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The map label for this gene is visC [H]

Identifier: 114331673

GI number: 114331673

Start: 1784674

End: 1785840

Strand: Reverse

Name: visC [H]

Synonym: Neut_1689

Alternate gene names: 114331673

Gene position: 1785840-1784674 (Counterclockwise)

Preceding gene: 114331676

Following gene: 114331672

Centisome position: 67.11

GC content: 53.81

Gene sequence:

>1167_bases
ATGAAATTCGATATTGTAGTGATTGGGGGTGGGCTGGTAGGTGCCAGCTTGCTGGCTGCTTTGAAGGATAGCGGGCTGAG
GTTGGCGTTGATTGAATCACGGCCGCCAGCACCTTTGCCAGCTGATGACAGCTGGGATGGGCGTGTGTATGCGATCAGCC
CCGGCAGTGTAGCATTCTTGCATGCTTGTGGGGTCTGGCAGCAGATGGATGCGGCGCGGGTGACGCCTGTCCATGAAATG
CGGGTGCATGGTGACGACAGTGCAGCCAGGATTGATTTCAGTGCGTATGAAAGTGGTGTGCCGGAGCTTGCCTACATCAT
CGAGAATCGCCAGCTGCAGCATGCTGTCTGGGAGACGTTGTCGGAGGCAGAAAATGTGCAGCTGTTTTGTCCGGCGCAAT
ATGACTCACTTACTTGGCATGAATCCTACGTTGAGCTGGCCTTGTCTGATGGCACGGTTTTGCAGACGGCGCTGCTGGTC
GGGGCGGATGGTGTCAATTCCCGCGTGCGTGAACAAGCGGGAATTACGATGGATCGTCATAGCTATTATCAAACCGGGGT
GGTCGCCAATTTTGAGGTGGAGCGGCCTCATCATCACATTGCCTATCAGTGGTTCCGCCGTGATGGCGTTCTTGCACTGC
TGCCGTTGCCGGGAAAACGGGTTTCGATGGTGTGGTCAGCGAATACAGTGCTGGCTGATGAATTGCTTACTTTATCTCCC
GAGGTGTTATGCGAACAGGTTGGACGGGCGGCAGAGCATGAGTTGGGAATGATGCAACTGGTTACGTCGCAACGTGGATT
TCCGCTGAACTTTGTACAAGCCAAATCACTCGTCAAACCGAGGCTGGCTTTGATTGGTGATGCTGCGCATGGGATTCATC
CACTGGCGGGCCAGGGAGTTAATCTGGGATTGCGCGATGCCCGTGAGTTGGCCGATGTTCTTTTGCAGTTTGACGAACTG
GGAGATTGTGGTGAGTTTTCTTTGCTGCGCTGTTACGAACGTAATCGCAAGGAAGATATTCTTGCTATGCAATGGGTGAC
AGATGGGCTGCAGAAACTGTTTGGCAGCGAGGATGCGGCCATTATGCGCATCAGGAATCTGGGGCTCGGGATGACCAATC
GCTTTCCACTTCTGAAAAACAGATTGATGCGTCATGCGCTGAGCTGA

Upstream 100 bases:

>100_bases
ATAAGATTCTTCTGTCTTTTAAAAAAATCTTGTGGGTTTGTTTTCTGCTACGCGCTTGAAAACAATGATCTGGGTGGGGG
TTCCTTAGTATAATCCGACA

Downstream 100 bases:

>100_bases
ATTCGGCTTTTTACGGTTACTGGATTTTTATACTGGAGAAATGGTATGCGTTTGTTTTTATATTCATTCGGCCTGCTGGG
ATTGTTATTTACTGGAATTG

Product: ubiquinone biosynthesis hydroxylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKFDIVVIGGGLVGASLLAALKDSGLRLALIESRPPAPLPADDSWDGRVYAISPGSVAFLHACGVWQQMDAARVTPVHEM
RVHGDDSAARIDFSAYESGVPELAYIIENRQLQHAVWETLSEAENVQLFCPAQYDSLTWHESYVELALSDGTVLQTALLV
GADGVNSRVREQAGITMDRHSYYQTGVVANFEVERPHHHIAYQWFRRDGVLALLPLPGKRVSMVWSANTVLADELLTLSP
EVLCEQVGRAAEHELGMMQLVTSQRGFPLNFVQAKSLVKPRLALIGDAAHGIHPLAGQGVNLGLRDARELADVLLQFDEL
GDCGEFSLLRCYERNRKEDILAMQWVTDGLQKLFGSEDAAIMRIRNLGLGMTNRFPLLKNRLMRHALS

Sequences:

>Translated_388_residues
MKFDIVVIGGGLVGASLLAALKDSGLRLALIESRPPAPLPADDSWDGRVYAISPGSVAFLHACGVWQQMDAARVTPVHEM
RVHGDDSAARIDFSAYESGVPELAYIIENRQLQHAVWETLSEAENVQLFCPAQYDSLTWHESYVELALSDGTVLQTALLV
GADGVNSRVREQAGITMDRHSYYQTGVVANFEVERPHHHIAYQWFRRDGVLALLPLPGKRVSMVWSANTVLADELLTLSP
EVLCEQVGRAAEHELGMMQLVTSQRGFPLNFVQAKSLVKPRLALIGDAAHGIHPLAGQGVNLGLRDARELADVLLQFDEL
GDCGEFSLLRCYERNRKEDILAMQWVTDGLQKLFGSEDAAIMRIRNLGLGMTNRFPLLKNRLMRHALS
>Mature_388_residues
MKFDIVVIGGGLVGASLLAALKDSGLRLALIESRPPAPLPADDSWDGRVYAISPGSVAFLHACGVWQQMDAARVTPVHEM
RVHGDDSAARIDFSAYESGVPELAYIIENRQLQHAVWETLSEAENVQLFCPAQYDSLTWHESYVELALSDGTVLQTALLV
GADGVNSRVREQAGITMDRHSYYQTGVVANFEVERPHHHIAYQWFRRDGVLALLPLPGKRVSMVWSANTVLADELLTLSP
EVLCEQVGRAAEHELGMMQLVTSQRGFPLNFVQAKSLVKPRLALIGDAAHGIHPLAGQGVNLGLRDARELADVLLQFDEL
GDCGEFSLLRCYERNRKEDILAMQWVTDGLQKLFGSEDAAIMRIRNLGLGMTNRFPLLKNRLMRHALS

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=405, Percent_Identity=32.0987654320988, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI32967307, Length=329, Percent_Identity=33.1306990881459, Blast_Score=144, Evalue=1e-34,
Organism=Escherichia coli, GI1789273, Length=386, Percent_Identity=36.0103626943005, Blast_Score=240, Evalue=9e-65,
Organism=Escherichia coli, GI1786883, Length=385, Percent_Identity=35.0649350649351, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1789274, Length=391, Percent_Identity=31.2020460358056, Blast_Score=184, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI25146631, Length=437, Percent_Identity=30.4347826086957, Blast_Score=181, Evalue=5e-46,
Organism=Saccharomyces cerevisiae, GI6321694, Length=460, Percent_Identity=25.2173913043478, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI19920760, Length=428, Percent_Identity=32.2429906542056, Blast_Score=171, Evalue=8e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 42871; Mature: 42871

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFDIVVIGGGLVGASLLAALKDSGLRLALIESRPPAPLPADDSWDGRVYAISPGSVAFL
CEEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCEEEH
HACGVWQQMDAARVTPVHEMRVHGDDSAARIDFSAYESGVPELAYIIENRQLQHAVWETL
HHHCHHHHCCCHHCCCHHHEEEECCCCCEEEEHHHHHCCCCCEEHHHHCCHHHHHHHHHH
SEAENVQLFCPAQYDSLTWHESYVELALSDGTVLQTALLVGADGVNSRVREQAGITMDRH
HCCCCEEEEECCCCCCCCHHHHEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHCCEECCC
SYYQTGVVANFEVERPHHHIAYQWFRRDGVLALLPLPGKRVSMVWSANTVLADELLTLSP
CCCCCCEEEEEEECCCCHHHHHHEECCCCEEEEEECCCCEEEEEEECCHHHHHHHHHCCH
EVLCEQVGRAAEHELGMMQLVTSQRGFPLNFVQAKSLVKPRLALIGDAAHGIHPLAGQGV
HHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHEECCCCCCCCCCCCCC
NLGLRDARELADVLLQFDELGDCGEFSLLRCYERNRKEDILAMQWVTDGLQKLFGSEDAA
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHH
IMRIRNLGLGMTNRFPLLKNRLMRHALS
HHHHHHCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKFDIVVIGGGLVGASLLAALKDSGLRLALIESRPPAPLPADDSWDGRVYAISPGSVAFL
CEEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCEEEH
HACGVWQQMDAARVTPVHEMRVHGDDSAARIDFSAYESGVPELAYIIENRQLQHAVWETL
HHHCHHHHCCCHHCCCHHHEEEECCCCCEEEEHHHHHCCCCCEEHHHHCCHHHHHHHHHH
SEAENVQLFCPAQYDSLTWHESYVELALSDGTVLQTALLVGADGVNSRVREQAGITMDRH
HCCCCEEEEECCCCCCCCHHHHEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHCCEECCC
SYYQTGVVANFEVERPHHHIAYQWFRRDGVLALLPLPGKRVSMVWSANTVLADELLTLSP
CCCCCCEEEEEEECCCCHHHHHHEECCCCEEEEEECCCCEEEEEEECCHHHHHHHHHCCH
EVLCEQVGRAAEHELGMMQLVTSQRGFPLNFVQAKSLVKPRLALIGDAAHGIHPLAGQGV
HHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHEECCCCCCCCCCCCCC
NLGLRDARELADVLLQFDELGDCGEFSLLRCYERNRKEDILAMQWVTDGLQKLFGSEDAA
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHH
IMRIRNLGLGMTNRFPLLKNRLMRHALS
HHHHHHCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]