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The map label for this gene is pntAB [H]

Identifier: 114799782

GI number: 114799782

Start: 1150739

End: 1151110

Strand: Reverse

Name: pntAB [H]

Synonym: HNE_1139

Alternate gene names: 114799782

Gene position: 1151110-1150739 (Counterclockwise)

Preceding gene: 114799994

Following gene: 114797248

Centisome position: 31.07

GC content: 64.78

Gene sequence:

>372_bases
GTGATGAAACGCGCTACTGCCACTGCCCTCGCCCTCACCGCCTTCGCGCTTCCGGCTTTTGCGGACGCGGGCGGCATCGA
CTCGACCGTCTTCCTGGCGGCCATCTTCGCGCTGGCCTGCTTTGTCGGCTACTACGTCGTCTGGTCGGTCACCCCCGCGC
TGCACACGCCGCTGATGGCTGTGACCAACGCGATTTCCTCCGTGATCGTCGTCGGCGCGCTCGTTGCCGCCGCCGCCCAT
GGCCTTTCTTCTGAAGGCTGGATTGCCAAGATCCTCGGCGCCATCGCCGTGGCCCTTGCCAGCGTCAACATCTTCGGCGG
CTTCCTCGTCACCCAGCGCATGCTGGCCATGTATAAGAAGAAGGGGCAGTAG

Upstream 100 bases:

>100_bases
TCACCGCCGAAAACGGCGCGATCAATCTCGATACCGAGGATGAAGTCGTCGTTGCCATGCTGCTCACGCGCAATGGCGCA
ACCGTTAGTGAAAGGCTGAA

Downstream 100 bases:

>100_bases
TCTTGGAACAGTTCAACTCGACCTGGGCGCCCCTGCTCTATCTCGTCTCGGGCATCCTCTTCATCCTGGCCCTGCGCGGC
CTTTCCAGCCCGGCCACCAG

Product: NAD(P) transhydrogenase subunit alpha part 2

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Proton-translocating transhydrogenase component 2; Pyridine nucleotide transhydrogenase subunit alpha 2; dII [H]

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MMKRATATALALTAFALPAFADAGGIDSTVFLAAIFALACFVGYYVVWSVTPALHTPLMAVTNAISSVIVVGALVAAAAH
GLSSEGWIAKILGAIAVALASVNIFGGFLVTQRMLAMYKKKGQ

Sequences:

>Translated_123_residues
MMKRATATALALTAFALPAFADAGGIDSTVFLAAIFALACFVGYYVVWSVTPALHTPLMAVTNAISSVIVVGALVAAAAH
GLSSEGWIAKILGAIAVALASVNIFGGFLVTQRMLAMYKKKGQ
>Mature_123_residues
MMKRATATALALTAFALPAFADAGGIDSTVFLAAIFALACFVGYYVVWSVTPALHTPLMAVTNAISSVIVVGALVAAAAH
GLSSEGWIAKILGAIAVALASVNIFGGFLVTQRMLAMYKKKGQ

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=85, Percent_Identity=55.2941176470588, Blast_Score=89, Evalue=6e-19,
Organism=Homo sapiens, GI122939153, Length=85, Percent_Identity=55.2941176470588, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1787887, Length=87, Percent_Identity=62.0689655172414, Blast_Score=107, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17550456, Length=90, Percent_Identity=52.2222222222222, Blast_Score=88, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 12605; Mature: 12605

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKRATATALALTAFALPAFADAGGIDSTVFLAAIFALACFVGYYVVWSVTPALHTPLMA
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
VTNAISSVIVVGALVAAAAHGLSSEGWIAKILGAIAVALASVNIFGGFLVTQRMLAMYKK
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGQ
CCC
>Mature Secondary Structure
MMKRATATALALTAFALPAFADAGGIDSTVFLAAIFALACFVGYYVVWSVTPALHTPLMA
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
VTNAISSVIVVGALVAAAAHGLSSEGWIAKILGAIAVALASVNIFGGFLVTQRMLAMYKK
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]