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The map label for this gene is gmhA [H]

Identifier: 114330189

GI number: 114330189

Start: 162252

End: 162836

Strand: Direct

Name: gmhA [H]

Synonym: Neut_0158

Alternate gene names: 114330189

Gene position: 162252-162836 (Clockwise)

Preceding gene: 114330188

Following gene: 114330190

Centisome position: 6.1

GC content: 50.6

Gene sequence:

>585_bases
ATGAGAAGCTACATTTATTCCCAGATTCAGGAAACCCAGCAGATCGTATCAGCTATGCTGGCGGATGAGGGGTTACTGTC
CCGTGTTGAAGCAGCAGCCCAAGCTTGTATCGGCTGTATGCAAGCAGGTAATAAAATCCTGCTGGCAGGTAATGGTGGCA
GTGCTGCTGATGCGCAGCATATCGCTGGAGAGTTTGTCAGCCGTTTTGCTTTTGATCGGCCGGGTCTGCCGGCAATTGCG
CTGACTACAGATACATCGATTTTGACTGCCATTGGTAACGACTATGGCTATGAAAATCTGTTTGCCCGGCAGGTGCAGGC
GCATGCGCAAAAAGGCGATGTATTCATTGCCTACTCTACTTCGGGCAAATCTTCCAACGTTTTGGCGGCATTGCAAATAG
CCAGGCAGAAAGAAGTTATTTGTATCGGCATGGCGGGTAACCGGGGTGGCCCGATGAAAAATTTATGTGACCATTATTTA
GACGTTCCGTCGGCGGATACGCCGAAGATTCAGGAAGGTCACGCCGTACTGGGCCATATCCTCTGTGGTTTGGTGGAGCG
TACGCTGTTCAAGGCTCCCATTTGA

Upstream 100 bases:

>100_bases
CAGAAAAACGGATGGATGTGATTCGCACTCTGAATAATTTCGGCGGGCAGGTAAGCAACTGCCATTTCACCAAAAATGGT
ACACAAGCCTGGAAGGTTAA

Downstream 100 bases:

>100_bases
TGGAAGCCATTATTCTGGCTGGGGGGCTGGGCACGCGCTTACGCAAGGTTGTGGCCGATGTACCCAAGCCCATGGCGCCT
ATTGCGGGTCGTCCATTTCT

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MRSYIYSQIQETQQIVSAMLADEGLLSRVEAAAQACIGCMQAGNKILLAGNGGSAADAQHIAGEFVSRFAFDRPGLPAIA
LTTDTSILTAIGNDYGYENLFARQVQAHAQKGDVFIAYSTSGKSSNVLAALQIARQKEVICIGMAGNRGGPMKNLCDHYL
DVPSADTPKIQEGHAVLGHILCGLVERTLFKAPI

Sequences:

>Translated_194_residues
MRSYIYSQIQETQQIVSAMLADEGLLSRVEAAAQACIGCMQAGNKILLAGNGGSAADAQHIAGEFVSRFAFDRPGLPAIA
LTTDTSILTAIGNDYGYENLFARQVQAHAQKGDVFIAYSTSGKSSNVLAALQIARQKEVICIGMAGNRGGPMKNLCDHYL
DVPSADTPKIQEGHAVLGHILCGLVERTLFKAPI
>Mature_194_residues
MRSYIYSQIQETQQIVSAMLADEGLLSRVEAAAQACIGCMQAGNKILLAGNGGSAADAQHIAGEFVSRFAFDRPGLPAIA
LTTDTSILTAIGNDYGYENLFARQVQAHAQKGDVFIAYSTSGKSSNVLAALQIARQKEVICIGMAGNRGGPMKNLCDHYL
DVPSADTPKIQEGHAVLGHILCGLVERTLFKAPI

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=182, Percent_Identity=39.010989010989, Blast_Score=134, Evalue=3e-33,
Organism=Escherichia coli, GI1786416, Length=188, Percent_Identity=37.2340425531915, Blast_Score=129, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 20583; Mature: 20583

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSYIYSQIQETQQIVSAMLADEGLLSRVEAAAQACIGCMQAGNKILLAGNGGSAADAQH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHH
IAGEFVSRFAFDRPGLPAIALTTDTSILTAIGNDYGYENLFARQVQAHAQKGDVFIAYST
HHHHHHHHHHCCCCCCCEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEC
SGKSSNVLAALQIARQKEVICIGMAGNRGGPMKNLCDHYLDVPSADTPKIQEGHAVLGHI
CCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LCGLVERTLFKAPI
HHHHHHHHHHCCCC
>Mature Secondary Structure
MRSYIYSQIQETQQIVSAMLADEGLLSRVEAAAQACIGCMQAGNKILLAGNGGSAADAQH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHH
IAGEFVSRFAFDRPGLPAIALTTDTSILTAIGNDYGYENLFARQVQAHAQKGDVFIAYST
HHHHHHHHHHCCCCCCCEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEC
SGKSSNVLAALQIARQKEVICIGMAGNRGGPMKNLCDHYLDVPSADTPKIQEGHAVLGHI
CCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LCGLVERTLFKAPI
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11373120; 12101286 [H]