Click here to switch to the map view.

The map label for this gene is trpG [H]

Identifier: 114798771

GI number: 114798771

Start: 1833038

End: 1833610

Strand: Reverse

Name: trpG [H]

Synonym: HNE_1789

Alternate gene names: 114798771

Gene position: 1833610-1833038 (Counterclockwise)

Preceding gene: 114799062

Following gene: 114797113

Centisome position: 49.49

GC content: 55.5

Gene sequence:

>573_bases
ATGATCCTCGTTATCGACAATTATGACAGCTTCACCTGGAACCTCGTCCATTATCTGGAAGAACTCGGCGCCAAAACACA
CGTTGTCCGCAATGATCAGCTCACTGTAGATGAAGCCCTTGCGCTCAAGCCGGATGCGTTGCTCCTTTCGCCCGGCCCCT
GCACACCAAATGAGGCCGGCATCTGCCTGGACCTTCTGAAGGCGGCTCCAGACGATCTTCCGGTACTTGGCGTCTGCCTC
GGTCATCAGGCAATCGGACAGGCGTTCGGCGGTGCGGTCATCCATGCCCGCGAGATCCGCCATGGGAAGATTTCCGAGAT
TGAAACCAATCAGTCTGGTCTCTTTGAAGGCCTTCCCGAGCGCTACCAGGTTGTGCGTTACCACTCCCTGGCTATCCGCA
CTGACGATCTACCGGATTGCCTGCTGGCAGACGCCCATACCGATGACGGAGAGATTATGGCGGTTCATCACAAAACCCGT
CCTGTCTATGGGGTTCAGTTTCATCCCGAGAGTATCCTGACCGAGCATGGCCATGCGCTGCTGAAGAACTTTCTGAAAAA
GGTGAAACCGTGA

Upstream 100 bases:

>100_bases
TGCTCGATTCCAATGCTCAGTATGAATATGATGAAACGGTTCACAAATCCGGCGCCCTGAAGCGTGCTGCCGAATTGGCC
GCAGCTTATGAGCACGACCA

Downstream 100 bases:

>100_bases
GCGAGAGCGCGCTTAACACCGCCATTCAGGCTATCGCGCGCGGTCTGCCTCTGGAAGAATCCGTGCTTGAAGGCGCGTTT
GACACGCTCCTTTCCGGGGA

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MILVIDNYDSFTWNLVHYLEELGAKTHVVRNDQLTVDEALALKPDALLLSPGPCTPNEAGICLDLLKAAPDDLPVLGVCL
GHQAIGQAFGGAVIHAREIRHGKISEIETNQSGLFEGLPERYQVVRYHSLAIRTDDLPDCLLADAHTDDGEIMAVHHKTR
PVYGVQFHPESILTEHGHALLKNFLKKVKP

Sequences:

>Translated_190_residues
MILVIDNYDSFTWNLVHYLEELGAKTHVVRNDQLTVDEALALKPDALLLSPGPCTPNEAGICLDLLKAAPDDLPVLGVCL
GHQAIGQAFGGAVIHAREIRHGKISEIETNQSGLFEGLPERYQVVRYHSLAIRTDDLPDCLLADAHTDDGEIMAVHHKTR
PVYGVQFHPESILTEHGHALLKNFLKKVKP
>Mature_190_residues
MILVIDNYDSFTWNLVHYLEELGAKTHVVRNDQLTVDEALALKPDALLLSPGPCTPNEAGICLDLLKAAPDDLPVLGVCL
GHQAIGQAFGGAVIHAREIRHGKISEIETNQSGLFEGLPERYQVVRYHSLAIRTDDLPDCLLADAHTDDGEIMAVHHKTR
PVYGVQFHPESILTEHGHALLKNFLKKVKP

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI4504035, Length=114, Percent_Identity=37.719298245614, Blast_Score=71, Evalue=6e-13,
Organism=Escherichia coli, GI1789760, Length=187, Percent_Identity=55.0802139037433, Blast_Score=214, Evalue=4e-57,
Organism=Escherichia coli, GI1787517, Length=196, Percent_Identity=43.3673469387755, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786215, Length=182, Percent_Identity=25.2747252747253, Blast_Score=61, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=185, Percent_Identity=50.2702702702703, Blast_Score=190, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6324361, Length=210, Percent_Identity=35.7142857142857, Blast_Score=108, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 20949; Mature: 20949

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00442 GATASE_TYPE_I ; PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVIDNYDSFTWNLVHYLEELGAKTHVVRNDQLTVDEALALKPDALLLSPGPCTPNEAG
CEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHEECCCEEEECCCCCCCCCCH
ICLDLLKAAPDDLPVLGVCLGHQAIGQAFGGAVIHAREIRHGKISEIETNQSGLFEGLPE
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEECCCCHHHHCCHH
RYQVVRYHSLAIRTDDLPDCLLADAHTDDGEIMAVHHKTRPVYGVQFHPESILTEHGHAL
HHHHHHHHEEEEECCCCCCCEEECCCCCCCCEEEEEECCCCEEEEEECCHHHHHHCCHHH
LKNFLKKVKP
HHHHHHHCCC
>Mature Secondary Structure
MILVIDNYDSFTWNLVHYLEELGAKTHVVRNDQLTVDEALALKPDALLLSPGPCTPNEAG
CEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHEECCCEEEECCCCCCCCCCH
ICLDLLKAAPDDLPVLGVCLGHQAIGQAFGGAVIHAREIRHGKISEIETNQSGLFEGLPE
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEECCCCHHHHCCHH
RYQVVRYHSLAIRTDDLPDCLLADAHTDDGEIMAVHHKTRPVYGVQFHPESILTEHGHAL
HHHHHHHHEEEEECCCCCCCEEECCCCCCCCEEEEEECCCCEEEEEECCHHHHHHCCHHH
LKNFLKKVKP
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2105306; 10984043 [H]