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The map label for this gene is cirA [H]

Identifier: 114798760

GI number: 114798760

Start: 3527048

End: 3529534

Strand: Direct

Name: cirA [H]

Synonym: HNE_3381

Alternate gene names: 114798760

Gene position: 3527048-3529534 (Clockwise)

Preceding gene: 114799156

Following gene: 114799337

Centisome position: 95.2

GC content: 62.65

Gene sequence:

>2487_bases
ATGAAATTCAAAGTAGCGTTATCTGCGGCCGTTGCCGCAATCGCCCTTTCTGCAGTGTCTGCACCAGTCATGGCGCAAGA
GCAGGAAGATGAGGCGGCCCGCACGCTCGACACCGTCGTCACAGTCGGTACCCGCGTCGCCAACCGGTCTGCCCTCGATA
CCGCCGCCCCGGTAGACGTGGTCTCGTCCGAAGCCATTCAGAACATCGGTGTTGGCGAACTCAACCAGTCCCTGTCGGTA
AACCTGCCGGCCCTCAACTTCCCCCGCCCTGCCCTGACCGACGGCACCGACTCGGTGCGTCCCGCAGCGCTTCGCGGCCT
TTCCCCGGACCAGACCCTCGTGCTGGTCAATGGCAAACGCCGCCACACCGCCTCGCTGGTCAACGTCAACGGCTCGATCG
GCCGCGGCGCATCGGCGGTTGACCTCAACACCATCCCCAACCTGGCTGTCGGCGGCGTCGAAGTGCTGCGCGACGGCGCC
TCTGCCCTTTATGGCTCTGACGCCATCGCCGGCGTGGTCAACGTGCGTCTGCGCGAAGCCAATACGGGCGGCGCTGTTTC
GGTAAGCTATGGCTGGCGCGAGACGGAATACACGACGCCTGTGGTCGCTCCGACTGCGGCTGGCGTGCCGGATCCCGGCC
GCGAAGTTACCCGTGAACGCTCGGACGGCCATGTGGCAACCGTTGCCGGCTGGAAGGGCTTTTCCCTCGGCCAGGACGGC
TTCCTCACCCTCACCGGCGAGTACAAGGACCAGAACCACACCGAGCGCTCCGGCTACGACTTCCGCCAGCAGTATCCGGG
CAGCCAGCCCGCTGCAGAAGCCGAAATCGGCCGCTTCAACGCCTGGACCGGTGAACCCGATCTTGAGCAGATCAGCCTCT
TCGCCAATGCCGGCTACGGCCTCGCAAATGGCGCAGAACTTTATGGCTGGGCCAGCTTCCAGGACCGCGAGACCGTCTCG
GCCGGCTTCTTCCGCCGCGCGCTGGACGATCGCAACACGATTGAAATCTATCCCAACGGCTTCCTGCCGAAGATCAACCC
GACGACCACGGACTATTCTGCCCTCGGCGGTATCCGGTTCGACTTCGCGGGTTGGGATGCTGACGCGTCGCTCGGCTACG
GCTCCAACAAAATGGAATTCCAGATCATCGACACGCTGAACCGTTCGCTCGGCACCGCGTCGGGCACGGAATTCGATGCC
GGCGGTTTCGAGCACTCCCAGCTCGTCGCCAATATCGGCTTTGTGAAAGGCTTCGCGGTTGACGGCCTCGCCTCTGATCT
GAACGTCGCCTGGGGCGCTGAAGCCCGCCAGGAAAACTATGAAATCTTCGCTGGTGAGCCGGACTCCTACCGCAATGGCG
GCGTGCTTCTGCCAGGTGGCGGCTCGACCGCTTCGGGCGCGCAGGTGTTCCCCGGCTTCCAGCCTGCGAACGAACTCGAA
GAAGACCGCACGGCTGTTGGCGTCTATCTCGACGTTGAAGCCAACGTCACGGACGCGCTTCTTCTGTCGGGCGCTGTGCG
CGGCGAATCCTACTCGGATTTCGGCGAGGCACTCACCGGTAAACTGGCCGCGCGTTATGACTTCAACGACGCCTTCGCGC
TTCGCGGGTCTATCCAGAACGGTTTCCGCGCGCCTTCGCTGCAGCAGCAATACTACACCACCACGTCGACCAACTTCATC
AACGGCGTGCCGTTTGATGTCACGACCTTCCGGGTGGACGATCCGATTGCCCGCGCTCTCGGCGCCCAGGACCTCGATGC
CGAGAAGTCGATCAACTACGCAATCGGCGCAGTCTTCCAGGCCGGTGCCTTCAACATGACGGTCGATGCTTACCGCATCG
ATGTGGAAGATCGCATCGTGCTGTCGGAAAACCTGACGGCAGGCAATGTGCAGGATTTCCTCGTGTCCCAGGGCTTCATC
GGCTCGGGCGGCGGCCGTTTCTTCATCAACGGTGTTGAAACGGAAACAACCGGCGTCGACATCATCGCCAACTACGCCTT
CCCGGAAACCGAGTTCGGCTCGTTCACCGCGACCGCAGGGGCCAACTTCAACAAGACTGAAGTGACCGGTGTTCCAGCGA
TCCCGGTCCTGACGGGGCTCACGCCACCGCCGGTCCTTTTCGCGCGCACCAACATCCTCACGCTTGAGGAAGGCACGCCG
AAGGACAAGTTCACCGGCCAGGTGAACTGGGAGCATGGTCCGTTCGCGGGTACGCTGCGCGCCGTGCGTTACGGTGAAGT
GCTGGTGCCATCGAACACGCCGGCACTGGACTATACGCTCGACCCCCAGACCCTTATCGATCTGGAAGCGCGCTATACCT
GGAACGACATGCTGACGCTCGCCGTCGGTGCTGACAACATCCTGGACGAATACCCGGATGCAGCGCCTCTGGGCCTCAAC
TCGACGGGCAACACGCCCTTCTCGTCCTACTCGCCGTTTGGCTATTCGGGCCGCTTTGTTTACACCAAGGCAACCCTGAA
CTTCTAA

Upstream 100 bases:

>100_bases
CGATTCTTGATCGCGCGGCCCTGCGCACCTTACTTGAAGGTCAGGTTTCTATAGCCACCCGCCGGAGTCCCGGCAAACAC
GCACACGGAGTCATCCTTCA

Downstream 100 bases:

>100_bases
GCGCGAGCCTTCCGCTTACCCACAAACGCCGCCCTTCACGGGGCGGCGTTTTTCTTTGCCTCCACGGCATGCTTGATCTT
GGCGTCACCGCCCCTACTGT

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 828; Mature: 828

Protein sequence:

>828_residues
MKFKVALSAAVAAIALSAVSAPVMAQEQEDEAARTLDTVVTVGTRVANRSALDTAAPVDVVSSEAIQNIGVGELNQSLSV
NLPALNFPRPALTDGTDSVRPAALRGLSPDQTLVLVNGKRRHTASLVNVNGSIGRGASAVDLNTIPNLAVGGVEVLRDGA
SALYGSDAIAGVVNVRLREANTGGAVSVSYGWRETEYTTPVVAPTAAGVPDPGREVTRERSDGHVATVAGWKGFSLGQDG
FLTLTGEYKDQNHTERSGYDFRQQYPGSQPAAEAEIGRFNAWTGEPDLEQISLFANAGYGLANGAELYGWASFQDRETVS
AGFFRRALDDRNTIEIYPNGFLPKINPTTTDYSALGGIRFDFAGWDADASLGYGSNKMEFQIIDTLNRSLGTASGTEFDA
GGFEHSQLVANIGFVKGFAVDGLASDLNVAWGAEARQENYEIFAGEPDSYRNGGVLLPGGGSTASGAQVFPGFQPANELE
EDRTAVGVYLDVEANVTDALLLSGAVRGESYSDFGEALTGKLAARYDFNDAFALRGSIQNGFRAPSLQQQYYTTTSTNFI
NGVPFDVTTFRVDDPIARALGAQDLDAEKSINYAIGAVFQAGAFNMTVDAYRIDVEDRIVLSENLTAGNVQDFLVSQGFI
GSGGGRFFINGVETETTGVDIIANYAFPETEFGSFTATAGANFNKTEVTGVPAIPVLTGLTPPPVLFARTNILTLEEGTP
KDKFTGQVNWEHGPFAGTLRAVRYGEVLVPSNTPALDYTLDPQTLIDLEARYTWNDMLTLAVGADNILDEYPDAAPLGLN
STGNTPFSSYSPFGYSGRFVYTKATLNF

Sequences:

>Translated_828_residues
MKFKVALSAAVAAIALSAVSAPVMAQEQEDEAARTLDTVVTVGTRVANRSALDTAAPVDVVSSEAIQNIGVGELNQSLSV
NLPALNFPRPALTDGTDSVRPAALRGLSPDQTLVLVNGKRRHTASLVNVNGSIGRGASAVDLNTIPNLAVGGVEVLRDGA
SALYGSDAIAGVVNVRLREANTGGAVSVSYGWRETEYTTPVVAPTAAGVPDPGREVTRERSDGHVATVAGWKGFSLGQDG
FLTLTGEYKDQNHTERSGYDFRQQYPGSQPAAEAEIGRFNAWTGEPDLEQISLFANAGYGLANGAELYGWASFQDRETVS
AGFFRRALDDRNTIEIYPNGFLPKINPTTTDYSALGGIRFDFAGWDADASLGYGSNKMEFQIIDTLNRSLGTASGTEFDA
GGFEHSQLVANIGFVKGFAVDGLASDLNVAWGAEARQENYEIFAGEPDSYRNGGVLLPGGGSTASGAQVFPGFQPANELE
EDRTAVGVYLDVEANVTDALLLSGAVRGESYSDFGEALTGKLAARYDFNDAFALRGSIQNGFRAPSLQQQYYTTTSTNFI
NGVPFDVTTFRVDDPIARALGAQDLDAEKSINYAIGAVFQAGAFNMTVDAYRIDVEDRIVLSENLTAGNVQDFLVSQGFI
GSGGGRFFINGVETETTGVDIIANYAFPETEFGSFTATAGANFNKTEVTGVPAIPVLTGLTPPPVLFARTNILTLEEGTP
KDKFTGQVNWEHGPFAGTLRAVRYGEVLVPSNTPALDYTLDPQTLIDLEARYTWNDMLTLAVGADNILDEYPDAAPLGLN
STGNTPFSSYSPFGYSGRFVYTKATLNF
>Mature_828_residues
MKFKVALSAAVAAIALSAVSAPVMAQEQEDEAARTLDTVVTVGTRVANRSALDTAAPVDVVSSEAIQNIGVGELNQSLSV
NLPALNFPRPALTDGTDSVRPAALRGLSPDQTLVLVNGKRRHTASLVNVNGSIGRGASAVDLNTIPNLAVGGVEVLRDGA
SALYGSDAIAGVVNVRLREANTGGAVSVSYGWRETEYTTPVVAPTAAGVPDPGREVTRERSDGHVATVAGWKGFSLGQDG
FLTLTGEYKDQNHTERSGYDFRQQYPGSQPAAEAEIGRFNAWTGEPDLEQISLFANAGYGLANGAELYGWASFQDRETVS
AGFFRRALDDRNTIEIYPNGFLPKINPTTTDYSALGGIRFDFAGWDADASLGYGSNKMEFQIIDTLNRSLGTASGTEFDA
GGFEHSQLVANIGFVKGFAVDGLASDLNVAWGAEARQENYEIFAGEPDSYRNGGVLLPGGGSTASGAQVFPGFQPANELE
EDRTAVGVYLDVEANVTDALLLSGAVRGESYSDFGEALTGKLAARYDFNDAFALRGSIQNGFRAPSLQQQYYTTTSTNFI
NGVPFDVTTFRVDDPIARALGAQDLDAEKSINYAIGAVFQAGAFNMTVDAYRIDVEDRIVLSENLTAGNVQDFLVSQGFI
GSGGGRFFINGVETETTGVDIIANYAFPETEFGSFTATAGANFNKTEVTGVPAIPVLTGLTPPPVLFARTNILTLEEGTP
KDKFTGQVNWEHGPFAGTLRAVRYGEVLVPSNTPALDYTLDPQTLIDLEARYTWNDMLTLAVGADNILDEYPDAAPLGLN
STGNTPFSSYSPFGYSGRFVYTKATLNF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=286, Percent_Identity=27.972027972028, Blast_Score=73, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 87958; Mature: 87958

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKVALSAAVAAIALSAVSAPVMAQEQEDEAARTLDTVVTVGTRVANRSALDTAAPVDV
CEEEEHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
VSSEAIQNIGVGELNQSLSVNLPALNFPRPALTDGTDSVRPAALRGLSPDQTLVLVNGKR
HHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEECCCC
RHTASLVNVNGSIGRGASAVDLNTIPNLAVGGVEVLRDGASALYGSDAIAGVVNVRLREA
CCEEEEEECCCCCCCCCCEEECCCCCCCHHCHHHHHHCCHHHHCCCCCEEEEEEEEEEEC
NTGGAVSVSYGWRETEYTTPVVAPTAAGVPDPGREVTRERSDGHVATVAGWKGFSLGQDG
CCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCCCCCCC
FLTLTGEYKDQNHTERSGYDFRQQYPGSQPAAEAEIGRFNAWTGEPDLEQISLFANAGYG
EEEEEECCCCCCCCCCCCCCHHHHCCCCCCCCHHCCCCEECCCCCCCHHHEEEEECCCCC
LANGAELYGWASFQDRETVSAGFFRRALDDRNTIEIYPNGFLPKINPTTTDYSALGGIRF
CCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHCCEEE
DFAGWDADASLGYGSNKMEFQIIDTLNRSLGTASGTEFDAGGFEHSQLVANIGFVKGFAV
EECCCCCCCCCCCCCCCEEEEEEEHHHHHHCCCCCCCCCCCCCCHHHHHHHCCHHEEEEE
DGLASDLNVAWGAEARQENYEIFAGEPDSYRNGGVLLPGGGSTASGAQVFPGFQPANELE
CCCCCCCCEEECCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCCCCEECCCCCCHHHHH
EDRTAVGVYLDVEANVTDALLLSGAVRGESYSDFGEALTGKLAARYDFNDAFALRGSIQN
CCCEEEEEEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHCCEEEEECCCCEEEEECCCCC
GFRAPSLQQQYYTTTSTNFINGVPFDVTTFRVDDPIARALGAQDLDAEKSINYAIGAVFQ
CCCCCCCCHHEEEECCCCCCCCCCCEEEEEEECCHHHHHCCCCCCCCHHCCCHHEEHEEE
AGAFNMTVDAYRIDVEDRIVLSENLTAGNVQDFLVSQGFIGSGGGRFFINGVETETTGVD
CCCEEEEEEEEEECCCCEEEEECCCCCCCHHHHHHCCCCEECCCCEEEEECCCCCCCCEE
IIANYAFPETEFGSFTATAGANFNKTEVTGVPAIPVLTGLTPPPVLFARTNILTLEEGTP
EEEECCCCCCCCCCEEEECCCCCCCEEECCCCCHHHHCCCCCCCEEEEECEEEEECCCCC
KDKFTGQVNWEHGPFAGTLRAVRYGEVLVPSNTPALDYTLDPQTLIDLEARYTWNDMLTL
CCCCEEEEECCCCCCHHHHHEEEECCEEECCCCCCEEEEECCCEEEEEEEEEEECCEEEE
AVGADNILDEYPDAAPLGLNSTGNTPFSSYSPFGYSGRFVYTKATLNF
EECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MKFKVALSAAVAAIALSAVSAPVMAQEQEDEAARTLDTVVTVGTRVANRSALDTAAPVDV
CEEEEHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
VSSEAIQNIGVGELNQSLSVNLPALNFPRPALTDGTDSVRPAALRGLSPDQTLVLVNGKR
HHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEECCCC
RHTASLVNVNGSIGRGASAVDLNTIPNLAVGGVEVLRDGASALYGSDAIAGVVNVRLREA
CCEEEEEECCCCCCCCCCEEECCCCCCCHHCHHHHHHCCHHHHCCCCCEEEEEEEEEEEC
NTGGAVSVSYGWRETEYTTPVVAPTAAGVPDPGREVTRERSDGHVATVAGWKGFSLGQDG
CCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCCCCCCC
FLTLTGEYKDQNHTERSGYDFRQQYPGSQPAAEAEIGRFNAWTGEPDLEQISLFANAGYG
EEEEEECCCCCCCCCCCCCCHHHHCCCCCCCCHHCCCCEECCCCCCCHHHEEEEECCCCC
LANGAELYGWASFQDRETVSAGFFRRALDDRNTIEIYPNGFLPKINPTTTDYSALGGIRF
CCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHCCEEE
DFAGWDADASLGYGSNKMEFQIIDTLNRSLGTASGTEFDAGGFEHSQLVANIGFVKGFAV
EECCCCCCCCCCCCCCCEEEEEEEHHHHHHCCCCCCCCCCCCCCHHHHHHHCCHHEEEEE
DGLASDLNVAWGAEARQENYEIFAGEPDSYRNGGVLLPGGGSTASGAQVFPGFQPANELE
CCCCCCCCEEECCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCCCCEECCCCCCHHHHH
EDRTAVGVYLDVEANVTDALLLSGAVRGESYSDFGEALTGKLAARYDFNDAFALRGSIQN
CCCEEEEEEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHCCEEEEECCCCEEEEECCCCC
GFRAPSLQQQYYTTTSTNFINGVPFDVTTFRVDDPIARALGAQDLDAEKSINYAIGAVFQ
CCCCCCCCHHEEEECCCCCCCCCCCEEEEEEECCHHHHHCCCCCCCCHHCCCHHEEHEEE
AGAFNMTVDAYRIDVEDRIVLSENLTAGNVQDFLVSQGFIGSGGGRFFINGVETETTGVD
CCCEEEEEEEEEECCCCEEEEECCCCCCCHHHHHHCCCCEECCCCEEEEECCCCCCCCEE
IIANYAFPETEFGSFTATAGANFNKTEVTGVPAIPVLTGLTPPPVLFARTNILTLEEGTP
EEEECCCCCCCCCCEEEECCCCCCCEEECCCCCHHHHCCCCCCCEEEEECEEEEECCCCC
KDKFTGQVNWEHGPFAGTLRAVRYGEVLVPSNTPALDYTLDPQTLIDLEARYTWNDMLTL
CCCCEEEEECCCCCCHHHHHEEEECCEEECCCCCCEEEEECCCEEEEEEEEEEECCEEEE
AVGADNILDEYPDAAPLGLNSTGNTPFSSYSPFGYSGRFVYTKATLNF
EECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]