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The map label for this gene is apaH [H]

Identifier: 114331922

GI number: 114331922

Start: 2062874

End: 2063674

Strand: Direct

Name: apaH [H]

Synonym: Neut_1949

Alternate gene names: 114331922

Gene position: 2062874-2063674 (Clockwise)

Preceding gene: 114331921

Following gene: 114331930

Centisome position: 77.52

GC content: 50.81

Gene sequence:

>801_bases
ATGGCAACTTATGCAATTGGTGACCTACAAGGCTGTCACCGACATTTTCTTGACCTGCTTGACCTGACTGGCTTCAATTC
CACGCGGGATAGGTTGTGGCTGGTGGGCGATATCGTTAACCGCGGCCCTGACTCCCTCTCATTATTGCGTACTTTGATGG
CACTGGGAGATACCGTCACAATGGTACTCGGCAACCATGATCTTCATCTTTTGGCAGTCGCTGCCGGTTCTGCCCAACTG
AAACACGGGGACACCTTGCAACCACTTCTGGATGCTCAGGATAGCAAAGTTCTGCTTGACTGGCTGAAGTGCCAGCGATT
GTTCTATCACGAAGATGAATACGCCCTAGTCCATGCCGGGCTATTACCCGCCTGGCACACTGAACAAGCGGCGATGCTGG
CACAAGAGGTTGAAGCAATCATCCACAGTGATCAATTTCAAATGTTTTCTCAATCAATGTATGGCAATGCACCTGATTGC
TGGCAGGATACATTACGGGGAGAAAGCCGCTGGCGAGTCATCATTAACGCTATGACACGCATGCGCGTCTGTTCACCCAA
AGGCAGAATGAATTTTTCCTACAAGGAAGGATTGTCCGCTATTCCCCAGGGATTGCTGCCCTGGTTTGAGATTCCCTGGC
GTGCCAGCAAAGATGCAACGATTGTATTTGGGCATTGGTCTGCGCTGGGATTACATCTGACGCCCAATCTGATTGCTCTG
GATACGGGATGCGTCTGGCAAGGCTGCCTGACAGCTATTCGACTGGAAGACAGGAAGGTATTTCAGGTACCGTGTGCATA
A

Upstream 100 bases:

>100_bases
CGTTTGTAGAGAAGTTTAAAGGCGCAGGTGGAAAAATTTAGCTTAATTTTAATCAAGTACAATACAGCACTGCTAATTAA
TCTATATTTTCCTGATCTTA

Downstream 100 bases:

>100_bases
TCTTCAGTGATAACGCTTGAGCAATGGCCTTTTCCGCCAGACGTGCAAGTTCGCGGCGGTTTTTATCATCTCCGGGAATG
GGGCTCATGAAATTTAATTC

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MATYAIGDLQGCHRHFLDLLDLTGFNSTRDRLWLVGDIVNRGPDSLSLLRTLMALGDTVTMVLGNHDLHLLAVAAGSAQL
KHGDTLQPLLDAQDSKVLLDWLKCQRLFYHEDEYALVHAGLLPAWHTEQAAMLAQEVEAIIHSDQFQMFSQSMYGNAPDC
WQDTLRGESRWRVIINAMTRMRVCSPKGRMNFSYKEGLSAIPQGLLPWFEIPWRASKDATIVFGHWSALGLHLTPNLIAL
DTGCVWQGCLTAIRLEDRKVFQVPCA

Sequences:

>Translated_266_residues
MATYAIGDLQGCHRHFLDLLDLTGFNSTRDRLWLVGDIVNRGPDSLSLLRTLMALGDTVTMVLGNHDLHLLAVAAGSAQL
KHGDTLQPLLDAQDSKVLLDWLKCQRLFYHEDEYALVHAGLLPAWHTEQAAMLAQEVEAIIHSDQFQMFSQSMYGNAPDC
WQDTLRGESRWRVIINAMTRMRVCSPKGRMNFSYKEGLSAIPQGLLPWFEIPWRASKDATIVFGHWSALGLHLTPNLIAL
DTGCVWQGCLTAIRLEDRKVFQVPCA
>Mature_265_residues
ATYAIGDLQGCHRHFLDLLDLTGFNSTRDRLWLVGDIVNRGPDSLSLLRTLMALGDTVTMVLGNHDLHLLAVAAGSAQLK
HGDTLQPLLDAQDSKVLLDWLKCQRLFYHEDEYALVHAGLLPAWHTEQAAMLAQEVEAIIHSDQFQMFSQSMYGNAPDCW
QDTLRGESRWRVIINAMTRMRVCSPKGRMNFSYKEGLSAIPQGLLPWFEIPWRASKDATIVFGHWSALGLHLTPNLIALD
TGCVWQGCLTAIRLEDRKVFQVPCA

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=267, Percent_Identity=47.565543071161, Blast_Score=246, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 29869; Mature: 29738

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATYAIGDLQGCHRHFLDLLDLTGFNSTRDRLWLVGDIVNRGPDSLSLLRTLMALGDTVT
CCCEECCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHCCCCHHHHHHHHHHCCCEEE
MVLGNHDLHLLAVAAGSAQLKHGDTLQPLLDAQDSKVLLDWLKCQRLFYHEDEYALVHAG
EEECCCCEEEEEEECCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEEC
LLPAWHTEQAAMLAQEVEAIIHSDQFQMFSQSMYGNAPDCWQDTLRGESRWRVIINAMTR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHH
MRVCSPKGRMNFSYKEGLSAIPQGLLPWFEIPWRASKDATIVFGHWSALGLHLTPNLIAL
HHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCEEEEEEECCCEEEE
DTGCVWQGCLTAIRLEDRKVFQVPCA
ECCHHHHHHHHHHEECCCEEEECCCC
>Mature Secondary Structure 
ATYAIGDLQGCHRHFLDLLDLTGFNSTRDRLWLVGDIVNRGPDSLSLLRTLMALGDTVT
CCEECCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHCCCCHHHHHHHHHHCCCEEE
MVLGNHDLHLLAVAAGSAQLKHGDTLQPLLDAQDSKVLLDWLKCQRLFYHEDEYALVHAG
EEECCCCEEEEEEECCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEEC
LLPAWHTEQAAMLAQEVEAIIHSDQFQMFSQSMYGNAPDCWQDTLRGESRWRVIINAMTR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHH
MRVCSPKGRMNFSYKEGLSAIPQGLLPWFEIPWRASKDATIVFGHWSALGLHLTPNLIAL
HHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCEEEEEEECCCEEEE
DTGCVWQGCLTAIRLEDRKVFQVPCA
ECCHHHHHHHHHHEECCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]