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The map label for this gene is trpD

Identifier: 114797113

GI number: 114797113

Start: 1832016

End: 1833041

Strand: Reverse

Name: trpD

Synonym: HNE_1788

Alternate gene names: 114797113

Gene position: 1833041-1832016 (Counterclockwise)

Preceding gene: 114798771

Following gene: 114800153

Centisome position: 49.47

GC content: 60.72

Gene sequence:

>1026_bases
GTGAGCGAGAGCGCGCTTAACACCGCCATTCAGGCTATCGCGCGCGGTCTGCCTCTGGAAGAATCCGTGCTTGAAGGCGC
GTTTGACACGCTCCTTTCCGGGGAGGCTGCTCCAGAGGAAGTCGGCGCATTTCTGGCGGGGCTGACCGTTCGGGGCGAAA
CGGCCAATGAGCTGATCGCCGGCGCGCGTATAATGCGCCGTCACGGGCGCAGCGTATCTGTCGAGGGACCACTGCTCGAC
ACATGCGGGACGGGTGGGTTGCCGTGGAAATCCCTCAACACGTCCACTGCCAGTGCCATCGTCATTGCTGCCGCCGGTGG
GAGGGTGGCCAAACATGGCAATCGCTCCGTGCCGCCCAAGACGGGGTCCGCCGATGTGCTGGAAGCCCTGGGCCTGCAAC
TGGAGCTGAGTGACACCGCATTCAAATCCTGCCTGGAGATTGCGGGCGTGGGCTTTCTGTTTGCTCGCAGTTATCATTCA
GCAATGCGCCATGTAGCCCCCATCCGCCATAAGCTGGGTATTCGGACGATTTTCAATCTACTCGGCCCTCTTTCCAATCC
AGCAGGGGCGGAATACTCCGTTCTCGGCGTATATGACAAACAGTGGGTCACACCCATGGCTGAGGCGTTGAAAGCTCTTG
GCACCCGCTGCGCATGGGTGGTTCATGGGCTGGCCGGCATCGACGAAATATCTATCTCTGGTCCTACTGACGTTTGCGAA
GTTACGCCCGCCTCCATTCGCCATTTTCAAATCACACCTTCAGATGCCGGCCTGCCGAGCCATCCTCTGTCGACGCTTGA
AGGCGGCGCCCCGGAAGAAAACACGGCCGCCATCCGAGATCTGCTTGATGGCCGCGAGGGCCCATTCCGAGACATCGTGC
TGATCAATGCGGCAGCGGGCCTGCATGTGAGCGGCATGGTTGCTGATTTGCCAGCGGGCGTGCAGCGCGCAGCGCAAGCG
ATTGACAGCGGAGCGGCAAGAGAAACCCTCAACACGCTGGTACGCACATCTCGGGAGAGCGATTGA

Upstream 100 bases:

>100_bases
ACAAAACCCGTCCTGTCTATGGGGTTCAGTTTCATCCCGAGAGTATCCTGACCGAGCATGGCCATGCGCTGCTGAAGAAC
TTTCTGAAAAAGGTGAAACC

Downstream 100 bases:

>100_bases
GCATGAAAACCGCGCTGGACCGGATCATTGACTACAAGCGTGATGAAGTCCGCGCGCTGAAGAAGGATCGCTCCCTTGGC
GAACTGGAAAATGCGGCGGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSESALNTAIQAIARGLPLEESVLEGAFDTLLSGEAAPEEVGAFLAGLTVRGETANELIAGARIMRRHGRSVSVEGPLLD
TCGTGGLPWKSLNTSTASAIVIAAAGGRVAKHGNRSVPPKTGSADVLEALGLQLELSDTAFKSCLEIAGVGFLFARSYHS
AMRHVAPIRHKLGIRTIFNLLGPLSNPAGAEYSVLGVYDKQWVTPMAEALKALGTRCAWVVHGLAGIDEISISGPTDVCE
VTPASIRHFQITPSDAGLPSHPLSTLEGGAPEENTAAIRDLLDGREGPFRDIVLINAAAGLHVSGMVADLPAGVQRAAQA
IDSGAARETLNTLVRTSRESD

Sequences:

>Translated_341_residues
MSESALNTAIQAIARGLPLEESVLEGAFDTLLSGEAAPEEVGAFLAGLTVRGETANELIAGARIMRRHGRSVSVEGPLLD
TCGTGGLPWKSLNTSTASAIVIAAAGGRVAKHGNRSVPPKTGSADVLEALGLQLELSDTAFKSCLEIAGVGFLFARSYHS
AMRHVAPIRHKLGIRTIFNLLGPLSNPAGAEYSVLGVYDKQWVTPMAEALKALGTRCAWVVHGLAGIDEISISGPTDVCE
VTPASIRHFQITPSDAGLPSHPLSTLEGGAPEENTAAIRDLLDGREGPFRDIVLINAAAGLHVSGMVADLPAGVQRAAQA
IDSGAARETLNTLVRTSRESD
>Mature_340_residues
SESALNTAIQAIARGLPLEESVLEGAFDTLLSGEAAPEEVGAFLAGLTVRGETANELIAGARIMRRHGRSVSVEGPLLDT
CGTGGLPWKSLNTSTASAIVIAAAGGRVAKHGNRSVPPKTGSADVLEALGLQLELSDTAFKSCLEIAGVGFLFARSYHSA
MRHVAPIRHKLGIRTIFNLLGPLSNPAGAEYSVLGVYDKQWVTPMAEALKALGTRCAWVVHGLAGIDEISISGPTDVCEV
TPASIRHFQITPSDAGLPSHPLSTLEGGAPEENTAAIRDLLDGREGPFRDIVLINAAAGLHVSGMVADLPAGVQRAAQAI
DSGAARETLNTLVRTSRESD

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=331, Percent_Identity=36.8580060422961, Blast_Score=190, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6320561, Length=326, Percent_Identity=30.9815950920245, Blast_Score=125, Evalue=7e-30,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_HYPNA (Q0C1A1)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_760492.1
- ProteinModelPortal:   Q0C1A1
- SMR:   Q0C1A1
- STRING:   Q0C1A1
- GeneID:   4287141
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_1788
- NMPDR:   fig|228405.5.peg.1721
- TIGR:   HNE_1788
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- PhylomeDB:   Q0C1A1
- ProtClustDB:   CLSK2531597
- BioCyc:   HNEP81032:HNE_1788-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35448; Mature: 35316

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESALNTAIQAIARGLPLEESVLEGAFDTLLSGEAAPEEVGAFLAGLTVRGETANELIA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCEECCCCHHHHHH
GARIMRRHGRSVSVEGPLLDTCGTGGLPWKSLNTSTASAIVIAAAGGRVAKHGNRSVPPK
HHHHHHHCCCEEEECCCCHHCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHCCCCCCCCC
TGSADVLEALGLQLELSDTAFKSCLEIAGVGFLFARSYHSAMRHVAPIRHKLGIRTIFNL
CCCHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGPLSNPAGAEYSVLGVYDKQWVTPMAEALKALGTRCAWVVHGLAGIDEISISGPTDVCE
HCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHH
VTPASIRHFQITPSDAGLPSHPLSTLEGGAPEENTAAIRDLLDGREGPFRDIVLINAAAG
CCCCCCEEEEECCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCC
LHVSGMVADLPAGVQRAAQAIDSGAARETLNTLVRTSRESD
CCCCCHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SESALNTAIQAIARGLPLEESVLEGAFDTLLSGEAAPEEVGAFLAGLTVRGETANELIA
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCEECCCCHHHHHH
GARIMRRHGRSVSVEGPLLDTCGTGGLPWKSLNTSTASAIVIAAAGGRVAKHGNRSVPPK
HHHHHHHCCCEEEECCCCHHCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHCCCCCCCCC
TGSADVLEALGLQLELSDTAFKSCLEIAGVGFLFARSYHSAMRHVAPIRHKLGIRTIFNL
CCCHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGPLSNPAGAEYSVLGVYDKQWVTPMAEALKALGTRCAWVVHGLAGIDEISISGPTDVCE
HCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHH
VTPASIRHFQITPSDAGLPSHPLSTLEGGAPEENTAAIRDLLDGREGPFRDIVLINAAAG
CCCCCCEEEEECCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCC
LHVSGMVADLPAGVQRAAQAIDSGAARETLNTLVRTSRESD
CCCCCHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA