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The map label for this gene is 114797367

Identifier: 114797367

GI number: 114797367

Start: 1110187

End: 1111500

Strand: Direct

Name: 114797367

Synonym: HNE_1104

Alternate gene names: NA

Gene position: 1110187-1111500 (Clockwise)

Preceding gene: 114799908

Following gene: 114797886

Centisome position: 29.96

GC content: 67.28

Gene sequence:

>1314_bases
ATGCCCGAGGCGGCGCAAGGGGCGGTGAAGACGTTCCTGCTCGACAGTCTCGGGGTCGGCATTGCCGGTGCGGGCGCGCC
GCTGACGGCGAATGTGCGCCAGGCGGCGCTGGCCTGGGCCGGGGCGGGCGACGCGAATGTCTGGGGACAGGGCAGCTACC
GGACGAGCGCAGCGAATGCGGCGTTCATCAATGGCTTCCAGATCCACTGCCAGGAATTTGACTGTGTCCATGAGCCGGCC
GTGGTTCATCCCATGGCGACGATCCTCGCAGCCCTGATGGCGACTTGCGACCGGGAACGCGGCGTGACCGGCACGGAACT
GGGCGCGGCGATTGCGGCGGCGGTAGATGTAGCAACCGGCCTTGGCGTTGCGGCGCAGACACCGCTGAAATTTTTCCGGC
CGGCGACGGCGGGCATATTCGGCGCAACGCTGGGCGTGGCGCGGCTTCGAGGGCTGAGCGAGAGCGAGGCGCGCAATGCG
CTGGGCTATGCGCTCTCCTTTGCGGCGGGCACGATGCAGGCGCACACCGAGGGCAAGCCGGCGCTGCCGGTGCAGATTGC
CAATGCGGCCCGCAGCGCCGTGATGGCGTGTGACCTGGCCGCCGCTGGAATGGAGGCGGCTCAGGACAGTCTCGAAGGGC
CGTTCGGATACCTCGCGCTGTTTGAGGATGGTTTCGATGTAGCGCCGGTGGTGGCCTCACTGGGAACCGTGTTCCGGATT
GCAGAGGTGAGCCACAAGCCGTTCCCAACCGGACGCGCGGCGCAGGGGGGCATTGTGCTGGCCAAACAGGCGAAGGCTGC
GGGCATCCGGCCTGAAGAGATTTCGTCTATCACGCTGACGGCGCCGCCGATCATCAAGCGGCTGGTCGGGCGCCCGGCGC
AGGCAGGCATGACGGCGAGTTATGCGCGGCTCTGCTACCAGTATTCGGGCGCGCTGACGCTGATCGACGGGCATGTGGGC
CTCAAGGACTTCACGCCCGAGGCGCTGGCGCGGGCCGATGTGGCGGCGCTGGGCGCAAAGATTGCGGTGATCGATGACGG
GCAGACAAACCCGGCGGCCTTCACGCCGCAGGTTCTGCGCGTGGAGCTGACCTCCGGAGCGGCGCGCGAATTTTCCATCG
AGTCCCTTCTGGGCGCCCCCGCGAACCCGCTGAGCGCGGCGCAGAATGAAGCGAAGTTCCGGGAGTGCTGTGCGTTCGGC
TTCGGGCGCGGGCGCGAAGACATTGAAGCGGCGATGAGCGCCGCTGTAGCCGATCTTGAAAACCTTGAGGATGCCGGGCG
GCTTTCCCGCCTTGCGTCTGGTATAATGGAGTGA

Upstream 100 bases:

>100_bases
CGGCCTCGCCCGAACTGGGCGGTCTGATCCTCAAGGTGCTGGCATGAGCGGAGCGGCGGAAGCCTTTGTGCGCCATACCC
TCACCCTCCGCTGGGAGGCG

Downstream 100 bases:

>100_bases
TCCGATGACGGATGGACATAACACATACTTCAATACGGTCGACTGGGCAAAGATGCAGGAAGAACATCCCGTAGGGGACG
CGTTCCTGACATTTGCCAAA

Product: MmgE/PrpD family protein

Products: NA

Alternate protein names: MmgE/PrpD; MmgE/PrpD Family; Protein Involved In Propionate Catabolism; 2-Methylcitrate Dehydratase; Catabolic; MmgE/PrpD Family Superfamily; MmgE/Prp Family Protein

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MPEAAQGAVKTFLLDSLGVGIAGAGAPLTANVRQAALAWAGAGDANVWGQGSYRTSAANAAFINGFQIHCQEFDCVHEPA
VVHPMATILAALMATCDRERGVTGTELGAAIAAAVDVATGLGVAAQTPLKFFRPATAGIFGATLGVARLRGLSESEARNA
LGYALSFAAGTMQAHTEGKPALPVQIANAARSAVMACDLAAAGMEAAQDSLEGPFGYLALFEDGFDVAPVVASLGTVFRI
AEVSHKPFPTGRAAQGGIVLAKQAKAAGIRPEEISSITLTAPPIIKRLVGRPAQAGMTASYARLCYQYSGALTLIDGHVG
LKDFTPEALARADVAALGAKIAVIDDGQTNPAAFTPQVLRVELTSGAAREFSIESLLGAPANPLSAAQNEAKFRECCAFG
FGRGREDIEAAMSAAVADLENLEDAGRLSRLASGIME

Sequences:

>Translated_437_residues
MPEAAQGAVKTFLLDSLGVGIAGAGAPLTANVRQAALAWAGAGDANVWGQGSYRTSAANAAFINGFQIHCQEFDCVHEPA
VVHPMATILAALMATCDRERGVTGTELGAAIAAAVDVATGLGVAAQTPLKFFRPATAGIFGATLGVARLRGLSESEARNA
LGYALSFAAGTMQAHTEGKPALPVQIANAARSAVMACDLAAAGMEAAQDSLEGPFGYLALFEDGFDVAPVVASLGTVFRI
AEVSHKPFPTGRAAQGGIVLAKQAKAAGIRPEEISSITLTAPPIIKRLVGRPAQAGMTASYARLCYQYSGALTLIDGHVG
LKDFTPEALARADVAALGAKIAVIDDGQTNPAAFTPQVLRVELTSGAAREFSIESLLGAPANPLSAAQNEAKFRECCAFG
FGRGREDIEAAMSAAVADLENLEDAGRLSRLASGIME
>Mature_436_residues
PEAAQGAVKTFLLDSLGVGIAGAGAPLTANVRQAALAWAGAGDANVWGQGSYRTSAANAAFINGFQIHCQEFDCVHEPAV
VHPMATILAALMATCDRERGVTGTELGAAIAAAVDVATGLGVAAQTPLKFFRPATAGIFGATLGVARLRGLSESEARNAL
GYALSFAAGTMQAHTEGKPALPVQIANAARSAVMACDLAAAGMEAAQDSLEGPFGYLALFEDGFDVAPVVASLGTVFRIA
EVSHKPFPTGRAAQGGIVLAKQAKAAGIRPEEISSITLTAPPIIKRLVGRPAQAGMTASYARLCYQYSGALTLIDGHVGL
KDFTPEALARADVAALGAKIAVIDDGQTNPAAFTPQVLRVELTSGAAREFSIESLLGAPANPLSAAQNEAKFRECCAFGF
GRGREDIEAAMSAAVADLENLEDAGRLSRLASGIME

Specific function: Unknown

COG id: COG2079

COG function: function code R; Uncharacterized protein involved in propionate catabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI310129732, Length=442, Percent_Identity=27.6018099547511, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI310110533, Length=442, Percent_Identity=27.6018099547511, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI310123058, Length=442, Percent_Identity=27.6018099547511, Blast_Score=121, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 44723; Mature: 44592

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEAAQGAVKTFLLDSLGVGIAGAGAPLTANVRQAALAWAGAGDANVWGQGSYRTSAANA
CCCHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCH
AFINGFQIHCQEFDCVHEPAVVHPMATILAALMATCDRERGVTGTELGAAIAAAVDVATG
HEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
LGVAAQTPLKFFRPATAGIFGATLGVARLRGLSESEARNALGYALSFAAGTMQAHTEGKP
CCCHHCCCHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHECCCCCCC
ALPVQIANAARSAVMACDLAAAGMEAAQDSLEGPFGYLALFEDGFDVAPVVASLGTVFRI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHH
AEVSHKPFPTGRAAQGGIVLAKQAKAAGIRPEEISSITLTAPPIIKRLVGRPAQAGMTAS
HHHCCCCCCCCCCCCCCEEEEECHHHCCCCHHHCCEEEECCCHHHHHHHCCCCCCCCHHH
YARLCYQYSGALTLIDGHVGLKDFTPEALARADVAALGAKIAVIDDGQTNPAAFTPQVLR
HHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEE
VELTSGAAREFSIESLLGAPANPLSAAQNEAKFRECCAFGFGRGREDIEAAMSAAVADLE
EEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
NLEDAGRLSRLASGIME
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PEAAQGAVKTFLLDSLGVGIAGAGAPLTANVRQAALAWAGAGDANVWGQGSYRTSAANA
CCHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCH
AFINGFQIHCQEFDCVHEPAVVHPMATILAALMATCDRERGVTGTELGAAIAAAVDVATG
HEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
LGVAAQTPLKFFRPATAGIFGATLGVARLRGLSESEARNALGYALSFAAGTMQAHTEGKP
CCCHHCCCHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHECCCCCCC
ALPVQIANAARSAVMACDLAAAGMEAAQDSLEGPFGYLALFEDGFDVAPVVASLGTVFRI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHH
AEVSHKPFPTGRAAQGGIVLAKQAKAAGIRPEEISSITLTAPPIIKRLVGRPAQAGMTAS
HHHCCCCCCCCCCCCCCEEEEECHHHCCCCHHHCCEEEECCCHHHHHHHCCCCCCCCHHH
YARLCYQYSGALTLIDGHVGLKDFTPEALARADVAALGAKIAVIDDGQTNPAAFTPQVLR
HHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEE
VELTSGAAREFSIESLLGAPANPLSAAQNEAKFRECCAFGFGRGREDIEAAMSAAVADLE
EEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
NLEDAGRLSRLASGIME
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA