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The map label for this gene is gmhB [H]

Identifier: 114330191

GI number: 114330191

Start: 163526

End: 164083

Strand: Direct

Name: gmhB [H]

Synonym: Neut_0160

Alternate gene names: 114330191

Gene position: 163526-164083 (Clockwise)

Preceding gene: 114330190

Following gene: 114330192

Centisome position: 6.15

GC content: 45.88

Gene sequence:

>558_bases
GTGACCAATGCAGCACTATTCCTGGATCGTGATGGAGTGATCAATATCGACCACGGGTATGTTTATCAGTCTCAGAATTT
TGAATTCGTGCCGGATATATTTGATCTGGTTCGTACAGCACGTAATCTGGACTACAAGATAATTGTCATCACTAATCAGG
CCGGGATTGGTCGGGGTTACTATACCGAGGCGCAGTTTCATACGCTTACACAATGGATGCGACAGCGCTTTGAAGATCAA
AATGCAAGCATCGATGCCGTTTATTTTTGCCCCTTCCACCCCGAGCATGGCGTGGGCTATTACCGGCAAGAGAGTGAGTT
TCGCAAGCCTAATCCGGGTATGTTCTTTCAAGCAGCACGTGAGCACGGGTTGGATTTGGATCGGTGCGTGCTTGTTGGTG
ACAAGATCAGTGATATTGAAGCGGCCGCCGCTGCTGGTATTCCTGTGCGTTTTTTATTTCGTTCTACAGATTCTTGTCAT
GCAGCCATTTCCATATCGGAATTGGTAGAAGTGGAACAATTTCTTTTGAAAAATTTACTCGAACCTGATAAGCAATGA

Upstream 100 bases:

>100_bases
TGGAGAATTTGATGTATTCGTCACGGCAGGGAAGTTCATCGATATTGGAGTGCCAGAGGATTTCCTGCGCGCGCAGACTG
AACTGGCCGGATTTTGATCC

Downstream 100 bases:

>100_bases
TTCCAGTATTATGGAGATTTTGTGAAATAAAACTGCGAACCTGCTGCTATGAAGCTGAATATTGGGACTGTGCGAAGTGA
TTATGCTGGATTTAACAGCA

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MTNAALFLDRDGVINIDHGYVYQSQNFEFVPDIFDLVRTARNLDYKIIVITNQAGIGRGYYTEAQFHTLTQWMRQRFEDQ
NASIDAVYFCPFHPEHGVGYYRQESEFRKPNPGMFFQAAREHGLDLDRCVLVGDKISDIEAAAAAGIPVRFLFRSTDSCH
AAISISELVEVEQFLLKNLLEPDKQ

Sequences:

>Translated_185_residues
MTNAALFLDRDGVINIDHGYVYQSQNFEFVPDIFDLVRTARNLDYKIIVITNQAGIGRGYYTEAQFHTLTQWMRQRFEDQ
NASIDAVYFCPFHPEHGVGYYRQESEFRKPNPGMFFQAAREHGLDLDRCVLVGDKISDIEAAAAAGIPVRFLFRSTDSCH
AAISISELVEVEQFLLKNLLEPDKQ
>Mature_184_residues
TNAALFLDRDGVINIDHGYVYQSQNFEFVPDIFDLVRTARNLDYKIIVITNQAGIGRGYYTEAQFHTLTQWMRQRFEDQN
ASIDAVYFCPFHPEHGVGYYRQESEFRKPNPGMFFQAAREHGLDLDRCVLVGDKISDIEAAAAAGIPVRFLFRSTDSCHA
AISISELVEVEQFLLKNLLEPDKQ

Specific function: Converts the D-glycero-alpha-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-alpha-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=151, Percent_Identity=44.3708609271523, Blast_Score=159, Evalue=9e-41,
Organism=Escherichia coli, GI87082027, Length=150, Percent_Identity=28.6666666666667, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 21188; Mature: 21057

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNAALFLDRDGVINIDHGYVYQSQNFEFVPDIFDLVRTARNLDYKIIVITNQAGIGRGY
CCCCEEEEECCCEEECCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCC
YTEAQFHTLTQWMRQRFEDQNASIDAVYFCPFHPEHGVGYYRQESEFRKPNPGMFFQAAR
CCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEECCCCCCCCCCCHHHHHHH
EHGLDLDRCVLVGDKISDIEAAAAAGIPVRFLFRSTDSCHAAISISELVEVEQFLLKNLL
HHCCCHHHEEEECCCCCHHHHHHHCCCCEEEEEECCCCCHHEEEHHHHHHHHHHHHHHHC
EPDKQ
CCCCC
>Mature Secondary Structure 
TNAALFLDRDGVINIDHGYVYQSQNFEFVPDIFDLVRTARNLDYKIIVITNQAGIGRGY
CCCEEEEECCCEEECCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCC
YTEAQFHTLTQWMRQRFEDQNASIDAVYFCPFHPEHGVGYYRQESEFRKPNPGMFFQAAR
CCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEECCCCCCCCCCCHHHHHHH
EHGLDLDRCVLVGDKISDIEAAAAAGIPVRFLFRSTDSCHAAISISELVEVEQFLLKNLL
HHCCCHHHEEEECCCCCHHHHHHHCCCCEEEEEECCCCCHHEEEHHHHHHHHHHHHHHHC
EPDKQ
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11279237; 12101286 [H]