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The map label for this gene is aroC

Identifier: 114331930

GI number: 114331930

Start: 2071924

End: 2073096

Strand: Direct

Name: aroC

Synonym: Neut_1957

Alternate gene names: 114331930

Gene position: 2071924-2073096 (Clockwise)

Preceding gene: 114331922

Following gene: 114331931

Centisome position: 77.86

GC content: 52.86

Gene sequence:

>1173_bases
ATGTCTGGCAATACCATCGGAAAGCTGTTTTGCGTCACTTCATTTGGTGAATCCCACGGCCCGGCGATCGGCTGTATCGT
GGACGGATGCCCCCCCGGGCTAGTGTTATCTGCCATGGATATTCAGCTGGAGCTCGATCGACGCAAACCTGGCACTTCCC
GACATGTCACCCAACGGCATGAGGGAGATCGGGTGGAAATACTCTCGGGCGTATTTGACAACATCACAACGGGGACACCA
ATTGCTCTGCTGATTCGTAATGAAGATCAGCGCAGCAAGGATTACAGTAAGATCATGGATGTGTTCCGTCCTGGCCATGC
AGATTACACCTACTGGCAAAAATACGGCATTCGCGATTATCGTGGTGGCGGTCGTTCATCCGCACGGGAAACGGCTGTGC
GGGTAGCAGCTGGCGCTATTGCCAAAAAATGGCTGCATGAACGCTATGGCATTGTCATTCGGGGCTATATGGCGCAGCTT
GGCCCAATCGCCATTCCCTTTAAAAACTGGGAAGTCATCAACCAGAATCCTTTTTTTGTCGCGGATGATGACTACGTTCC
CAAACTGGAAGCATTTATGGATGCCTTGCGCAAATCAGGCGATTCAGCGGGTGCCCGGATCAATGTAATAGCGGAAGGTG
TGCCTGTTGGCTGGGGTGAACCGGTTTACGACCGGCTGGATGCTGATATTGCTTACGCCATGATGAGTATCAACGCAGCC
AAGGGGGTAGAAATCGGTGCAGGATTCAATAGTGTGACGCAAAAAGGAACAGAACACTCGGATGAAATCACACCCGAAGG
ATTTCTGAGCAACAATGCCGGTGGAATTCTGGGAGGTATTTCCAGCAGCCAGCCGATTACCGTCAGCGTAGCGATCAAGC
CCACCTCGAGCATCCGGCTCGGGCGACGTTCTATCGACAAGGCCGGCAATCCCGTGATTGTTGAAACCCACGGCAGACAC
GACCCCTGCGTCGGCATCCGGGCAACACCTATCGTGGAAGCGATGCTGGCTATCGTCTTGATGGATCATGCCCTGCGTCA
TCGAGGACAGAATGAAGATGTGGTTTGTACCACTCCCAAAGTTCCCGGAAATATCATCAACCCGACAAATCCGGTAACAA
CACAACCCGACGTACGCCGGGCTGAAGATCCGGAACCGGATGAAAATTCGTAA

Upstream 100 bases:

>100_bases
TTAGCACGCTGATACCACGCCACCACTCAATTGTCATCCCATCTCTCCGTTTTGGCTTATGTTAGACTCCATGATTTCCT
CGTTTAACCAAGGATCTGTA

Downstream 100 bases:

>100_bases
ACAGATTATTTACCCCAGAAAAACAGGTAATTCTCAACTCTGCCTCTCTCACATCAACTCGTCGCTGAGAACTAAAAAAA
TCACTGATCAAGCAACAACA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MSGNTIGKLFCVTSFGESHGPAIGCIVDGCPPGLVLSAMDIQLELDRRKPGTSRHVTQRHEGDRVEILSGVFDNITTGTP
IALLIRNEDQRSKDYSKIMDVFRPGHADYTYWQKYGIRDYRGGGRSSARETAVRVAAGAIAKKWLHERYGIVIRGYMAQL
GPIAIPFKNWEVINQNPFFVADDDYVPKLEAFMDALRKSGDSAGARINVIAEGVPVGWGEPVYDRLDADIAYAMMSINAA
KGVEIGAGFNSVTQKGTEHSDEITPEGFLSNNAGGILGGISSSQPITVSVAIKPTSSIRLGRRSIDKAGNPVIVETHGRH
DPCVGIRATPIVEAMLAIVLMDHALRHRGQNEDVVCTTPKVPGNIINPTNPVTTQPDVRRAEDPEPDENS

Sequences:

>Translated_390_residues
MSGNTIGKLFCVTSFGESHGPAIGCIVDGCPPGLVLSAMDIQLELDRRKPGTSRHVTQRHEGDRVEILSGVFDNITTGTP
IALLIRNEDQRSKDYSKIMDVFRPGHADYTYWQKYGIRDYRGGGRSSARETAVRVAAGAIAKKWLHERYGIVIRGYMAQL
GPIAIPFKNWEVINQNPFFVADDDYVPKLEAFMDALRKSGDSAGARINVIAEGVPVGWGEPVYDRLDADIAYAMMSINAA
KGVEIGAGFNSVTQKGTEHSDEITPEGFLSNNAGGILGGISSSQPITVSVAIKPTSSIRLGRRSIDKAGNPVIVETHGRH
DPCVGIRATPIVEAMLAIVLMDHALRHRGQNEDVVCTTPKVPGNIINPTNPVTTQPDVRRAEDPEPDENS
>Mature_389_residues
SGNTIGKLFCVTSFGESHGPAIGCIVDGCPPGLVLSAMDIQLELDRRKPGTSRHVTQRHEGDRVEILSGVFDNITTGTPI
ALLIRNEDQRSKDYSKIMDVFRPGHADYTYWQKYGIRDYRGGGRSSARETAVRVAAGAIAKKWLHERYGIVIRGYMAQLG
PIAIPFKNWEVINQNPFFVADDDYVPKLEAFMDALRKSGDSAGARINVIAEGVPVGWGEPVYDRLDADIAYAMMSINAAK
GVEIGAGFNSVTQKGTEHSDEITPEGFLSNNAGGILGGISSSQPITVSVAIKPTSSIRLGRRSIDKAGNPVIVETHGRHD
PCVGIRATPIVEAMLAIVLMDHALRHRGQNEDVVCTTPKVPGNIINPTNPVTTQPDVRRAEDPEPDENS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=360, Percent_Identity=65.2777777777778, Blast_Score=463, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6321290, Length=368, Percent_Identity=42.1195652173913, Blast_Score=280, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_NITEC (Q0AEP5)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_748152.1
- ProteinModelPortal:   Q0AEP5
- SMR:   Q0AEP5
- STRING:   Q0AEP5
- GeneID:   4273309
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_1957
- NMPDR:   fig|335283.3.peg.1082
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- PhylomeDB:   Q0AEP5
- ProtClustDB:   PRK05382
- BioCyc:   NEUT335283:NEUT_1957-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 42267; Mature: 42136

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNTIGKLFCVTSFGESHGPAIGCIVDGCPPGLVLSAMDIQLELDRRKPGTSRHVTQRH
CCCCCEEEEEEEEECCCCCCCEEEEEECCCCCCEEEEEEEEEEEECCCCCCCCCCHHHHC
EGDRVEILSGVFDNITTGTPIALLIRNEDQRSKDYSKIMDVFRPGHADYTYWQKYGIRDY
CCCHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCC
RGGGRSSARETAVRVAAGAIAKKWLHERYGIVIRGYMAQLGPIAIPFKNWEVINQNPFFV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCEEEECCCCEEECCCCCEE
ADDDYVPKLEAFMDALRKSGDSAGARINVIAEGVPVGWGEPVYDRLDADIAYAMMSINAA
ECCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCC
KGVEIGAGFNSVTQKGTEHSDEITPEGFLSNNAGGILGGISSSQPITVSVAIKPTSSIRL
CCEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCHHH
GRRSIDKAGNPVIVETHGRHDPCVGIRATPIVEAMLAIVLMDHALRHRGQNEDVVCTTPK
CHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
VPGNIINPTNPVTTQPDVRRAEDPEPDENS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SGNTIGKLFCVTSFGESHGPAIGCIVDGCPPGLVLSAMDIQLELDRRKPGTSRHVTQRH
CCCCEEEEEEEEECCCCCCCEEEEEECCCCCCEEEEEEEEEEEECCCCCCCCCCHHHHC
EGDRVEILSGVFDNITTGTPIALLIRNEDQRSKDYSKIMDVFRPGHADYTYWQKYGIRDY
CCCHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCC
RGGGRSSARETAVRVAAGAIAKKWLHERYGIVIRGYMAQLGPIAIPFKNWEVINQNPFFV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCEEEECCCCEEECCCCCEE
ADDDYVPKLEAFMDALRKSGDSAGARINVIAEGVPVGWGEPVYDRLDADIAYAMMSINAA
ECCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCC
KGVEIGAGFNSVTQKGTEHSDEITPEGFLSNNAGGILGGISSSQPITVSVAIKPTSSIRL
CCEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCHHH
GRRSIDKAGNPVIVETHGRHDPCVGIRATPIVEAMLAIVLMDHALRHRGQNEDVVCTTPK
CHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
VPGNIINPTNPVTTQPDVRRAEDPEPDENS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA