Click here to switch to the map view.

The map label for this gene is dsbC [H]

Identifier: 114331672

GI number: 114331672

Start: 1783915

End: 1784628

Strand: Reverse

Name: dsbC [H]

Synonym: Neut_1688

Alternate gene names: 114331672

Gene position: 1784628-1783915 (Counterclockwise)

Preceding gene: 114331673

Following gene: 114331669

Centisome position: 67.06

GC content: 47.76

Gene sequence:

>714_bases
ATGCGTTTGTTTTTATATTCATTCGGCCTGCTGGGATTGTTATTTACTGGAATTGCTCAGGCGAATGAGGCTGATCTGAA
AGAGGCGATTCAGGCTCATTTCCCGGGGAGCAAGATAGAAAGCCTGACGCAGACGCCTTATCTGGGGTTGTATGAGGCCG
TGATCGACGGGGAAATTTTTTATACGGACGAGAAGGCTGAATATTTTTTCATGGGGCATATCGTGGATGCTAAGAAGCGG
GCAAGCTTGACCAGTGAGCGCATGCAGCAGATCCGGGATTCACGGCGGATTGCAATTGACACTTTACCGCTGGAACATGC
GCTGAAAATGGTCAAAGGGAACGGAAAACGTACGCTGATTGTATACTCCGATCCAAATTGCCCTTATTGTAAAAGGCTGG
AGAAGGAGCTGGTTAATGTGACGGATATCACTATTTATACCTTGCTTTATCCTGTTCTTAACGGCTCCATGACAACAGCC
GAAGCCATTTGGTGCTCTGAAGACCGGGTCAAAGCATGGGATGATTTTATGCTGAAATCAGTCGTTCCTACTGGTAAGAA
TTGTGATGCACCGCTGCAGATACTGCTGGAATCAGGCCGTCAGAACAGAGTAACTGGTACACCAACCCTGATTTTTGCAG
ATGGCTCAGTGGTGCCGGGTTTTATCCCGCAATCAGAAATCGAAAAGCGGCTGGATCAGGCCACGAGTAAGTGA

Upstream 100 bases:

>100_bases
GACCAATCGCTTTCCACTTCTGAAAAACAGATTGATGCGTCATGCGCTGAGCTGAATTCGGCTTTTTACGGTTACTGGAT
TTTTATACTGGAGAAATGGT

Downstream 100 bases:

>100_bases
TACAACCTTATCCGCCTGAGTGGCTACCTTCTGAGTCCTTTATTCCCTGTACTGCTTGGGAAGCAGGACCCACATCTGGG
CTTGCTGCTTCATTTTACCC

Product: putative thiol:disulphide interchange protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MRLFLYSFGLLGLLFTGIAQANEADLKEAIQAHFPGSKIESLTQTPYLGLYEAVIDGEIFYTDEKAEYFFMGHIVDAKKR
ASLTSERMQQIRDSRRIAIDTLPLEHALKMVKGNGKRTLIVYSDPNCPYCKRLEKELVNVTDITIYTLLYPVLNGSMTTA
EAIWCSEDRVKAWDDFMLKSVVPTGKNCDAPLQILLESGRQNRVTGTPTLIFADGSVVPGFIPQSEIEKRLDQATSK

Sequences:

>Translated_237_residues
MRLFLYSFGLLGLLFTGIAQANEADLKEAIQAHFPGSKIESLTQTPYLGLYEAVIDGEIFYTDEKAEYFFMGHIVDAKKR
ASLTSERMQQIRDSRRIAIDTLPLEHALKMVKGNGKRTLIVYSDPNCPYCKRLEKELVNVTDITIYTLLYPVLNGSMTTA
EAIWCSEDRVKAWDDFMLKSVVPTGKNCDAPLQILLESGRQNRVTGTPTLIFADGSVVPGFIPQSEIEKRLDQATSK
>Mature_237_residues
MRLFLYSFGLLGLLFTGIAQANEADLKEAIQAHFPGSKIESLTQTPYLGLYEAVIDGEIFYTDEKAEYFFMGHIVDAKKR
ASLTSERMQQIRDSRRIAIDTLPLEHALKMVKGNGKRTLIVYSDPNCPYCKRLEKELVNVTDITIYTLLYPVLNGSMTTA
EAIWCSEDRVKAWDDFMLKSVVPTGKNCDAPLQILLESGRQNRVTGTPTLIFADGSVVPGFIPQSEIEKRLDQATSK

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=239, Percent_Identity=27.1966527196653, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 26593; Mature: 26593

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLFLYSFGLLGLLFTGIAQANEADLKEAIQAHFPGSKIESLTQTPYLGLYEAVIDGEIF
CEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHCCEEE
YTDEKAEYFFMGHIVDAKKRASLTSERMQQIRDSRRIAIDTLPLEHALKMVKGNGKRTLI
EECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCCEEEE
VYSDPNCPYCKRLEKELVNVTDITIYTLLYPVLNGSMTTAEAIWCSEDRVKAWDDFMLKS
EECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHEEECCCCCHHHHHHHHHHH
VVPTGKNCDAPLQILLESGRQNRVTGTPTLIFADGSVVPGFIPQSEIEKRLDQATSK
HCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLFLYSFGLLGLLFTGIAQANEADLKEAIQAHFPGSKIESLTQTPYLGLYEAVIDGEIF
CEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHCCEEE
YTDEKAEYFFMGHIVDAKKRASLTSERMQQIRDSRRIAIDTLPLEHALKMVKGNGKRTLI
EECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCCEEEE
VYSDPNCPYCKRLEKELVNVTDITIYTLLYPVLNGSMTTAEAIWCSEDRVKAWDDFMLKS
EECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHEEECCCCCHHHHHHHHHHH
VVPTGKNCDAPLQILLESGRQNRVTGTPTLIFADGSVVPGFIPQSEIEKRLDQATSK
HCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]