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The map label for this gene is ubiA [H]

Identifier: 114331126

GI number: 114331126

Start: 1168147

End: 1169007

Strand: Reverse

Name: ubiA [H]

Synonym: Neut_1128

Alternate gene names: 114331126

Gene position: 1169007-1168147 (Counterclockwise)

Preceding gene: 114331127

Following gene: 114331125

Centisome position: 43.93

GC content: 50.41

Gene sequence:

>861_bases
ATGACTTTCAGTGAACGATTTTCTGCATACGCCAGGCTGACCCGGCTGGATAAACCAATTGGCATCCTGCTACTGCTGTG
GCCAACATTGTGGGGGCTGTGGCTAGCAGCCGATGGTATGCCGGATCCAATGATTCTGGTAATCTTTGTGCTCGGCACGA
TCCTGATGCGCTCTGCTGGTTGTGCTATCAATGATTTTGCCGATCGAAAGATCGATCCTCATGTTTCTCGAACCCGTAAC
CGCCCACTGGCAACTGGCATCATCAGCTCTCGCGAAGCGCTGCTAGTTGCTGCTGGGCTAAGTTTGTGCGCCTTTTTACT
AATTCTACCGCTCAATCTCCTGACAATCCTGCTATCCGTACCCGCCCTGCTCCTTGCCATCTCCTATCCGTTTACCAAAC
GCTTTTTTGCCATGCCTCAAGCGTACCTCGGCATAGCGTTCAGCTTTGGCATTCCCATGGCATTTGCGGCACAAACGGGA
ACTGTTCCACCGCTTGCGTGGCTACTGGTATTGGCCAATCTGTTCTGGGTTATTGCTTACGACACCGAATATGCACTGGT
AGATCTGGCAGACGATCTAAAAATTGGCATCAAAACTTCTGCCATTACGTTTGGACGGTTTGATGTGGCGGGTATTCTGC
TGTGCCACATTACCTTCCTGAGTATTCTGACTTATGCGGGAATATTGCTGCAGCGCGGTATCTGGTTTTATGGCGCCTTA
CTGGTGGCATTGGGCCTGGTTATCGTTCAATACACCATGATCCGCAACCGTGAACCTGCCCGTTGTTTCCAGGCATTTTT
GCATAACAACCGGGTTGGAGCAGTCATATTCGCGGGTATATTGCTGGATACACTGATTTGA

Upstream 100 bases:

>100_bases
GCCTGCAATCCACCAACTATAAATCGATAAAATACTCTATCCCGGCCGGCTCAAACAGGCTGGAATACTTTACTGACCTG
GTTTTTATGACTTTTATAAT

Downstream 100 bases:

>100_bases
GTTGATCAACCAATCTCACCACGAATCTGGCTCAATGCTGCGCTGCACCAGCGTACTCTGTTTAATTCATTCACAAAAAC
TGGATCTGTTTTATGAAATA

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MTFSERFSAYARLTRLDKPIGILLLLWPTLWGLWLAADGMPDPMILVIFVLGTILMRSAGCAINDFADRKIDPHVSRTRN
RPLATGIISSREALLVAAGLSLCAFLLILPLNLLTILLSVPALLLAISYPFTKRFFAMPQAYLGIAFSFGIPMAFAAQTG
TVPPLAWLLVLANLFWVIAYDTEYALVDLADDLKIGIKTSAITFGRFDVAGILLCHITFLSILTYAGILLQRGIWFYGAL
LVALGLVIVQYTMIRNREPARCFQAFLHNNRVGAVIFAGILLDTLI

Sequences:

>Translated_286_residues
MTFSERFSAYARLTRLDKPIGILLLLWPTLWGLWLAADGMPDPMILVIFVLGTILMRSAGCAINDFADRKIDPHVSRTRN
RPLATGIISSREALLVAAGLSLCAFLLILPLNLLTILLSVPALLLAISYPFTKRFFAMPQAYLGIAFSFGIPMAFAAQTG
TVPPLAWLLVLANLFWVIAYDTEYALVDLADDLKIGIKTSAITFGRFDVAGILLCHITFLSILTYAGILLQRGIWFYGAL
LVALGLVIVQYTMIRNREPARCFQAFLHNNRVGAVIFAGILLDTLI
>Mature_285_residues
TFSERFSAYARLTRLDKPIGILLLLWPTLWGLWLAADGMPDPMILVIFVLGTILMRSAGCAINDFADRKIDPHVSRTRNR
PLATGIISSREALLVAAGLSLCAFLLILPLNLLTILLSVPALLLAISYPFTKRFFAMPQAYLGIAFSFGIPMAFAAQTGT
VPPLAWLLVLANLFWVIAYDTEYALVDLADDLKIGIKTSAITFGRFDVAGILLCHITFLSILTYAGILLQRGIWFYGALL
VALGLVIVQYTMIRNREPARCFQAFLHNNRVGAVIFAGILLDTLI

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=279, Percent_Identity=36.5591397849462, Blast_Score=162, Evalue=2e-40,
Organism=Escherichia coli, GI1790473, Length=277, Percent_Identity=51.2635379061372, Blast_Score=264, Evalue=5e-72,
Organism=Caenorhabditis elegans, GI17553718, Length=281, Percent_Identity=34.1637010676157, Blast_Score=150, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI32565247, Length=281, Percent_Identity=32.7402135231317, Blast_Score=137, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17553720, Length=337, Percent_Identity=28.7833827893175, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32565245, Length=137, Percent_Identity=40.8759124087591, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32565243, Length=133, Percent_Identity=40.6015037593985, Blast_Score=95, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6324370, Length=278, Percent_Identity=31.6546762589928, Blast_Score=126, Evalue=5e-30,
Organism=Drosophila melanogaster, GI21355567, Length=281, Percent_Identity=39.8576512455516, Blast_Score=183, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 31507; Mature: 31376

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFSERFSAYARLTRLDKPIGILLLLWPTLWGLWLAADGMPDPMILVIFVLGTILMRSAG
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
CAINDFADRKIDPHVSRTRNRPLATGIISSREALLVAAGLSLCAFLLILPLNLLTILLSV
CCHHHHHCCCCCCCHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PALLLAISYPFTKRFFAMPQAYLGIAFSFGIPMAFAAQTGTVPPLAWLLVLANLFWVIAY
HHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHEEEE
DTEYALVDLADDLKIGIKTSAITFGRFDVAGILLCHITFLSILTYAGILLQRGIWFYGAL
CCCEEEEECCCCHHCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVALGLVIVQYTMIRNREPARCFQAFLHNNRVGAVIFAGILLDTLI
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TFSERFSAYARLTRLDKPIGILLLLWPTLWGLWLAADGMPDPMILVIFVLGTILMRSAG
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
CAINDFADRKIDPHVSRTRNRPLATGIISSREALLVAAGLSLCAFLLILPLNLLTILLSV
CCHHHHHCCCCCCCHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PALLLAISYPFTKRFFAMPQAYLGIAFSFGIPMAFAAQTGTVPPLAWLLVLANLFWVIAY
HHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHEEEE
DTEYALVDLADDLKIGIKTSAITFGRFDVAGILLCHITFLSILTYAGILLQRGIWFYGAL
CCCEEEEECCCCHHCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVALGLVIVQYTMIRNREPARCFQAFLHNNRVGAVIFAGILLDTLI
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]