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The map label for this gene is mpg1 [H]

Identifier: 114330190

GI number: 114330190

Start: 162836

End: 163522

Strand: Direct

Name: mpg1 [H]

Synonym: Neut_0159

Alternate gene names: 114330190

Gene position: 162836-163522 (Clockwise)

Preceding gene: 114330189

Following gene: 114330191

Centisome position: 6.12

GC content: 51.97

Gene sequence:

>687_bases
ATGGAAGCCATTATTCTGGCTGGGGGGCTGGGCACGCGCTTACGCAAGGTTGTGGCCGATGTACCCAAGCCCATGGCGCC
TATTGCGGGTCGTCCATTTCTGGAAATTCTGCTTGATGTGCTGGCACGTAAAGGTTTCAAGCGGATCATCCTCTCGGTAG
GATTCATGGCAGAGAAGGTCAGTAGCTATTTTGGCTCGCTTCATGCAGGTATGGATTTGATTTATGTGATGGAAGATCAA
CCGCTTGGTACAGGCGGTGGGGTACGTCTGTCGCTTGAACAGGTGGTTTCTGACCATGTGTTTGTGTTTAACGGAGATAC
ATTTCTGGATCTGGAAATCGATCAGGTGGAACAGCAATGGCAATCCAGGCGGCACCCGATTATTGTAGGACGGGCGGTGG
CGGATACATCGCGTTATGGTCGTTTGCTTGTAAGTGATGGTGTGGTCCAGGGATTTGCCGGGAAAGATACCGCCGGGCCC
GGACTGATCAACGCCGGGTGTTATGTATTCAAACGCCAACAACTGGATGATTTTCCTGCCGATCAACCTTTCTCACTGGA
GTCTGATTTTCTTGCTCCGGCTGTGGCGCGTGGAGAATTTGATGTATTCGTCACGGCAGGGAAGTTCATCGATATTGGAG
TGCCAGAGGATTTCCTGCGCGCGCAGACTGAACTGGCCGGATTTTGA

Upstream 100 bases:

>100_bases
TTCCGTCGGCGGATACGCCGAAGATTCAGGAAGGTCACGCCGTACTGGGCCATATCCTCTGTGGTTTGGTGGAGCGTACG
CTGTTCAAGGCTCCCATTTG

Downstream 100 bases:

>100_bases
TCCGTGACCAATGCAGCACTATTCCTGGATCGTGATGGAGTGATCAATATCGACCACGGGTATGTTTATCAGTCTCAGAA
TTTTGAATTCGTGCCGGATA

Product: nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MEAIILAGGLGTRLRKVVADVPKPMAPIAGRPFLEILLDVLARKGFKRIILSVGFMAEKVSSYFGSLHAGMDLIYVMEDQ
PLGTGGGVRLSLEQVVSDHVFVFNGDTFLDLEIDQVEQQWQSRRHPIIVGRAVADTSRYGRLLVSDGVVQGFAGKDTAGP
GLINAGCYVFKRQQLDDFPADQPFSLESDFLAPAVARGEFDVFVTAGKFIDIGVPEDFLRAQTELAGF

Sequences:

>Translated_228_residues
MEAIILAGGLGTRLRKVVADVPKPMAPIAGRPFLEILLDVLARKGFKRIILSVGFMAEKVSSYFGSLHAGMDLIYVMEDQ
PLGTGGGVRLSLEQVVSDHVFVFNGDTFLDLEIDQVEQQWQSRRHPIIVGRAVADTSRYGRLLVSDGVVQGFAGKDTAGP
GLINAGCYVFKRQQLDDFPADQPFSLESDFLAPAVARGEFDVFVTAGKFIDIGVPEDFLRAQTELAGF
>Mature_228_residues
MEAIILAGGLGTRLRKVVADVPKPMAPIAGRPFLEILLDVLARKGFKRIILSVGFMAEKVSSYFGSLHAGMDLIYVMEDQ
PLGTGGGVRLSLEQVVSDHVFVFNGDTFLDLEIDQVEQQWQSRRHPIIVGRAVADTSRYGRLLVSDGVVQGFAGKDTAGP
GLINAGCYVFKRQQLDDFPADQPFSLESDFLAPAVARGEFDVFVTAGKFIDIGVPEDFLRAQTELAGF

Specific function: Unknown

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761619, Length=233, Percent_Identity=30.0429184549356, Blast_Score=87, Evalue=8e-18,
Organism=Homo sapiens, GI11761621, Length=233, Percent_Identity=30.0429184549356, Blast_Score=87, Evalue=9e-18,
Organism=Homo sapiens, GI31881779, Length=247, Percent_Identity=26.3157894736842, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI45447090, Length=247, Percent_Identity=26.3157894736842, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI133931050, Length=231, Percent_Identity=32.4675324675325, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6320148, Length=230, Percent_Identity=28.2608695652174, Blast_Score=88, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21355443, Length=224, Percent_Identity=32.1428571428571, Blast_Score=103, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24644084, Length=224, Percent_Identity=32.1428571428571, Blast_Score=103, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24653912, Length=188, Percent_Identity=28.7234042553192, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 24807; Mature: 24807

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAIILAGGLGTRLRKVVADVPKPMAPIAGRPFLEILLDVLARKGFKRIILSVGFMAEKV
CCEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
SSYFGSLHAGMDLIYVMEDQPLGTGGGVRLSLEQVVSDHVFVFNGDTFLDLEIDQVEQQW
HHHHHHHHCCCEEEEEEECCCCCCCCCEEEEHHHHHHCCEEEEECCEEEEEEHHHHHHHH
QSRRHPIIVGRAVADTSRYGRLLVSDGVVQGFAGKDTAGPGLINAGCYVFKRQQLDDFPA
HHCCCCEEEEEHHHHHHHHCEEEEECCEEECCCCCCCCCCCEEECCCCEEECCCCCCCCC
DQPFSLESDFLAPAVARGEFDVFVTAGKFIDIGVPEDFLRAQTELAGF
CCCCCCCCCHHCHHHHCCCEEEEEEECCEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MEAIILAGGLGTRLRKVVADVPKPMAPIAGRPFLEILLDVLARKGFKRIILSVGFMAEKV
CCEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
SSYFGSLHAGMDLIYVMEDQPLGTGGGVRLSLEQVVSDHVFVFNGDTFLDLEIDQVEQQW
HHHHHHHHCCCEEEEEEECCCCCCCCCEEEEHHHHHHCCEEEEECCEEEEEEHHHHHHHH
QSRRHPIIVGRAVADTSRYGRLLVSDGVVQGFAGKDTAGPGLINAGCYVFKRQQLDDFPA
HHCCCCEEEEEHHHHHHHHCEEEEECCEEECCCCCCCCCCCEEECCCCEEECCCCCCCCC
DQPFSLESDFLAPAVARGEFDVFVTAGKFIDIGVPEDFLRAQTELAGF
CCCCCCCCCHHCHHHHCCCEEEEEEECCEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]