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The map label for this gene is yaaD [H]

Identifier: 114797691

GI number: 114797691

Start: 916005

End: 916442

Strand: Direct

Name: yaaD [H]

Synonym: HNE_0897

Alternate gene names: 114797691

Gene position: 916005-916442 (Clockwise)

Preceding gene: 114797056

Following gene: 114800043

Centisome position: 24.72

GC content: 63.24

Gene sequence:

>438_bases
ATGACCCAGGTCAAACAAGGCGACACCGTACACATCCACTATACCGGCACCCTGAAAGACGGCACGACATTCGACAGCTC
GCAGGGCCGCGACCCGCTGGCGTTTGAAGTCGGCACCGGCCAGATCATTCCCGGCCTGGACGCCGCCATTCCCGGCATGG
CCGTCGGCGACAAGAAAACCGTCACCGTCCCCTGCGAAGAAGCTTACGGCCCGATGAACCCCGACATGCGCCAGGATGTT
CCACGCGCCGATATTCCCGCTGAAGTTCCTGTCGAGGTCGGCACCCGCCTTCAGATGCAGACGCAGTCCGGCCAGCCCGT
CCCGGTCGTCGTCGTCGCCTCCGACGACAAGACCGTCACCCTGGACGCCAATCACCCGCTCGCCGGTCAGGACCTGACGT
TCGACATTGAACTGGTGGCGATCAAAGAAGCGGCGTAA

Upstream 100 bases:

>100_bases
TTGTGGCCGAGCCCTATCCTTTAGGCGACGAGAGCCCCTTGGCGCGCGCGTGATGTGCGTGCCGTTCGATTCCCCAACCT
CCGAAATGATTGGAATTCCC

Downstream 100 bases:

>100_bases
CGAGACCGAATGAAAGCTGGGCTGATTTTCAGCCCAGCTTCTCCGCCGCGCGTTCCGCAAAATACGTGATTACGCCAGCT
GCGCCCGCGCGCTTGAAGCT

Product: FKBP-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MTQVKQGDTVHIHYTGTLKDGTTFDSSQGRDPLAFEVGTGQIIPGLDAAIPGMAVGDKKTVTVPCEEAYGPMNPDMRQDV
PRADIPAEVPVEVGTRLQMQTQSGQPVPVVVVASDDKTVTLDANHPLAGQDLTFDIELVAIKEAA

Sequences:

>Translated_145_residues
MTQVKQGDTVHIHYTGTLKDGTTFDSSQGRDPLAFEVGTGQIIPGLDAAIPGMAVGDKKTVTVPCEEAYGPMNPDMRQDV
PRADIPAEVPVEVGTRLQMQTQSGQPVPVVVVASDDKTVTLDANHPLAGQDLTFDIELVAIKEAA
>Mature_144_residues
TQVKQGDTVHIHYTGTLKDGTTFDSSQGRDPLAFEVGTGQIIPGLDAAIPGMAVGDKKTVTVPCEEAYGPMNPDMRQDVP
RADIPAEVPVEVGTRLQMQTQSGQPVPVVVVASDDKTVTLDANHPLAGQDLTFDIELVAIKEAA

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI7706131, Length=64, Percent_Identity=51.5625, Blast_Score=77, Evalue=5e-15,
Organism=Homo sapiens, GI219842220, Length=64, Percent_Identity=51.5625, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI206725530, Length=67, Percent_Identity=47.7611940298507, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI17149844, Length=67, Percent_Identity=47.7611940298507, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI17149842, Length=67, Percent_Identity=47.7611940298507, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI4503727, Length=99, Percent_Identity=39.3939393939394, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1789748, Length=136, Percent_Identity=39.7058823529412, Blast_Score=93, Evalue=6e-21,
Organism=Escherichia coli, GI1786211, Length=143, Percent_Identity=32.8671328671329, Blast_Score=82, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17540882, Length=67, Percent_Identity=44.7761194029851, Blast_Score=70, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17561778, Length=69, Percent_Identity=46.3768115942029, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6320727, Length=91, Percent_Identity=41.7582417582418, Blast_Score=72, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324194, Length=68, Percent_Identity=51.4705882352941, Blast_Score=71, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323566, Length=85, Percent_Identity=36.4705882352941, Blast_Score=65, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323482, Length=85, Percent_Identity=35.2941176470588, Blast_Score=63, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281363946, Length=68, Percent_Identity=48.5294117647059, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17352457, Length=68, Percent_Identity=48.5294117647059, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356629, Length=65, Percent_Identity=47.6923076923077, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 15352; Mature: 15221

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQVKQGDTVHIHYTGTLKDGTTFDSSQGRDPLAFEVGTGQIIPGLDAAIPGMAVGDKKT
CCCCCCCCEEEEEEEEEECCCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCEE
VTVPCEEAYGPMNPDMRQDVPRADIPAEVPVEVGTRLQMQTQSGQPVPVVVVASDDKTVT
EEEEHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCEEE
LDANHPLAGQDLTFDIELVAIKEAA
EECCCCCCCCCEEEEEEEEEEEECC
>Mature Secondary Structure 
TQVKQGDTVHIHYTGTLKDGTTFDSSQGRDPLAFEVGTGQIIPGLDAAIPGMAVGDKKT
CCCCCCCEEEEEEEEEECCCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCEE
VTVPCEEAYGPMNPDMRQDVPRADIPAEVPVEVGTRLQMQTQSGQPVPVVVVASDDKTVT
EEEEHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCEEE
LDANHPLAGQDLTFDIELVAIKEAA
EECCCCCCCCCEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2121716 [H]