Click here to switch to the map view.

The map label for this gene is bepG [H]

Identifier: 114331921

GI number: 114331921

Start: 2062418

End: 2062678

Strand: Direct

Name: bepG [H]

Synonym: Neut_1948

Alternate gene names: 114331921

Gene position: 2062418-2062678 (Clockwise)

Preceding gene: 114331920

Following gene: 114331922

Centisome position: 77.5

GC content: 45.59

Gene sequence:

>261_bases
TTGTCGATAGTTGAAGCAGCCATCAAATCCGCCCAACTCCGTTTTAGAGCAGTCATGATGACTGCGATTTCCTTCATTCT
CGGTGTGCTCCCATTAGTCGTCGCATCAGGCGCAGGCGCAGCAAGTCGTCAATCACTTGGAACCGTTGTTTTTGGAGGAA
TGCTGGTTTCAGCAATCATTGGAACAATTTTAATTCCGGCTTTTTACGTGATCATTCAATCTATGACGGAAAACATGCGG
CAACCAAAAACTCGCCTTTAA

Upstream 100 bases:

>100_bases
ATATTTACGCCCAGATTGGTCTCGTCATGTTGGTCGGTATGGCTTCAAAAAACGCAATCCTTATCGTCGAATTTGCTAAA
GTGCAAAGAGAGAGAGTGGG

Downstream 100 bases:

>100_bases
GCATATTAATTTGCAAAATGGCAACTGGCAATTGTCTTCTTAAAATAGGACTGAATACCCGAGTAAAAAGCAAAGCGTGT
TTCAGAAAATTGCGGCGTTT

Product: putative multidrug efflux membrane fusion protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 86; Mature: 85

Protein sequence:

>86_residues
MSIVEAAIKSAQLRFRAVMMTAISFILGVLPLVVASGAGAASRQSLGTVVFGGMLVSAIIGTILIPAFYVIIQSMTENMR
QPKTRL

Sequences:

>Translated_86_residues
MSIVEAAIKSAQLRFRAVMMTAISFILGVLPLVVASGAGAASRQSLGTVVFGGMLVSAIIGTILIPAFYVIIQSMTENMR
QPKTRL
>Mature_85_residues
SIVEAAIKSAQLRFRAVMMTAISFILGVLPLVVASGAGAASRQSLGTVVFGGMLVSAIIGTILIPAFYVIIQSMTENMRQ
PKTRL

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: COG0841

COG function: function code V; Cation/multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AcrB/AcrD/AcrF (TC 2.A.6) family [H]

Homologues:

Organism=Escherichia coli, GI1788814, Length=72, Percent_Identity=34.7222222222222, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI1789930, Length=57, Percent_Identity=45.6140350877193, Blast_Score=62, Evalue=5e-12,
Organism=Escherichia coli, GI1786667, Length=58, Percent_Identity=39.6551724137931, Blast_Score=60, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036
- InterPro:   IPR004764 [H]

Pfam domain/function: PF00873 ACR_tran [H]

EC number: NA

Molecular weight: Translated: 9083; Mature: 8952

Theoretical pI: Translated: 11.97; Mature: 11.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVEAAIKSAQLRFRAVMMTAISFILGVLPLVVASGAGAASRQSLGTVVFGGMLVSAII
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
GTILIPAFYVIIQSMTENMRQPKTRL
HHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SIVEAAIKSAQLRFRAVMMTAISFILGVLPLVVASGAGAASRQSLGTVVFGGMLVSAII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
GTILIPAFYVIIQSMTENMRQPKTRL
HHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]