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The map label for this gene is ubiC

Identifier: 114331127

GI number: 114331127

Start: 1169086

End: 1169550

Strand: Reverse

Name: ubiC

Synonym: Neut_1129

Alternate gene names: 114331127

Gene position: 1169550-1169086 (Counterclockwise)

Preceding gene: 114331128

Following gene: 114331126

Centisome position: 43.95

GC content: 47.96

Gene sequence:

>465_bases
ATGCACCAGGAATCCCTCACTCGCCTGCTTCAGGCACATTGTGAGCATTTCCGTGTTGAACCTGTTTTTCAGACACTGGC
AACGGCATGCATCGACGAACTGGAAGTCATGAATCTGCGCAGACAAAATCAGGTATTGGTACGGGAAGTTTACCTGCGTT
GTAATGAAACACCGGTTGTATTTGCCCATTCGATCGTTAAAAAAGAACATTTACGAGGAGCATGGCGCGGGTTAAGCCGT
TTGGGTAATCGATCATTGGGCACTATGTTGTTTACCAACCCGCTAATACAGCGCACTCCTCTTGCCTTCAAGAAACTGAA
ACCGCACCACCCATTATTCGAGCGTGCCTGCAAACAACTGCAGATGCGCCCAATCAATCTCTGGGCAAGGCGCTCGTTAT
TTATCCTATTGCGGCAGCCGATACTCGTTACAGAAGTATTTCTGCCTGCAATCCACCAACTATAA

Upstream 100 bases:

>100_bases
TTTCCCCGTTTTCCATACTCTTGTCGTAATGAAGGCCAACCCGCCTCTGGCGTGGCATCCTGTCCCTGTTTCCGCTCCTG
TTAATCTCCGCTGGTGGCTG

Downstream 100 bases:

>100_bases
ATCGATAAAATACTCTATCCCGGCCGGCTCAAACAGGCTGGAATACTTTACTGACCTGGTTTTTATGACTTTTATAATAT
GACTTTCAGTGAACGATTTT

Product: chorismate lyase

Products: NA

Alternate protein names: CL; CPL

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MHQESLTRLLQAHCEHFRVEPVFQTLATACIDELEVMNLRRQNQVLVREVYLRCNETPVVFAHSIVKKEHLRGAWRGLSR
LGNRSLGTMLFTNPLIQRTPLAFKKLKPHHPLFERACKQLQMRPINLWARRSLFILLRQPILVTEVFLPAIHQL

Sequences:

>Translated_154_residues
MHQESLTRLLQAHCEHFRVEPVFQTLATACIDELEVMNLRRQNQVLVREVYLRCNETPVVFAHSIVKKEHLRGAWRGLSR
LGNRSLGTMLFTNPLIQRTPLAFKKLKPHHPLFERACKQLQMRPINLWARRSLFILLRQPILVTEVFLPAIHQL
>Mature_154_residues
MHQESLTRLLQAHCEHFRVEPVFQTLATACIDELEVMNLRRQNQVLVREVYLRCNETPVVFAHSIVKKEHLRGAWRGLSR
LGNRSLGTMLFTNPLIQRTPLAFKKLKPHHPLFERACKQLQMRPINLWARRSLFILLRQPILVTEVFLPAIHQL

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIC_NITEC (Q0AGZ8)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_747349.1
- ProteinModelPortal:   Q0AGZ8
- SMR:   Q0AGZ8
- STRING:   Q0AGZ8
- GeneID:   4272411
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_1129
- NMPDR:   fig|335283.3.peg.988
- eggNOG:   COG3161
- HOGENOM:   HBG644467
- ProtClustDB:   CLSK585969
- BioCyc:   NEUT335283:NEUT_1129-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01632
- InterPro:   IPR007440

Pfam domain/function: PF04345 Chor_lyase

EC number: =4.1.3.40

Molecular weight: Translated: 18104; Mature: 18104

Theoretical pI: Translated: 11.21; Mature: 11.21

Prosite motif: NA

Important sites: BINDING 72-72 BINDING 110-110

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQESLTRLLQAHCEHFRVEPVFQTLATACIDELEVMNLRRQNQVLVREVYLRCNETPVV
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
FAHSIVKKEHLRGAWRGLSRLGNRSLGTMLFTNPLIQRTPLAFKKLKPHHPLFERACKQL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHCCHHHHHCCCCCHHHHHHHHHH
QMRPINLWARRSLFILLRQPILVTEVFLPAIHQL
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHQESLTRLLQAHCEHFRVEPVFQTLATACIDELEVMNLRRQNQVLVREVYLRCNETPVV
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
FAHSIVKKEHLRGAWRGLSRLGNRSLGTMLFTNPLIQRTPLAFKKLKPHHPLFERACKQL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHCCHHHHHCCCCCHHHHHHHHHH
QMRPINLWARRSLFILLRQPILVTEVFLPAIHQL
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA