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The map label for this gene is cheA [H]

Identifier: 114331165

GI number: 114331165

Start: 1214568

End: 1216703

Strand: Direct

Name: cheA [H]

Synonym: Neut_1167

Alternate gene names: 114331165

Gene position: 1214568-1216703 (Clockwise)

Preceding gene: 114331161

Following gene: 114331166

Centisome position: 45.64

GC content: 50.28

Gene sequence:

>2136_bases
ATGAGTACTGATCTCGAACAGTTTTATCAGATATTTTTTGAAGAAGCGGGTGAGTTGCTGGCAGAGATGGAAACACGTCT
ACTTAAACTGGATATTTTGTCGCCCAATCCGGAAGATTTGAACGCGATATTTCGTGTGGCGCATTCCATCAAGGGCGGAG
CGGGAACATTCGGGTTTACCGATATGACAGGACTTACGCATGTGCTTGAATCGCTACTCGACAAATTGCGTAAGGATGAA
CTCAAGTTACGCGCTGAAATGGTGGATACCTTTCTGCGTGCTGGGGATGTATTAAAAAATCAACTGGATGGGCACCGGGG
CACTGGTTCCGCCGATCCGGCAGAAGTGGATGCCGTCAACCGCAAACTGAAAGAGTTGGTAGCAGATACGGTTAGCAATA
GCGCAACGTCCGCACCCGAATCGGTAGAGGAATCAGCCCCCCATACAGTGAACACTGCTGAACAGGCCCCAATGTCTGCT
GAATCAGCATCCGTTGCAGGAAATGTCACCACTTACCGGATTGAATTTGGTTGTGCTGATCTTGGCAAGTCAGTAATGGA
GAAGCTGTTAATTGATCTGGCGCGGCAGGGGCAGCTGAAAAACCTGAGTGATCCGGATAACGAAGCAATATGCATATTGC
AGCTTGCCACGACTGACAGTGAGGAAGATGTCTGGGAGGCACTGGCGTTTCTGGTTGATCCCGCCAATTTATCTATCAAA
ATAGATAAAAGCGCATTACCTGCTGCAGATGTTCCCGGAGCAACACTGGAATGCCGACAGGAGCAGCAGACGGTTGAGAC
TGTATCAGAACAACAAGATATGCAGCTTAGTGAAGCTGTATCCTCTCCAACTGCTGCTAATTCAGCCACTCAGAAAACCC
AACTGCCTGCCAAAAAAGCAGTAGCCCCACCGCAACATAAGCCATCCGCTGATCACGCTGGATCCGTTAGCGGTGAATCT
TCTTCCATCCGCGTTGGTGTTGAGAAAGTGGATCAAATGATCAATCTGGTGGGAGAGTTGGTTATCACCCAGGCCATGCT
GGCGCAAACTGCGAGCCAGATCGATCCGGTTATTTTTGAAAAACTGCTCAATGGCCTGAATCAGCTCGAACGAAATACCC
GTGATCTGCAGGAGGCCGTCATGTCGATTCGTATGATGCCCATCAGTTTTGTATTCAGTCGTTTTCCCCGGGTGGTAAGA
GATGTAGCCTCCAAGCTTGGCAAGCAGGTCGATCTCAAAACCCTGGGTGAAGGTACCGAGCTGGATAAAGGATTGATTGA
AAAAATCACTGATCCGTTGACCCATCTGATCCGTAACAGCCTGGATCACGGTATCGAAACACCAGAAAAAAGAAAAGCGC
TGGGTAAACCTGCTCACGGCACGATCACACTGCGTGCATCGCACCAGGGCGGCAGTGTTGTTATAGAGGTGATAGATGAC
GGCGCAGGGCTTAACCGGGAAAAAATTCTGGATAAGGCTCGCAGCCGGGGGTTGGCGATCAGCGAGAACATGACCGATCA
GGATGTCTGGATGCTGATTTTTGAAGCTGGTTTTTCCACGGCAGAAGTTGTGACAGATGTTTCCGGTCGGGGTGTGGGTA
TGGATGTCGTCAAACGCAATATTGAGGGTCTTGGTGGCCGGGTTGAAATTGACTCAATAACCGGGCAAAGAACGAAGATT
TCAATTCGTTTGCCGCTGACGCTCGCTATCCTGGACGGATTATCGGTATCGGTAGGGGATCAGCTGTTTATTATCCCGCT
GACCTATATCACCGAATCACTCAAACCGGCTGCAGAAGATATCCGCACCATACGAGGCCAGGGTCGGGTGGTGGAGGTGC
GCGGCGAGTACCTGCCGGTGATTGCTCTGCATGAAATTTTCGGCCTGGAACCGGAAGTGCATGAGATCCATGAAGGCATT
CTGGTCATCCTTGATGCTGAAGGAAACAAGGCCGCCATGTTTGTCGATACGCTGGTTGGGCAACACCAGGTGGTGATCAA
AAGTCTGGAAAGCAATTATCGTCGCGTACAGGGCGTTTCAGGCGCAACCATCATGGGTGATGGTAGTGTTGCTCTGATAC
TGGATGCTGTGGGGCTGGTCAATGTCACGAAGCAGAGAATGATCCATGCAGCGTAA

Upstream 100 bases:

>100_bases
CTGCAGAACAGGTGGAAATGAAAGCAGTTTATACGTTTGTTCGAAACTACTGGCTTGTTTTGCTGCGGTAAGCTGTTGCA
AATTTCAGACAGGAGTCCTC

Downstream 100 bases:

>100_bases
TAAATTGATCAAACCTCTGTGGGAGAAGCCGTTAGAGCCGATACCTATTGCACATTACTGAGGAGCAAACCATGTTGTTG
ACACAAGCCACGGCTACTAC

Product: CheA signal transduction histidine kinases

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 711; Mature: 710

Protein sequence:

>711_residues
MSTDLEQFYQIFFEEAGELLAEMETRLLKLDILSPNPEDLNAIFRVAHSIKGGAGTFGFTDMTGLTHVLESLLDKLRKDE
LKLRAEMVDTFLRAGDVLKNQLDGHRGTGSADPAEVDAVNRKLKELVADTVSNSATSAPESVEESAPHTVNTAEQAPMSA
ESASVAGNVTTYRIEFGCADLGKSVMEKLLIDLARQGQLKNLSDPDNEAICILQLATTDSEEDVWEALAFLVDPANLSIK
IDKSALPAADVPGATLECRQEQQTVETVSEQQDMQLSEAVSSPTAANSATQKTQLPAKKAVAPPQHKPSADHAGSVSGES
SSIRVGVEKVDQMINLVGELVITQAMLAQTASQIDPVIFEKLLNGLNQLERNTRDLQEAVMSIRMMPISFVFSRFPRVVR
DVASKLGKQVDLKTLGEGTELDKGLIEKITDPLTHLIRNSLDHGIETPEKRKALGKPAHGTITLRASHQGGSVVIEVIDD
GAGLNREKILDKARSRGLAISENMTDQDVWMLIFEAGFSTAEVVTDVSGRGVGMDVVKRNIEGLGGRVEIDSITGQRTKI
SIRLPLTLAILDGLSVSVGDQLFIIPLTYITESLKPAAEDIRTIRGQGRVVEVRGEYLPVIALHEIFGLEPEVHEIHEGI
LVILDAEGNKAAMFVDTLVGQHQVVIKSLESNYRRVQGVSGATIMGDGSVALILDAVGLVNVTKQRMIHAA

Sequences:

>Translated_711_residues
MSTDLEQFYQIFFEEAGELLAEMETRLLKLDILSPNPEDLNAIFRVAHSIKGGAGTFGFTDMTGLTHVLESLLDKLRKDE
LKLRAEMVDTFLRAGDVLKNQLDGHRGTGSADPAEVDAVNRKLKELVADTVSNSATSAPESVEESAPHTVNTAEQAPMSA
ESASVAGNVTTYRIEFGCADLGKSVMEKLLIDLARQGQLKNLSDPDNEAICILQLATTDSEEDVWEALAFLVDPANLSIK
IDKSALPAADVPGATLECRQEQQTVETVSEQQDMQLSEAVSSPTAANSATQKTQLPAKKAVAPPQHKPSADHAGSVSGES
SSIRVGVEKVDQMINLVGELVITQAMLAQTASQIDPVIFEKLLNGLNQLERNTRDLQEAVMSIRMMPISFVFSRFPRVVR
DVASKLGKQVDLKTLGEGTELDKGLIEKITDPLTHLIRNSLDHGIETPEKRKALGKPAHGTITLRASHQGGSVVIEVIDD
GAGLNREKILDKARSRGLAISENMTDQDVWMLIFEAGFSTAEVVTDVSGRGVGMDVVKRNIEGLGGRVEIDSITGQRTKI
SIRLPLTLAILDGLSVSVGDQLFIIPLTYITESLKPAAEDIRTIRGQGRVVEVRGEYLPVIALHEIFGLEPEVHEIHEGI
LVILDAEGNKAAMFVDTLVGQHQVVIKSLESNYRRVQGVSGATIMGDGSVALILDAVGLVNVTKQRMIHAA
>Mature_710_residues
STDLEQFYQIFFEEAGELLAEMETRLLKLDILSPNPEDLNAIFRVAHSIKGGAGTFGFTDMTGLTHVLESLLDKLRKDEL
KLRAEMVDTFLRAGDVLKNQLDGHRGTGSADPAEVDAVNRKLKELVADTVSNSATSAPESVEESAPHTVNTAEQAPMSAE
SASVAGNVTTYRIEFGCADLGKSVMEKLLIDLARQGQLKNLSDPDNEAICILQLATTDSEEDVWEALAFLVDPANLSIKI
DKSALPAADVPGATLECRQEQQTVETVSEQQDMQLSEAVSSPTAANSATQKTQLPAKKAVAPPQHKPSADHAGSVSGESS
SIRVGVEKVDQMINLVGELVITQAMLAQTASQIDPVIFEKLLNGLNQLERNTRDLQEAVMSIRMMPISFVFSRFPRVVRD
VASKLGKQVDLKTLGEGTELDKGLIEKITDPLTHLIRNSLDHGIETPEKRKALGKPAHGTITLRASHQGGSVVIEVIDDG
AGLNREKILDKARSRGLAISENMTDQDVWMLIFEAGFSTAEVVTDVSGRGVGMDVVKRNIEGLGGRVEIDSITGQRTKIS
IRLPLTLAILDGLSVSVGDQLFIIPLTYITESLKPAAEDIRTIRGQGRVVEVRGEYLPVIALHEIFGLEPEVHEIHEGIL
VILDAEGNKAAMFVDTLVGQHQVVIKSLESNYRRVQGVSGATIMGDGSVALILDAVGLVNVTKQRMIHAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=715, Percent_Identity=48.1118881118881, Blast_Score=613, Evalue=1e-177,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76824; Mature: 76692

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDLEQFYQIFFEEAGELLAEMETRLLKLDILSPNPEDLNAIFRVAHSIKGGAGTFGFT
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCH
DMTGLTHVLESLLDKLRKDELKLRAEMVDTFLRAGDVLKNQLDGHRGTGSADPAEVDAVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
RKLKELVADTVSNSATSAPESVEESAPHTVNTAEQAPMSAESASVAGNVTTYRIEFGCAD
HHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEEECHHH
LGKSVMEKLLIDLARQGQLKNLSDPDNEAICILQLATTDSEEDVWEALAFLVDPANLSIK
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCEEE
IDKSALPAADVPGATLECRQEQQTVETVSEQQDMQLSEAVSSPTAANSATQKTQLPAKKA
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHC
VAPPQHKPSADHAGSVSGESSSIRVGVEKVDQMINLVGELVITQAMLAQTASQIDPVIFE
CCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KLLNGLNQLERNTRDLQEAVMSIRMMPISFVFSRFPRVVRDVASKLGKQVDLKTLGEGTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCH
LDKGLIEKITDPLTHLIRNSLDHGIETPEKRKALGKPAHGTITLRASHQGGSVVIEVIDD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEEEECCCCEEEEEEECC
GAGLNREKILDKARSRGLAISENMTDQDVWMLIFEAGFSTAEVVTDVSGRGVGMDVVKRN
CCCCCHHHHHHHHHHCCEEEECCCCCCHHEEEHHHCCCCHHHHHHCCCCCCCCHHHHHHH
IEGLGGRVEIDSITGQRTKISIRLPLTLAILDGLSVSVGDQLFIIPLTYITESLKPAAED
HHCCCCEEEEECCCCCEEEEEEECCEEEEHHCCCEECCCCEEEEEEHHHHHHHCCHHHHH
IRTIRGQGRVVEVRGEYLPVIALHEIFGLEPEVHEIHEGILVILDAEGNKAAMFVDTLVG
HHHHHCCCCEEEECCCEECHHHHHHHHCCCCHHHHHCCCEEEEEECCCCCEEEHHHHHHC
QHQVVIKSLESNYRRVQGVSGATIMGDGSVALILDAVGLVNVTKQRMIHAA
CHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STDLEQFYQIFFEEAGELLAEMETRLLKLDILSPNPEDLNAIFRVAHSIKGGAGTFGFT
CCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCH
DMTGLTHVLESLLDKLRKDELKLRAEMVDTFLRAGDVLKNQLDGHRGTGSADPAEVDAVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
RKLKELVADTVSNSATSAPESVEESAPHTVNTAEQAPMSAESASVAGNVTTYRIEFGCAD
HHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEEECHHH
LGKSVMEKLLIDLARQGQLKNLSDPDNEAICILQLATTDSEEDVWEALAFLVDPANLSIK
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCEEE
IDKSALPAADVPGATLECRQEQQTVETVSEQQDMQLSEAVSSPTAANSATQKTQLPAKKA
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHC
VAPPQHKPSADHAGSVSGESSSIRVGVEKVDQMINLVGELVITQAMLAQTASQIDPVIFE
CCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KLLNGLNQLERNTRDLQEAVMSIRMMPISFVFSRFPRVVRDVASKLGKQVDLKTLGEGTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCH
LDKGLIEKITDPLTHLIRNSLDHGIETPEKRKALGKPAHGTITLRASHQGGSVVIEVIDD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEEEECCCCEEEEEEECC
GAGLNREKILDKARSRGLAISENMTDQDVWMLIFEAGFSTAEVVTDVSGRGVGMDVVKRN
CCCCCHHHHHHHHHHCCEEEECCCCCCHHEEEHHHCCCCHHHHHHCCCCCCCCHHHHHHH
IEGLGGRVEIDSITGQRTKISIRLPLTLAILDGLSVSVGDQLFIIPLTYITESLKPAAED
HHCCCCEEEEECCCCCEEEEEEECCEEEEHHCCCEECCCCEEEEEEHHHHHHHCCHHHHH
IRTIRGQGRVVEVRGEYLPVIALHEIFGLEPEVHEIHEGILVILDAEGNKAAMFVDTLVG
HHHHHCCCCEEEECCCEECHHHHHHHHCCCCHHHHHCCCEEEEEECCCCCEEEHHHHHHC
QHQVVIKSLESNYRRVQGVSGATIMGDGSVALILDAVGLVNVTKQRMIHAA
CHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2002011; 9097040; 9278503; 3510184; 2832069; 2068106; 8555213; 8639521; 9020767; 9437425; 9636149 [H]