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The map label for this gene is ybhO [H]

Identifier: 114332257

GI number: 114332257

Start: 2422708

End: 2423865

Strand: Reverse

Name: ybhO [H]

Synonym: Neut_2297

Alternate gene names: 114332257

Gene position: 2423865-2422708 (Counterclockwise)

Preceding gene: 114332258

Following gene: 114332256

Centisome position: 91.09

GC content: 48.36

Gene sequence:

>1158_bases
ATGAGTTTGCCTGATTTTGTCGAAGGAAACTGTATAACACTACTGCATTCCGGCACGGAATATTTCCCGGTGCTGGAATC
GGCCATTGATTCGACCAGGCAGGAAATTTATCTCGAAACTTATATTTTTCAGTACGATACAACCGGTATCCGAATTGCTG
AAGCGCTTAAACGGGCAGCACAACGCGGGGTAGCTGTCCATCTGTTGATTGATGGATTTGGCTCGCTCAGCCTGCCCGGG
AAAGTAATTCGGGAGATGCTTGCAGCAGGTGTGCGAGTACTGATATATCGGCCGGAGTTTTTTTCATTCCGGCTCAAACG
CTCCCGCTTGCGTCGTATGCATCGCAAACTGGCGGTTATGGATGCCAGTTTGGCATTTGTGGGAGGAATTAATATTGTCG
ATGATTGCTACGAATCTGATGCGTTATTTCCACGATTCGATTATGCTGTTCAAATTATCGGTCCGCTACTGGAAAAAATT
CATGCTACAGCAAGGCATCTGTGGATGTTGGTTGCATGGGTTTATTTCAAAAAGCGCTGGACAAATTATTTGTCTGTTGT
CAGCAATAATCTGCCGGCAGGCCATCAGCGTGCATCGTTGGTTATCCGGGATAATCTGCGTAACCGGCGTAGTATTGAGC
ATTGCTATCTCAGGGCAATAGCGGTTGCTCGCAAGGAAATCATTATTGCCAATGCCTATTTTCTTCCCGGGAAGAATTTT
CGGCAGGCTCTGATCAAGGCCGCGCAGCGTGGTGTCTCGGTTATCCTTCTGCTACAGGGGAAATCGGAATATCGCTTGCA
ATATTACGCCATGCATGCCCTGTATGGCCACCTGCTGGATGCCGGTATCCGTATCTACGAGTACCGGCAAGGGTATCTGC
ATGCCAAAGTGGCAGTTATTGACGGCTCCTGGTCTACTGTTGGTTCTTCCAATATTGATCCGTTCAGTTTATTGCTGGCA
CGTGAGGCCAATGTCATTATCTTAGATCGGATATTTGCAGCGGGATTACGGGGCAGTCTGCAACGGACATTGGAAGTCTC
TTGTCCGGTGTTACAGCATTCCTGGAGAGGCCGGTCACGAATTAAACGTTCGCTGAACTGGATATGCTATTACTTCATCC
GGATGGCGTGGGGATTACTGGGATACCGTCGGGACTAA

Upstream 100 bases:

>100_bases
ATATCCGTGGTTTTCAGGTAAAAAATGCCCGGATTTTTCATAATCGCCCCTGGTCCAGAATTTCAGACCATGCTGCGTTG
TCGGCCCAGATTATGCGTAA

Downstream 100 bases:

>100_bases
GATCCCTTGGCCGCTTTAATACGATCTTGTCGCATACTCGGATACGGAATAACCAATGCCCGATTGCCATTTTCTTTTGT
GGGCCAGTGTTTCATCAAAG

Product: phospholipase D/transphosphatidylase

Products: NA

Alternate protein names: CL synthase [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MSLPDFVEGNCITLLHSGTEYFPVLESAIDSTRQEIYLETYIFQYDTTGIRIAEALKRAAQRGVAVHLLIDGFGSLSLPG
KVIREMLAAGVRVLIYRPEFFSFRLKRSRLRRMHRKLAVMDASLAFVGGINIVDDCYESDALFPRFDYAVQIIGPLLEKI
HATARHLWMLVAWVYFKKRWTNYLSVVSNNLPAGHQRASLVIRDNLRNRRSIEHCYLRAIAVARKEIIIANAYFLPGKNF
RQALIKAAQRGVSVILLLQGKSEYRLQYYAMHALYGHLLDAGIRIYEYRQGYLHAKVAVIDGSWSTVGSSNIDPFSLLLA
REANVIILDRIFAAGLRGSLQRTLEVSCPVLQHSWRGRSRIKRSLNWICYYFIRMAWGLLGYRRD

Sequences:

>Translated_385_residues
MSLPDFVEGNCITLLHSGTEYFPVLESAIDSTRQEIYLETYIFQYDTTGIRIAEALKRAAQRGVAVHLLIDGFGSLSLPG
KVIREMLAAGVRVLIYRPEFFSFRLKRSRLRRMHRKLAVMDASLAFVGGINIVDDCYESDALFPRFDYAVQIIGPLLEKI
HATARHLWMLVAWVYFKKRWTNYLSVVSNNLPAGHQRASLVIRDNLRNRRSIEHCYLRAIAVARKEIIIANAYFLPGKNF
RQALIKAAQRGVSVILLLQGKSEYRLQYYAMHALYGHLLDAGIRIYEYRQGYLHAKVAVIDGSWSTVGSSNIDPFSLLLA
REANVIILDRIFAAGLRGSLQRTLEVSCPVLQHSWRGRSRIKRSLNWICYYFIRMAWGLLGYRRD
>Mature_384_residues
SLPDFVEGNCITLLHSGTEYFPVLESAIDSTRQEIYLETYIFQYDTTGIRIAEALKRAAQRGVAVHLLIDGFGSLSLPGK
VIREMLAAGVRVLIYRPEFFSFRLKRSRLRRMHRKLAVMDASLAFVGGINIVDDCYESDALFPRFDYAVQIIGPLLEKIH
ATARHLWMLVAWVYFKKRWTNYLSVVSNNLPAGHQRASLVIRDNLRNRRSIEHCYLRAIAVARKEIIIANAYFLPGKNFR
QALIKAAQRGVSVILLLQGKSEYRLQYYAMHALYGHLLDAGIRIYEYRQGYLHAKVAVIDGSWSTVGSSNIDPFSLLLAR
EANVIILDRIFAAGLRGSLQRTLEVSCPVLQHSWRGRSRIKRSLNWICYYFIRMAWGLLGYRRD

Specific function: Catalyzes, in vitro, the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol [H]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI1787007, Length=376, Percent_Identity=38.8297872340425, Blast_Score=244, Evalue=6e-66,
Organism=Escherichia coli, GI1787502, Length=377, Percent_Identity=29.1777188328912, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: 2.7.8.-

Molecular weight: Translated: 44152; Mature: 44021

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPDFVEGNCITLLHSGTEYFPVLESAIDSTRQEIYLETYIFQYDTTGIRIAEALKRAA
CCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHEEEEEEEEEECCCCHHHHHHHHHHH
QRGVAVHLLIDGFGSLSLPGKVIREMLAAGVRVLIYRPEFFSFRLKRSRLRRMHRKLAVM
HCCCEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
DASLAFVGGINIVDDCYESDALFPRFDYAVQIIGPLLEKIHATARHLWMLVAWVYFKKRW
HHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNYLSVVSNNLPAGHQRASLVIRDNLRNRRSIEHCYLRAIAVARKEIIIANAYFLPGKNF
HHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHEEEEEEEECCCCHH
RQALIKAAQRGVSVILLLQGKSEYRLQYYAMHALYGHLLDAGIRIYEYRQGYLHAKVAVI
HHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEEEE
DGSWSTVGSSNIDPFSLLLAREANVIILDRIFAAGLRGSLQRTLEVSCPVLQHSWRGRSR
ECCCCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHH
IKRSLNWICYYFIRMAWGLLGYRRD
HHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLPDFVEGNCITLLHSGTEYFPVLESAIDSTRQEIYLETYIFQYDTTGIRIAEALKRAA
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHEEEEEEEEEECCCCHHHHHHHHHHH
QRGVAVHLLIDGFGSLSLPGKVIREMLAAGVRVLIYRPEFFSFRLKRSRLRRMHRKLAVM
HCCCEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
DASLAFVGGINIVDDCYESDALFPRFDYAVQIIGPLLEKIHATARHLWMLVAWVYFKKRW
HHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNYLSVVSNNLPAGHQRASLVIRDNLRNRRSIEHCYLRAIAVARKEIIIANAYFLPGKNF
HHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHEEEEEEEECCCCHH
RQALIKAAQRGVSVILLLQGKSEYRLQYYAMHALYGHLLDAGIRIYEYRQGYLHAKVAVI
HHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEEEE
DGSWSTVGSSNIDPFSLLLAREANVIILDRIFAAGLRGSLQRTLEVSCPVLQHSWRGRSR
ECCCCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHH
IKRSLNWICYYFIRMAWGLLGYRRD
HHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]