGAGGCAGA
GGTTACCGAGACCTGGATCACCCCGCCCGCTTCCCGCCGCCGCGCGACCTTCACCGCCCGCAAATCGGGCAAGACCATCA
TGGTCGGCTTTCATGGCCGCAAGAGCCATGAGCTGATCGCGCTGGAAGAATGCCCCGTGGCCCGCCCCGCCATCGTCGCC
GCCCTGCCAAAGCTGGCCGGCATCCTCGCCCCGCTTTTCAGCGGCAAGGAAGACCTCAGCCTCCTCGTCACCGAAACCGC
CTCGGGCCTCGACCTGCATGTGACGGGCATTCCCAAACAGGCCACCCGCCTTGCCCGCGCCGAAGTCACCAGCGCTGCCC
TGCGGGCCGGCTTCGCCCGTGTCTCCCTCGAGGGCGAAGACGTGCTGACCGAGCGCCCCCCGCGCCTGCCCATCGGCGCG
GCCAGTCTCCTGCCCCCGCCCGGCGGCTTCCTGCAGGCCAGCGCCGAGGCGGAGACCGAAATCGCCCGCCTCGTGCTCGG
CCATCTCGGCGGCGCAAAACACGCCGCCGATCTTTTCTCCGGCTGCGGAACATTTGCCCTGCGCCTGGCAGAGCGCATTC
CGGTCTTCGCTGCCGAAAGCGGGCGCCCCGCCATCGAGGCCCTGCGCGCCGCCGCCAATGCCGCTCCCGGCCTCAAACCC
GTCACCGCCGATGTGAGAGACCTCTTCCGCAATCCCCTCGCTGCGGTCGAGTTGGCCCGGTTTGACGGTCTCGTGCTGGA
TCCCCCGCGCGCGGGCGCCTCGGCGCAGGCGGCCGAAATCGCCCGCTCCACCGTGCCGCGCGTCGCCTATGTCTCCTGCG
ATCCCGCCACCCTCGCCCGCGACCTGCGCGCCCTCGTCGATGGCGGCTACCGCCTCCTGCGCGCCCATCCGGTCGACCAG
TTCCTCTGGTCGGCGCATGTCGAAGCCGTCGCGCTGCTGGAAAAGCCATGA

Upstream 100 bases:

>100_bases
ACTGGCTTTTGCCATGCCCCGGCTCCTTTCGGTTGCGCCCTGTCCCTGCTAACGGAGGACACCGAAACCCGCCACCCCTC
ACACGCCGCCTGGAGATCAG

Downstream 100 bases:

>100_bases
CCGTGCCCGCCGCCCCGCTGCCCGGCCGGCCGACGCCCGCCGTCGGCGCCGTCTGTTTCAAAGGCGAAGACGTACTCCTC
ATCCGGCGCGGTACGCCCCC

Product: putative 23S rRNA (uracil-5-)-methyltransferase RumA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MPPPAAPLRTLTIDHVGAQGDGRAREGDRWVSVPFTLAGEVVEVSGEGDRLRLERISSPSSERTAPSCRHFTRCGGCTLQ
HMAPAPYAAFKRDLIVRALKTRGLEAEVTETWITPPASRRRATFTARKSGKTIMVGFHGRKSHELIALEECPVARPAIVA
ALPKLAGILAPLFSGKEDLSLLVTETASGLDLHVTGIPKQATRLARAEVTSAALRAGFARVSLEGEDVLTERPPRLPIGA
ASLLPPPGGFLQASAEAETEIARLVLGHLGGAKHAADLFSGCGTFALRLAERIPVFAAESGRPAIEALRAAANAAPGLKP
VTADVRDLFRNPLAAVELARFDGLVLDPPRAGASAQAAEIARSTVPRVAYVSCDPATLARDLRALVDGGYRLLRAHPVDQ
FLWSAHVEAVALLEKP

Sequences:

>Translated_416_residues
MPPPAAPLRTLTIDHVGAQGDGRAREGDRWVSVPFTLAGEVVEVSGEGDRLRLERISSPSSERTAPSCRHFTRCGGCTLQ
HMAPAPYAAFKRDLIVRALKTRGLEAEVTETWITPPASRRRATFTARKSGKTIMVGFHGRKSHELIALEECPVARPAIVA
ALPKLAGILAPLFSGKEDLSLLVTETASGLDLHVTGIPKQATRLARAEVTSAALRAGFARVSLEGEDVLTERPPRLPIGA
ASLLPPPGGFLQASAEAETEIARLVLGHLGGAKHAADLFSGCGTFALRLAERIPVFAAESGRPAIEALRAAANAAPGLKP
VTADVRDLFRNPLAAVELARFDGLVLDPPRAGASAQAAEIARSTVPRVAYVSCDPATLARDLRALVDGGYRLLRAHPVDQ
FLWSAHVEAVALLEKP
>Mature_415_residues
PPPAAPLRTLTIDHVGAQGDGRAREGDRWVSVPFTLAGEVVEVSGEGDRLRLERISSPSSERTAPSCRHFTRCGGCTLQH
MAPAPYAAFKRDLIVRALKTRGLEAEVTETWITPPASRRRATFTARKSGKTIMVGFHGRKSHELIALEECPVARPAIVAA
LPKLAGILAPLFSGKEDLSLLVTETASGLDLHVTGIPKQATRLARAEVTSAALRAGFARVSLEGEDVLTERPPRLPIGAA
SLLPPPGGFLQASAEAETEIARLVLGHLGGAKHAADLFSGCGTFALRLAERIPVFAAESGRPAIEALRAAANAAPGLKPV
TADVRDLFRNPLAAVELARFDGLVLDPPRAGASAQAAEIARSTVPRVAYVSCDPATLARDLRALVDGGYRLLRAHPVDQF
LWSAHVEAVALLEKP

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RNA M5U methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789148, Length=421, Percent_Identity=27.5534441805226, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1790403, Length=235, Percent_Identity=27.6595744680851, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 44091; Mature: 43960

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPPAAPLRTLTIDHVGAQGDGRAREGDRWVSVPFTLAGEVVEVSGEGDRLRLERISSPS
CCCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCEEECCCEEEECCCCCEEEEEECCCCC
SERTAPSCRHFTRCGGCTLQHMAPAPYAAFKRDLIVRALKTRGLEAEVTETWITPPASRR
CCCCCCHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCC
RATFTARKSGKTIMVGFHGRKSHELIALEECPVARPAIVAALPKLAGILAPLFSGKEDLS
CEEEEEECCCCEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCE
LLVTETASGLDLHVTGIPKQATRLARAEVTSAALRAGFARVSLEGEDVLTERPPRLPIGA
EEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHCCCCCCCCCCC
ASLLPPPGGFLQASAEAETEIARLVLGHLGGAKHAADLFSGCGTFALRLAERIPVFAAES
HHCCCCCCCCEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECC
GRPAIEALRAAANAAPGLKPVTADVRDLFRNPLAAVELARFDGLVLDPPRAGASAQAAEI
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCEEECCCCCCCCHHHHHH
ARSTVPRVAYVSCDPATLARDLRALVDGGYRLLRAHPVDQFLWSAHVEAVALLEKP
HHHCCCCEEEEECCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHEECCC
>Mature Secondary Structure 
PPPAAPLRTLTIDHVGAQGDGRAREGDRWVSVPFTLAGEVVEVSGEGDRLRLERISSPS
CCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCEEECCCEEEECCCCCEEEEEECCCCC
SERTAPSCRHFTRCGGCTLQHMAPAPYAAFKRDLIVRALKTRGLEAEVTETWITPPASRR
CCCCCCHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCC
RATFTARKSGKTIMVGFHGRKSHELIALEECPVARPAIVAALPKLAGILAPLFSGKEDLS
CEEEEEECCCCEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCE
LLVTETASGLDLHVTGIPKQATRLARAEVTSAALRAGFARVSLEGEDVLTERPPRLPIGA
EEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHCCCCCCCCCCC
ASLLPPPGGFLQASAEAETEIARLVLGHLGGAKHAADLFSGCGTFALRLAERIPVFAAES
HHCCCCCCCCEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECC
GRPAIEALRAAANAAPGLKPVTADVRDLFRNPLAAVELARFDGLVLDPPRAGASAQAAEI
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCEEECCCCCCCCHHHHHH
ARSTVPRVAYVSCDPATLARDLRALVDGGYRLLRAHPVDQFLWSAHVEAVALLEKP
HHHCCCCEEEEECCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]