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The map label for this gene is cheW [H]

Identifier: 114331166

GI number: 114331166

Start: 1216775

End: 1217296

Strand: Direct

Name: cheW [H]

Synonym: Neut_1168

Alternate gene names: 114331166

Gene position: 1216775-1217296 (Clockwise)

Preceding gene: 114331165

Following gene: 114331167

Centisome position: 45.73

GC content: 49.43

Gene sequence:

>522_bases
ATGTTGTTGACACAAGCCACGGCTACTACCACTGCTGCAGGCGAATCACCTGACTCGATCCGGGATCTTTCATGCAGTGA
ATTTCTGATATTCCGGCTGGGAAAAGAGGAATACGGTATCGAGATTCTGAAAGTCCAGGAAATTCGCGGGTATGACGCCA
TTACCCGTATCGCCAACGCACCCGAATTTATCAAGGGCGTTATCAATCTGCGCGGCGTGATCGTGCCGATCGTTGATATG
CGCATCAAATTCAATCTGGGCGCAGCCCATTATGACCAGTTCACTGTGGTGATTATCCTGAATTTGTCCGGGCGAATTAT
CGGCATCGTGGTGGATGGCGTATCCGATGTGATCAACCTGGATACAGAGAATTTGCGCCCTACCCCAGAATTCGGCGGAG
TAATCGATACCGAATACATCATCGGACTTGGCACTATGGAAGAGCGCATGTTGATTCTGGTGGATATCGAAAAATTAATG
AGCAGTTCGGAAATGGGTCTGCTGGAACCGGCAGGCAAATAG

Upstream 100 bases:

>100_bases
CGAAGCAGAGAATGATCCATGCAGCGTAATAAATTGATCAAACCTCTGTGGGAGAAGCCGTTAGAGCCGATACCTATTGC
ACATTACTGAGGAGCAAACC

Downstream 100 bases:

>100_bases
CTTTGTGAATAGTCGCGTGTATTAGTGGCTATGGCGATGAGCACAGTATTTTAAAAGTTAAGTTACTTTATTTATCGGGA
GCAAAAATGTTGCAGAACAT

Product: CheW protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MLLTQATATTTAAGESPDSIRDLSCSEFLIFRLGKEEYGIEILKVQEIRGYDAITRIANAPEFIKGVINLRGVIVPIVDM
RIKFNLGAAHYDQFTVVIILNLSGRIIGIVVDGVSDVINLDTENLRPTPEFGGVIDTEYIIGLGTMEERMLILVDIEKLM
SSSEMGLLEPAGK

Sequences:

>Translated_173_residues
MLLTQATATTTAAGESPDSIRDLSCSEFLIFRLGKEEYGIEILKVQEIRGYDAITRIANAPEFIKGVINLRGVIVPIVDM
RIKFNLGAAHYDQFTVVIILNLSGRIIGIVVDGVSDVINLDTENLRPTPEFGGVIDTEYIIGLGTMEERMLILVDIEKLM
SSSEMGLLEPAGK
>Mature_173_residues
MLLTQATATTTAAGESPDSIRDLSCSEFLIFRLGKEEYGIEILKVQEIRGYDAITRIANAPEFIKGVINLRGVIVPIVDM
RIKFNLGAAHYDQFTVVIILNLSGRIIGIVVDGVSDVINLDTENLRPTPEFGGVIDTEYIIGLGTMEERMLILVDIEKLM
SSSEMGLLEPAGK

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=150, Percent_Identity=64.6666666666667, Blast_Score=198, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 18943; Mature: 18943

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTQATATTTAAGESPDSIRDLSCSEFLIFRLGKEEYGIEILKVQEIRGYDAITRIANA
CEEECCCCCEECCCCCCCHHHCCCCCEEEEEEECCHHHCEEEEEEEECCCHHHHHHHCCC
PEFIKGVINLRGVIVPIVDMRIKFNLGAAHYDQFTVVIILNLSGRIIGIVVDGVSDVINL
HHHHHHHHHHCEEEEEEEEEEEEEECCCCCCCCEEEEEEEECCCEEEEEEECCCHHHEEC
DTENLRPTPEFGGVIDTEYIIGLGTMEERMLILVDIEKLMSSSEMGLLEPAGK
CCCCCCCCCCCCCEECCCEEEEECCCCCCEEEEEEHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MLLTQATATTTAAGESPDSIRDLSCSEFLIFRLGKEEYGIEILKVQEIRGYDAITRIANA
CEEECCCCCEECCCCCCCHHHCCCCCEEEEEEECCHHHCEEEEEEEECCCHHHHHHHCCC
PEFIKGVINLRGVIVPIVDMRIKFNLGAAHYDQFTVVIILNLSGRIIGIVVDGVSDVINL
HHHHHHHHHHCEEEEEEEEEEEEEECCCCCCCCEEEEEEEECCCEEEEEEECCCHHHEEC
DTENLRPTPEFGGVIDTEYIIGLGTMEERMLILVDIEKLMSSSEMGLLEPAGK
CCCCCCCCCCCCCEECCCEEEEECCCCCCEEEEEEHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]