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The map label for this gene is pabB [H]

Identifier: 114799322

GI number: 114799322

Start: 2466546

End: 2467904

Strand: Reverse

Name: pabB [H]

Synonym: HNE_2369

Alternate gene names: 114799322

Gene position: 2467904-2466546 (Counterclockwise)

Preceding gene: 114800528

Following gene: 114798283

Centisome position: 66.61

GC content: 64.68

Gene sequence:

>1359_bases
ATGCTCGCAGAAGCGCTGCCCTCCTTCGATCCTGTTGCCGCTGCACTGGCTTTGCGGGGGGAGGACGGCTTCCTCTGGCT
CGATAGCGCCGCGCCGGGCCATCCCGGCTCCAGATACTCCTATATCTGCCTCTGGCCGGTGGAACGTCTGCGCCTTGAGG
CATCCGCCGGGGCGGCCCGCGATCTGCGCGCGTGGCGCGCGCGGTTCAGGGCGGAGCGCCTTATACCCGGTGCGCCCTTT
CAGGGGGGCGTTGCAGGCTACCTTTCCTACGATTTTGCGCCCGCCTTCATGGGCCGTTTCAAGTCCCGTCACACGCCGGT
TGACACGCCGGCGCTGGAGTTTGGCTTCTACGACACGGTGATCGCCTTCAATCACGCCGCCCAAATTGCCACGATCTATT
CTGCGGGGCTGAAGACCGGCGATACTGCGGCGGATGAAACCCTCGCAAAGGAGAAAATCAGCCGCCTGAAAGCAAAACTG
GCGGAGACCGCCCCGCCTGCACCGCCGCCCGAAAAGCTCGCCTGGACCGCGGAAAACTCTGCCACCGCCTACAAAGTCTC
CGTCTTCCGCATCCGCGACTATATCCGCGACGGCGACATCTATCAGGCAAACGTGGCGGCCCTCTGGACCGCTCCGCCGC
TCAACCGGGACGCCGCCTTCGCGCAATATCTTTCCGGCCGGGCCCGTTCCCCCGCGCCGTTTTCAGCCTTCGGCGTATTT
GAGGGCCGCACCATCGCCAGTTTTTCCCCCGAACGCCTGATCAGCGCTGACGGGGAAGGATGCGTGAAGGCCGAGCCCAT
CAAAGGCACGATCCGGCGCGAGGAAGACGAGACCAAAGACGCCGCTGCCCGCGCGGCGCTGCTCGCCTCGGATAAGGACC
GGGCGGAGAATGTGATGATCGTCGACCTCCTGCGAAATGACATTTCGCGGGTCTGCACATCGCCGTCCGTGTCTGTCTCC
TCGCTCTGCCGGCTGGAGACCTTCGCCAATCTGCACCACCTCGTCTCGACGGTGGAGGGGCAACTGGCGCCTGGAGAAGA
CGGGGTAAGCCTGCTGGAAGCCGTCTTCCCCGGCGGGTCGATCACCGGCGCGCCCAAGCTGCGCGCGATGGAGATCATCG
ACGCGCTGGAGCCTGCCGCGCGGGGCGTTTTCTGCGGCTCAATCGGGTGGATCGGCCATGACGGCGCGATGGATTTTTCC
ATCCTGATCCGAACCGTGGAAGCGTTGCCGGAGGTGACACGGCTATGGGCCGGCGCAGGCATCACGCTTCTGTCTGATCC
GGAGGCGGAGTATGACGAAATCAGCCTGAAAGCCGAACGCATCATGGGCGATACACGCGGTGGGGTGGCCACGTCATGA

Upstream 100 bases:

>100_bases
GCCGACCGGGGCGAAATGTCCCGTGTTTGCAGCGCTCTGGCACGCTCCGAAGCCGTGCTTGCGCCTTTCCGCAATACCGC
TTGCGGGCTAGAGAAAGCCC

Downstream 100 bases:

>100_bases
TCCTGATGCTGAACAACCGGGACAGTTTCGTATTCAATCTTGCCCGCTATTTCAGCGAGCTGGGCTGTGAGATGAATGTG
GTAGACAGTGATCAGATCGC

Product: 4-amino-4-deoxychorismate synthase, aminodeoxychorismate synthase subunit

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MLAEALPSFDPVAAALALRGEDGFLWLDSAAPGHPGSRYSYICLWPVERLRLEASAGAARDLRAWRARFRAERLIPGAPF
QGGVAGYLSYDFAPAFMGRFKSRHTPVDTPALEFGFYDTVIAFNHAAQIATIYSAGLKTGDTAADETLAKEKISRLKAKL
AETAPPAPPPEKLAWTAENSATAYKVSVFRIRDYIRDGDIYQANVAALWTAPPLNRDAAFAQYLSGRARSPAPFSAFGVF
EGRTIASFSPERLISADGEGCVKAEPIKGTIRREEDETKDAAARAALLASDKDRAENVMIVDLLRNDISRVCTSPSVSVS
SLCRLETFANLHHLVSTVEGQLAPGEDGVSLLEAVFPGGSITGAPKLRAMEIIDALEPAARGVFCGSIGWIGHDGAMDFS
ILIRTVEALPEVTRLWAGAGITLLSDPEAEYDEISLKAERIMGDTRGGVATS

Sequences:

>Translated_452_residues
MLAEALPSFDPVAAALALRGEDGFLWLDSAAPGHPGSRYSYICLWPVERLRLEASAGAARDLRAWRARFRAERLIPGAPF
QGGVAGYLSYDFAPAFMGRFKSRHTPVDTPALEFGFYDTVIAFNHAAQIATIYSAGLKTGDTAADETLAKEKISRLKAKL
AETAPPAPPPEKLAWTAENSATAYKVSVFRIRDYIRDGDIYQANVAALWTAPPLNRDAAFAQYLSGRARSPAPFSAFGVF
EGRTIASFSPERLISADGEGCVKAEPIKGTIRREEDETKDAAARAALLASDKDRAENVMIVDLLRNDISRVCTSPSVSVS
SLCRLETFANLHHLVSTVEGQLAPGEDGVSLLEAVFPGGSITGAPKLRAMEIIDALEPAARGVFCGSIGWIGHDGAMDFS
ILIRTVEALPEVTRLWAGAGITLLSDPEAEYDEISLKAERIMGDTRGGVATS
>Mature_452_residues
MLAEALPSFDPVAAALALRGEDGFLWLDSAAPGHPGSRYSYICLWPVERLRLEASAGAARDLRAWRARFRAERLIPGAPF
QGGVAGYLSYDFAPAFMGRFKSRHTPVDTPALEFGFYDTVIAFNHAAQIATIYSAGLKTGDTAADETLAKEKISRLKAKL
AETAPPAPPPEKLAWTAENSATAYKVSVFRIRDYIRDGDIYQANVAALWTAPPLNRDAAFAQYLSGRARSPAPFSAFGVF
EGRTIASFSPERLISADGEGCVKAEPIKGTIRREEDETKDAAARAALLASDKDRAENVMIVDLLRNDISRVCTSPSVSVS
SLCRLETFANLHHLVSTVEGQLAPGEDGVSLLEAVFPGGSITGAPKLRAMEIIDALEPAARGVFCGSIGWIGHDGAMDFS
ILIRTVEALPEVTRLWAGAGITLLSDPEAEYDEISLKAERIMGDTRGGVATS

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=364, Percent_Identity=37.6373626373626, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI1787518, Length=375, Percent_Identity=27.4666666666667, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786809, Length=203, Percent_Identity=31.5270935960591, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87082077, Length=206, Percent_Identity=27.1844660194175, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320935, Length=464, Percent_Identity=33.6206896551724, Blast_Score=202, Evalue=9e-53,
Organism=Saccharomyces cerevisiae, GI6324361, Length=412, Percent_Identity=26.9417475728155, Blast_Score=118, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 48520; Mature: 48520

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAEALPSFDPVAAALALRGEDGFLWLDSAAPGHPGSRYSYICLWPVERLRLEASAGAAR
CCCCCCCCCCHHHHHHEEECCCCEEEECCCCCCCCCCCEEEEEECCHHHHEEECCCCCHH
DLRAWRARFRAERLIPGAPFQGGVAGYLSYDFAPAFMGRFKSRHTPVDTPALEFGFYDTV
HHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCHHHH
IAFNHAAQIATIYSAGLKTGDTAADETLAKEKISRLKAKLAETAPPAPPPEKLAWTAENS
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEECCCC
ATAYKVSVFRIRDYIRDGDIYQANVAALWTAPPLNRDAAFAQYLSGRARSPAPFSAFGVF
CCEEEEEHHHHHHHHHCCCEEEECEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCEEECC
EGRTIASFSPERLISADGEGCVKAEPIKGTIRREEDETKDAAARAALLASDKDRAENVMI
CCCEEECCCHHHHHCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHCCEEE
VDLLRNDISRVCTSPSVSVSSLCRLETFANLHHLVSTVEGQLAPGEDGVSLLEAVFPGGS
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
ITGAPKLRAMEIIDALEPAARGVFCGSIGWIGHDGAMDFSILIRTVEALPEVTRLWAGAG
CCCCCCHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
ITLLSDPEAEYDEISLKAERIMGDTRGGVATS
EEEECCCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLAEALPSFDPVAAALALRGEDGFLWLDSAAPGHPGSRYSYICLWPVERLRLEASAGAAR
CCCCCCCCCCHHHHHHEEECCCCEEEECCCCCCCCCCCEEEEEECCHHHHEEECCCCCHH
DLRAWRARFRAERLIPGAPFQGGVAGYLSYDFAPAFMGRFKSRHTPVDTPALEFGFYDTV
HHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCHHHH
IAFNHAAQIATIYSAGLKTGDTAADETLAKEKISRLKAKLAETAPPAPPPEKLAWTAENS
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEECCCC
ATAYKVSVFRIRDYIRDGDIYQANVAALWTAPPLNRDAAFAQYLSGRARSPAPFSAFGVF
CCEEEEEHHHHHHHHHCCCEEEECEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCEEECC
EGRTIASFSPERLISADGEGCVKAEPIKGTIRREEDETKDAAARAALLASDKDRAENVMI
CCCEEECCCHHHHHCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHCCEEE
VDLLRNDISRVCTSPSVSVSSLCRLETFANLHHLVSTVEGQLAPGEDGVSLLEAVFPGGS
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
ITGAPKLRAMEIIDALEPAARGVFCGSIGWIGHDGAMDFSILIRTVEALPEVTRLWAGAG
CCCCCCHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
ITLLSDPEAEYDEISLKAERIMGDTRGGVATS
EEEECCCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]