BacMap

Definition	Hyphomonas neptunium ATCC 15444 chromosome, complete genome.
Accession	NC_008358
Length	3,705,021

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The map label for this gene is hmuV [H]

Identifier: 114797990

GI number: 114797990

Start: 1552058

End: 1552819

Strand: Direct

Name: hmuV [H]

Synonym: HNE_1517

Alternate gene names: 114797990

Gene position: 1552058-1552819 (Clockwise)

Preceding gene: 114797228

Following gene: 114797305

Centisome position: 41.89

GC content: 62.6

Gene sequence:

>762_bases
ATGGCTGACCTTGTGATCCGCAACCTTTCTGTGAGCGCTGGCAAGGTCAAACTTGTTTGCGAGGCGAATTTCAGTCTGGC
GCAGGGCGAACTGGTGGCACTGCTGGGCCCTAACGGAGCCGGGAAAACCAGCCTACTTCGCTCAGCACTCGGGCTTGTAA
AGCGGGCCACTGGCGATGCGTTGCTGGATGGTACTGACAGCGAAAAGCTCTCGTCCATGCAGCGCGCTCGCCGGGTCGCC
TATCTGCCGCAACAGCGCCCGCTCGCCTGGCCGAACACAGTCCGCGACGTTGTCGCCCTTGGCCGCTTTGCCTACGGCGC
TGCTCCGGGGCGCCTGAGCCAGGCTGATTCTGTTGCCGTTGAGCGCGCCATCAGGCTCTGCGACCTTACCGCTCTCGTCG
ACCGTCATACCGACACGCTATCGGGCGGTGAACTTGCGCGAGTTCATTGTGCCCGGGCCTTCGCGGCAGACGCCCCGCTT
CTGGTCGCGGATGAGCCTGTGGCCGCGCTGGATCCGCGCCATCAATACCGCGTCATGGATATCATCCGCCACTACGTCGA
CGGGGGAGGTGGCGCGCTCGTCGTCCTTCACGACATCGCCCTTGCTGCACGATATGCAACACGGATGGTCTGGATGAAGC
ACGGGCACATCATAGCCGATGGCACACCCGATGAGACGCTTACGGAGGATCGTCTGGCTGAAGTCTACGGGGTCCGCGCG
CGTGTGAGTGGCCGCTCCGTAGAGATAGAAGGGACAATATGA

Upstream 100 bases:

>100_bases
CGCCTGCTGCCGACCTCCAACGAGCTTAAACTGGGCGTCGTCGCTTCGTTGGTCGGCGCTCCTGCCTTTGTCTGGATCGC
AATGAGAAGGCGTACCCTGA

Downstream 100 bases:

>100_bases
CAGCAAAGATATTGATGCTGCAGGGCACAGGTTCTGATGTCGGAAAGTCCATACTTTCGGCAGCGATTTGCCGGATTGCA
AAACGCCGGGGCTTGAACGT

Product: iron compound ABC transporter ATP-binding protein

Products: ADP; phosphate; iron (III) hydroxamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MADLVIRNLSVSAGKVKLVCEANFSLAQGELVALLGPNGAGKTSLLRSALGLVKRATGDALLDGTDSEKLSSMQRARRVA
YLPQQRPLAWPNTVRDVVALGRFAYGAAPGRLSQADSVAVERAIRLCDLTALVDRHTDTLSGGELARVHCARAFAADAPL
LVADEPVAALDPRHQYRVMDIIRHYVDGGGGALVVLHDIALAARYATRMVWMKHGHIIADGTPDETLTEDRLAEVYGVRA
RVSGRSVEIEGTI

Sequences:

>Translated_253_residues
MADLVIRNLSVSAGKVKLVCEANFSLAQGELVALLGPNGAGKTSLLRSALGLVKRATGDALLDGTDSEKLSSMQRARRVA
YLPQQRPLAWPNTVRDVVALGRFAYGAAPGRLSQADSVAVERAIRLCDLTALVDRHTDTLSGGELARVHCARAFAADAPL
LVADEPVAALDPRHQYRVMDIIRHYVDGGGGALVVLHDIALAARYATRMVWMKHGHIIADGTPDETLTEDRLAEVYGVRA
RVSGRSVEIEGTI
>Mature_252_residues
ADLVIRNLSVSAGKVKLVCEANFSLAQGELVALLGPNGAGKTSLLRSALGLVKRATGDALLDGTDSEKLSSMQRARRVAY
LPQQRPLAWPNTVRDVVALGRFAYGAAPGRLSQADSVAVERAIRLCDLTALVDRHTDTLSGGELARVHCARAFAADAPLL
VADEPVAALDPRHQYRVMDIIRHYVDGGGGALVVLHDIALAARYATRMVWMKHGHIIADGTPDETLTEDRLAEVYGVRAR
VSGRSVEIEGTI

Specific function: Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system [H]

COG id: COG1120

COG function: function code PH; ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI157502203, Length=213, Percent_Identity=30.5164319248826, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI157502201, Length=213, Percent_Identity=30.5164319248826, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI153792144, Length=185, Percent_Identity=30.2702702702703, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI31657092, Length=211, Percent_Identity=27.4881516587678, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI27436953, Length=203, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI105990541, Length=202, Percent_Identity=26.2376237623762, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI27477115, Length=204, Percent_Identity=28.4313725490196, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI27262624, Length=212, Percent_Identity=25.9433962264151, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI27262626, Length=212, Percent_Identity=25.9433962264151, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI116734710, Length=247, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI6005701, Length=202, Percent_Identity=27.7227722772277, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI171184400, Length=229, Percent_Identity=25.3275109170306, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI45446740, Length=221, Percent_Identity=25.7918552036199, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1786345, Length=236, Percent_Identity=39.4067796610169, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1790739, Length=245, Percent_Identity=35.9183673469388, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1786803, Length=237, Percent_Identity=32.0675105485232, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1789593, Length=239, Percent_Identity=34.3096234309623, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787029, Length=224, Percent_Identity=29.9107142857143, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788761, Length=225, Percent_Identity=32, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790544, Length=233, Percent_Identity=33.9055793991416, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87081709, Length=221, Percent_Identity=30.7692307692308, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787089, Length=205, Percent_Identity=34.1463414634146, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788165, Length=246, Percent_Identity=31.3008130081301, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI87081791, Length=227, Percent_Identity=30.3964757709251, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790162, Length=257, Percent_Identity=26.8482490272374, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789672, Length=232, Percent_Identity=25.4310344827586, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1789032, Length=216, Percent_Identity=30.0925925925926, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786253, Length=209, Percent_Identity=33.9712918660287, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786872, Length=239, Percent_Identity=28.4518828451883, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788450, Length=233, Percent_Identity=28.755364806867, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787370, Length=254, Percent_Identity=28.740157480315, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1789891, Length=218, Percent_Identity=33.4862385321101, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87081782, Length=219, Percent_Identity=28.7671232876712, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI87081834, Length=203, Percent_Identity=31.0344827586207, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786563, Length=215, Percent_Identity=33.0232558139535, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788002, Length=233, Percent_Identity=30.9012875536481, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788225, Length=233, Percent_Identity=28.3261802575107, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87082268, Length=234, Percent_Identity=27.3504273504274, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790467, Length=228, Percent_Identity=28.0701754385965, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082267, Length=228, Percent_Identity=27.6315789473684, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787500, Length=207, Percent_Identity=28.5024154589372, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789873, Length=200, Percent_Identity=29, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787792, Length=211, Percent_Identity=27.0142180094787, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1786698, Length=197, Percent_Identity=28.9340101522843, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1789890, Length=229, Percent_Identity=28.3842794759825, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789864, Length=235, Percent_Identity=26.8085106382979, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788472, Length=220, Percent_Identity=24.5454545454545, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787112, Length=204, Percent_Identity=29.4117647058824, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790190, Length=232, Percent_Identity=26.2931034482759, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693107, Length=217, Percent_Identity=29.0322580645161, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786319, Length=192, Percent_Identity=26.0416666666667, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786398, Length=212, Percent_Identity=28.3018867924528, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789963, Length=239, Percent_Identity=28.8702928870293, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786653, Length=215, Percent_Identity=28.3720930232558, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI48994997, Length=238, Percent_Identity=26.890756302521, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1787759, Length=239, Percent_Identity=27.1966527196653, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787105, Length=244, Percent_Identity=28.2786885245902, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788644, Length=86, Percent_Identity=34.8837209302326, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787712, Length=232, Percent_Identity=26.7241379310345, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788053, Length=177, Percent_Identity=28.2485875706215, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787164, Length=208, Percent_Identity=30.2884615384615, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1789991, Length=230, Percent_Identity=24.7826086956522, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1790525, Length=239, Percent_Identity=23.8493723849372, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI1788506, Length=244, Percent_Identity=28.2786885245902, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1788210, Length=257, Percent_Identity=24.5136186770428, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI115534520, Length=239, Percent_Identity=26.3598326359833, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115533608, Length=217, Percent_Identity=25.3456221198157, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193211015, Length=213, Percent_Identity=24.8826291079812, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71996809, Length=213, Percent_Identity=24.8826291079812, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193211017, Length=213, Percent_Identity=24.8826291079812, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71983523, Length=235, Percent_Identity=25.1063829787234, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71983516, Length=235, Percent_Identity=25.1063829787234, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71983510, Length=235, Percent_Identity=25.1063829787234, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17510237, Length=222, Percent_Identity=25.2252252252252, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17565938, Length=213, Percent_Identity=24.8826291079812, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193209708, Length=217, Percent_Identity=29.0322580645161, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=219, Percent_Identity=23.7442922374429, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71988343, Length=251, Percent_Identity=24.7011952191235, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17567265, Length=225, Percent_Identity=24, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323217, Length=234, Percent_Identity=25.2136752136752, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322640, Length=248, Percent_Identity=26.2096774193548, Blast_Score=65, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320296, Length=210, Percent_Identity=27.6190476190476, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320339, Length=213, Percent_Identity=29.5774647887324, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650855, Length=206, Percent_Identity=25.2427184466019, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24650853, Length=206, Percent_Identity=25.2427184466019, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI281362751, Length=232, Percent_Identity=25, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24582014, Length=209, Percent_Identity=23.9234449760766, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582012, Length=209, Percent_Identity=23.9234449760766, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24666092, Length=223, Percent_Identity=26.0089686098655, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17136592, Length=243, Percent_Identity=27.9835390946502, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI85726357, Length=217, Percent_Identity=26.2672811059908, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24659289, Length=213, Percent_Identity=25.8215962441315, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161076682, Length=171, Percent_Identity=26.9005847953216, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI161076684, Length=171, Percent_Identity=26.9005847953216, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24581617, Length=171, Percent_Identity=26.9005847953216, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24581615, Length=171, Percent_Identity=26.9005847953216, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR015863
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27080; Mature: 26949

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLVIRNLSVSAGKVKLVCEANFSLAQGELVALLGPNGAGKTSLLRSALGLVKRATGDA
CCCEEEECCCCCCCEEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCE
LLDGTDSEKLSSMQRARRVAYLPQQRPLAWPNTVRDVVALGRFAYGAAPGRLSQADSVAV
EECCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ERAIRLCDLTALVDRHTDTLSGGELARVHCARAFAADAPLLVADEPVAALDPRHQYRVMD
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCHHHCCCCHHHHHHH
IIRHYVDGGGGALVVLHDIALAARYATRMVWMKHGHIIADGTPDETLTEDRLAEVYGVRA
HHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHEECCEEEECCCCCCHHHHHHHHHHHHHHE
RVSGRSVEIEGTI
EECCCEEEEEECC
>Mature Secondary Structure 
ADLVIRNLSVSAGKVKLVCEANFSLAQGELVALLGPNGAGKTSLLRSALGLVKRATGDA
CCEEEECCCCCCCEEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCE
LLDGTDSEKLSSMQRARRVAYLPQQRPLAWPNTVRDVVALGRFAYGAAPGRLSQADSVAV
EECCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ERAIRLCDLTALVDRHTDTLSGGELARVHCARAFAADAPLLVADEPVAALDPRHQYRVMD
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCHHHCCCCHHHHHHH
IIRHYVDGGGGALVVLHDIALAARYATRMVWMKHGHIIADGTPDETLTEDRLAEVYGVRA
HHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHEECCEEEECCCCCCHHHHHHHHHHHHHHE
RVSGRSVEIEGTI
EECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron (III) hydroxamate [Periplasm]; H2O [C]

Specific reaction: ATP + iron (III) hydroxamate [Periplasm] + H2O = ADP + phosphate + iron (III) hydroxamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11292789 [H]