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The map label for this gene is grx [H]

Identifier: 114330672

GI number: 114330672

Start: 666998

End: 667285

Strand: Direct

Name: grx [H]

Synonym: Neut_0657

Alternate gene names: 114330672

Gene position: 666998-667285 (Clockwise)

Preceding gene: 114330671

Following gene: 114330673

Centisome position: 25.07

GC content: 52.08

Gene sequence:

>288_bases
ATGGATGATAACGGCGCGGAAAGAGACAAAATGCCCAAGGTAGTGATGTATGTATCCGGATTTTGCCCCTATTGCACCAT
GGCAGAAAAATTGTTGCGTGCAAGAGGCGTGGAGGAGATTGAGAAGATCAGAGTGGATCTGCAACCAGGGCAACGAACCG
AGATGATGCGGCGTTCCGGACGACGAACGGTTCCGCAGATCTATATTGGACAGACCCATGTTGGAGGGTATGACGATTTG
TCAATGCTGGATCGACAGGGTGAGCTGGCCAGTCTGCTGGCTGGCTGA

Upstream 100 bases:

>100_bases
CTGGTTCCGTTTTGCGCAAAAATGGTTTTAAACAGGTTTTTAATCTATCTGGTGGCATTGAAACCTGGCAGCGTGAGAAT
CTTCCATTGGTGAAAAAGTG

Downstream 100 bases:

>100_bases
ATGTCTGCCGGTATCTGATTGTTATTGGAAGCTGACTTATTTATTTTGATAAATGTATTTAACCGGAATCAACCATGACT
GAACCACAGCAGCAGCCCGT

Product: glutaredoxin 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 95; Mature: 95

Protein sequence:

>95_residues
MDDNGAERDKMPKVVMYVSGFCPYCTMAEKLLRARGVEEIEKIRVDLQPGQRTEMMRRSGRRTVPQIYIGQTHVGGYDDL
SMLDRQGELASLLAG

Sequences:

>Translated_95_residues
MDDNGAERDKMPKVVMYVSGFCPYCTMAEKLLRARGVEEIEKIRVDLQPGQRTEMMRRSGRRTVPQIYIGQTHVGGYDDL
SMLDRQGELASLLAG
>Mature_95_residues
MDDNGAERDKMPKVVMYVSGFCPYCTMAEKLLRARGVEEIEKIRVDLQPGQRTEMMRRSGRRTVPQIYIGQTHVGGYDDL
SMLDRQGELASLLAG

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=83, Percent_Identity=45.7831325301205, Blast_Score=77, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 10738; Mature: 10738

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
7.4 %Met     (Translated Protein)
9.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
7.4 %Met     (Mature Protein)
9.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDNGAERDKMPKVVMYVSGFCPYCTMAEKLLRARGVEEIEKIRVDLQPGQRTEMMRRSG
CCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHCC
RRTVPQIYIGQTHVGGYDDLSMLDRQGELASLLAG
CCCCCEEECCCCCCCCCCCHHHHHCCCHHHHHHCC
>Mature Secondary Structure
MDDNGAERDKMPKVVMYVSGFCPYCTMAEKLLRARGVEEIEKIRVDLQPGQRTEMMRRSG
CCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHCC
RRTVPQIYIGQTHVGGYDDLSMLDRQGELASLLAG
CCCCCEEECCCCCCCCCCCHHHHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]